Acebrophylline: Uses, Side Effects, Composition, Price & Dosages

A bronchodilator medicine, Acebrophylline is used to treat or prevent medical conditions such as blockage or irritation in the airways, asthma, chronic obstructive pulmonary disease, chest tightness and inflammation in lungs, other some airways/breathing related problems. Acebrophylline also has an anti-inflammatory property.


Uses and benefits of Acebrophylline:

Acebrophylline may be used for the treatment/prevention of various diseases and conditions such as:

  • Bronchitis
  • Chronic Obstructive Pulmonary Disease
  • Asthma
  • Relaxation of muscles
  • Lung aggravation cure
  • Cure of snugness in the chest
  • Common cold

Acebrophylline is also adviced for certain conditions other than mentioned here. The doctor may prescribe the medicine in combination with other drugs as well.

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Side Effects of Acebrophylline:

Patient may experience some minor and major side effects after the continued consumption of the drug. Some of the most common side effects associated with the capsule are:

  • Gastrointestinal Bleeding (Major)
  • Breathing Difficulties (Major)
  • Fever with cold (Major)
  • Increase in the speed of heartbeats (Major)
  • Mellow gastric aggravation
  • A headache
  • Sleeplessness
  • No sensation in the hand
  • Flatulence
  • Tipsiness
  • Abdominal problems
  • Diarrhea
  • Flatulence
  • Heartburn
  • Weakness
  • Frequent fluctuations in blood pressure

If one experiences any other major side effects, they must immediately seek medical attention.

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Dosage of Acebrophylline:

The drug dosage of Acebrophylline depends on various factors including:

  • Age of the patient
  • The weight of the patient
  • The severity of the disease
  • The response of the body to the first dose of the this drug
  • Medical history of allergies

Acebrophylline is available in the market in two major forms:

  • Tablet/Capsule
  • Syrup

Tablets are available in two strengths: (a) 100 mg and (b) 200 mg. For adults, the most common dosage advice by the doctors is 100 mg twice daily. To avoid gastrointestinal discomfort, It is always advised to be taken after food.

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Composition and Nature of Acebrophylline:

It is a xanthine derivative. It is advice as a bronchodilator for the treatment of conditions like inflammation in the lungs, bronchitis, chronic obstructive pulmonary disease, etc. Acebrophylline regulates the production of surfactant to reduce the bronchial obstruction. this drug works on some enzymes that are responsible for the constriction of smooth muscles. It is also helps make the mucus thinner, so that it moves faster and is easily eliminated from the airways.

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How to Use Acebrophylline?

  • It must be taken as directed by the doctor.
  • the sick person must also read the leaflet to check for the instructions on the use and storage of this medicine.
  • Depending upon the patient's condition and age, doctors may prescribe a syrup, tablet or capsule form Acebrophylline.
  • To avoid any digestive discomfort, it must be consumed only after food.
  • If a patient is taking the syrup form of this drug, they must do well to shake the medicine well before use. In addition, a measuring cup must be used to take the right amount of dosage of this medicine .

How Acebrophylline Works?

Acebrophylline is a bronchodilator that relaxes muscles associated and attached with the airways. Its nature makes the mucus thin and loosens its grip. It also prevents the release of inflammatory chemicals like leukotriene, etc. in the lungs reducing the inflammation in the lungs. Overall, It helps make the process of breathing easy.

When is Acebrophylline Prescribed?

Acebrophylline is prescribed for treatment of chronic obstructive pulmonary disease, Bronchitis and Asthma.

  • Bronchitis and Asthma – It is prescribed to alleviate the symptoms including irritation, blockage and swelling of the airways.
  • Chronic Obstructive Pulmonary Disease - It helps provide relief from symptoms such as shortening of breath, cough, wheezing and more.

Related Warnings/Precautions: When to avoid Acebrophylline?

There are certain warnings and precautions associated with the use of Acebrophylline. Some of these precautions and warnings are:

It must not be consumed by pregnant or breastfeeding women, without proper guidance or instruction of the doctor.

As It may interact severely with various diseases and conditions pertaining to heart and brain, gastrointestinal tract, and blood vessels, etc., it is advisable that patient share all the information related to their health conditions with their doctor before starting a course of the medicine.

It must not be consumed with caffeine, as it may cause severe reaction.

Do not smoke or consume tobacco while taking this medicine, as it may lessen the effect of the medicine.

Like pregnant and breastfeeding ladies, This drug is also not advisable to be used by the elderly, as it may lead to risk of severe and adverse effects.

One must not consume the tablet, if they are allergic to any of its content or if one has an Acute Myocardial infection.

It is not a replacement of an asthma inhaler. When there is a sudden asthma attack, It does not work immediately. So it is always better to keep the inhaler for emergencies.

patients having the following health conditions must not consume this medicine without prior discussion and consultation with the doctor

  • Arrhythmia
  • Hypersensitivity
  • Hemodynamic flimsiness
  • Liver Problems
  • Hypotension
  • Intense myocardial infection

Substitutes for Acebrophylline:

There are various substitutes of Acebrophylline available in the markets that have the same composition and strength:

  • Brophyle  manufactured by Zuventus Healthcare
  • Bigbro  manufactured by Intas Pharmaceuticals
  • AB Phylline manufactured by Sun Pharmaceuticals
  • Ascovent manufactured by Glenmark Pharmaceuticals
  • AB-Flo manufactured by Lupin Ltd
  • Macphylline manufactured by Macleods Pharmaceuticals
  • Acebrobid manufactured by Dr. Reddy’s Laboratories
  • Oxybro manufactured by Cadila
  • Xanilax manufactured by Torrent Pharmaceuticals
  • Oncet 3D manufactured by Medley Pharmaceuticals
  • Mucobus manufactured by Globus Remedies
  • Axeldox manufactured by Staunch Health Care Ltd.
  • Muciday manufactured by Seagull Labs

Acebrophylline Interactions:

Interaction with medicines -

The interaction of any drug depends on many factors and varies from person to person. It is advisable to check the interaction ability of the medicine before taking it.

Here is a little list of medicines with which this medicine may interact:

  • Azithromycin
  • Propranolol
  • Phenytoin
  • Cimetidine
  • Carbamazepine
  • Allopurinol
  • Erythromycin
  • Lincomycin
  • Clindamycin
  • Oxytetracycline
  • Propranolol
  • Phenytoin
  • Cimetidine
  • Cephalexin

Interactions with diseases –

Here’s a list of diseases with which this medicine may interact:

  • Hypotension or cardiogenic shock – It may severely interact with Hypotension or cardiogenic shock. Any incidence of a headache, tiredness or fainting after taking this drug must be reported to the doctor immediately.
  • Heart and blood vessel disorder – Regular monitoring of the condition may be required if a patient with heart and blood vessel disorder is planning to start the course of this medicine.
  • Liver/kidney impairment - It must be cautiously used by the patient with liver or kidney ailments. Doctors may prescribe dose adjustments to ensure that the medicine is working properly.
  • Seizure disorders - In sick person suffering from seizure disorders, an appropriate medicine to cure the condition may be given prior to prescribing this medicine.

Acebrophylline Variants:

Acebrophylline is available in different variants including tablets, syrups and capsules.

How to Store Acebrophylline?

One must follow the below mentioned storage information for Acebrophylline:

  • It must be kept it in a cool and dry place.
  • The medicine must not be exposed to direct heat or sunlight.
  • The drug should be kept away from the reach of pets and children.
  • It should be stored at a temperature between 15–30 degrees.

Frequently Asked Questions

1) What is Acebrophylline used to treat?

Ans: It is used for the treatment of respiratory system related disorders.

2) What diseases can be treated using this medicine?

Ans: Acebrophylline is used for the treatment of various medical conditions such as Bronchitis, Asthma and Chronic obstructive pulmonary disease.

3) What are the side effects of this drug?

Ans: Some of the most common side effects associated with the consumption of this medicine are gastrointestinal bleeding, fever with cold, headache, rapid heartbeats, mellow gastric aggravation, flatulence, diarrhea, sleeplessness, tipsiness, etc.

4) What could be the possible contradictions of consuming Acebrophylline?

Ans: It may prove to be fatal for sick person allergic to a medicine that belongs to the Xanthine derivative group. This medicine may also not prove to be a good option for patient suffering from acute myocardial infarctions.

5) How should a patient take Acebrophylline?

Ans: It must be taken in the dosages as directed by a certified doctor. In case a dose is missed, the patient must take it as soon as they remember it. However, if it is already time for the next dose, the missed dose must be skipped. One must never take more than the dose as it may lead to adverse reaction and drug toxicity.

6) Is Acebrophylline a habit-forming medicine?

Ans: No. Acebrophylline does not bear any habit-forming tendencies. All addictive drugs are classified under Schedule H or Schedule X in India. It makes sense to check the package for more details about the same.

7) Can smokers take this medicine?

Ans: Doctor may advise sick person to quit smoking while on Acebrophylline. Also, the patient may be asked to be careful about passive smoking as it may increase the chance of undesirable side effects. Apart from this, the patient may also be advised to avoid the consumption of marijuana and tobacco when using this medicine.

8) Is Acebrophylline safe for pregnant women?

Ans: Pregnant women are advised not to take Acebrophylline unless consulting by a doctor.

9) What happens if I take an expired Acebrophylline tablet?

Ans: Taking just a single dose of it may not produce any harmful effect. However, if a sick person has been unknowingly taking expired this medicine for a prolonged duration, it may lead to life-threatening reaction. Therefore, it is highly recommended that patient check the expiry date when purchasing the tablet.

10) When does this medicine start to show the effect?

Ans: The time taken for it to show its effect may vary from patient to patient.

11) Is Acebrophylline a steroid or an antibiotic?

Ans: It is neither a steroid nor an antibiotic. It is classified as a bronchodilator.

12) What are the major diseases treated by the medicine?

Ans: It is generally used to treat bronchial asthma and chronic obstructive pulmonary disorder.

13) Can Acebrophylline be taken with alcohol?

Ans: Taking Acebrophylline with alcohol may induce drowsiness and reduce the impact of the medicine. Therefore, it is advised that sick person must avoid taking the medicine with alcohol. Taking this medicine with excessive alcohol may even lead to life-threatening consequences.

14) Is it safe to drive or operate heavy machinery after taking Acebrophylline?

Ans: No, it is not recommended to drive or operate heavy machinery after taking Acebrophylline as this medicine may induce dizziness, headache, and low BP, etc.

15) Is the overdose of this medicine harmful?

Ans: Taking more than the dose of Acebrophylline may cause severe poisoning and side effects. If a patient has taken an overdose of medicine, it is advisable to consult a physician without any delay.

17) At what frequency does a person need to consume Acebrophylline?

Ans: Depending upon the patient's condition, doctors may prescribe a dose to be taken at different intervals. However, the most commonly advice frequency of taking an Acebrophylline formulation two to three times a day .

18) Should this medicine be taken empty stomach, before or after food?

Ans: To avoid any problem in the GI tract Acebrophylline must be taken after food .

19) Can I just stop taking Acebrophylline or I have to slowly wean off the use?

Ans: Certain medicines cannot be immediately stopped because they may exhibit some rebound effects. In case one thinks that it is not suiting, they must ask the doctor to prescribe a different medicine or change the dosage pattern.

20) Is this medicine safe for lactating mothers?

Ans: Acebrophylline may not be advisable to be taken by lactating mothers. In case there is an emergency, the doctor must be consulted before consuming the medicine.

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Last updated on : 10-05-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

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