Acemiz Plus Tablet: Uses, Side Effects, Composition, Price & Dosages

Acemiz Plus is a medicine that falls under the category of Non–Steroidal Anti-Inflammatory Drugs (NSAID). Acemiz Plus is prescribed to ease pain and reduce inflammation. The medicine provides relief in painful conditions associated with rheumatoid osteoarthritis, arthritis, and ankylosing spondylitis. Acemiz Plus is also commonly prescribed to provide relief from dental pain, headache, and fever. Acemiz Plus tablet is manufactured by Intas Pharmaceuticals Limited.

Nature of Acemiz Plus Tablet Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Composition of Acemiz Plus Tablet Aceclofenac (100mg) + Paracetamol/Acetaminophen (325mg)
Uses of Acemiz Plus Tablet Pain relief, fever, headache, muscle pain, toothache, sore throat, menstrual cramps, abdominal pain, and rheumatic conditions.
Side Effects of Acemiz Plus Tablet Allergy, drowsiness, swollen facial features, nausea and vomiting, shortness of breath.
Precautions of Acemiz Plus Tablet Patients with asthma, nose irritation, swelling on face, itchy red bumps on the skin, or stomach bleeding should not take this medicine.
Acemiz Plus Tablet

Uses and benefits of Acemiz Plus:

Acemiz Plus tablet is useful for treating various common health problems, some chronic diseases, and other acute disorders. A list of all the possible uses of Acemiz Plus tablet is given below:

  • Ankylosing Spondylitis
  • Rheumatoid Arthritis
  • Osteoporosis
  • Headache Back Ache
  • Joint pain
  • Stiff neck
  • Swelling
  • Pain at the site of injury
  • Pain in ear
  • Toothache
  • Flu
  • Period pain
  • Frozen shoulder
  • Gout

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Side Effects of Acemiz Plus:

Apart from the intended effects of Acemiz Plus, they are bound to show some side effects in some cases. These effects may or may not be life-threatening, but in case an individual experiences any side effect after consuming Acemiz Plus, they should seek immediate medical attention. Some of the side effects of Acemiz Plus are mentioned below:

  • Gas
  • Flatulence
  • Vomiting
  • Abnormalities of blood cells
  • Nausea
  • Feeling of sickness
  • Skin reddening
  • Shortness of breath
  • Swollen facial features
  • Liver damage
  • Rashes
  • Liver toxicity
  • Low white blood cell count
  • Acute renal tubular necrosis
  • Rash
  • Urticaria
  • Enuresis
  • Dizziness
  • Drowsiness

Read More: Myospaz Side Effects | Ovral Side Effects | Nicotex Side Effects

Common Dosage of Acemiz Plus:

The dosage of Acemiz Plus may vary from patient to patient.  Age of patient, severity of the ailment and other underlying health conditions are a few factors that help the doctor in deciding the dosage of Acemiz Plus Tablet. Commonly prescribed dosage of Acemiz Plus is twice daily with an interval of at least 4-6 hours.

  • Missed Dosage: One must take the missed dose as soon as possible. However, it is recommended not to take the missed dose if it is time for the next scheduled dose of Acemiz Plus. Under no circumstances should the patients take extra doses of the medicine to make up for the missed doses.
  • Over Dosage: An overdose of Acemiz Plus tablet may result in serious side effects. In the event of an overdose of Acemiz Plus, one must immediately consult a doctor. Diarrhea, nausea, sore lips and mouth, and skin rashes are a few symptoms of overdosage of this medicine.

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Composition and Nature of Acemiz Plus:

Acemiz Plus is a Non-Steroidal Anti-Inflammatory Drug (NSAID) that has following two active ingredients:

  • Aceclofenac (100 mg) : This ingredient is an NSAID which is useful in curing Ankylosing spondylitis, Osteoarthritis, Symptomatic treatment of pain and inflammation in Post-Traumatic pain, Cervical pain, Low back pain, Acute gout.
  • Paracetamol/Acetaminophen (325 mg) : Although Acetaminophen is an antipyretic, it also shows analgesic properties. Thus, it is used as a pain killer and also provides relief in fever too. This ingredient is useful in curing health conditions like migraine, acute gout, etc. It raises the pain threshold in the brain.

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Acemiz Plus Price in India:

Name Price
Acemiz Plus Tablet (Strip of 10 tablets) 82.45/- INR

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How Acemiz Plus Works?

Aceclofenac, an active ingredient of Acemiz Plus, acts as a cyclooxygenase inhibitor. A cyclooxygenase inhibitor stops the signals from centers of the brain that control body response of the pain caused by disease or injury thereby reducing pain and inflammation.

Acetaminophen works similarly by reducing pain signals from the site of pain to the brain, thereby reducing the pain. It also releases prostaglandins that match up with the body temperature to combat fever effectively.

How to Use Acemiz Plus?

Acemiz Plus tablet is prescribed to treat fever and painful conditions like menstrual pain, toothache, back pain, frozen shoulder, ear pain, gout, headache, along with other conditions like gout, rheumatoid arthritis osteoarthritis, and Ankylosing Spondylitis, etc.

One must always follow the directions of the doctor. Acemiz Plus must be swallowed whole and should not be chewed, broken or crushed. One must not increase or decrease the dosage without consulting the doctor. Absorption of Acemiz Plus is not influenced by food and thus it may be taken with or without food.

When is Acemiz Plus Prescribed?

Acemiz Plus is a Non–Steroidal Anti-Inflammatory Drug (NSAID) that is known to ease pain and reduce inflammation. Acemiz Plus is primarily used to provide relief in the painful conditions associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Doctors may also prescribe Acemiz Plus Tablet in case of fever, headache, dental pain, menstrual cramps and pain related to rheumatoid arthritis, etc.

Related Warnings/Precautions: when to avoid Acemiz Plus?

Acemiz Plus may cause dizziness in some cases and hence it is advised to avoid driving or operating heavy machines when taking Acemiz Plus. Other important points that should be taken into consideration before consuming this medicine include:

  • Hypersensitivity: Acemiz Plus is not recommended for patients with any kind of allergy to anti-inflammatory drugs. Avoid the usage of the drug if the patient has a hypersensitivity to Aceclofenac or Acetaminophen.
  • Kidney Disease: Acemiz Plus shows severe side effects in the patients with kidney issues. It should be used with extra care and caution by patients having a known history of kidney related disorder. Appropriate adjustment to the dosage and close monitoring of kidney function are required in such cases.
  • Liver Disease: Acemiz Plus shows adverse effects in the patients suffering from any kind of liver-related disorder. It should be used with extra care and caution in patients with known history of liver disease. Appropriate adjustment to the dose and close monitoring of liver function parameters are required in such cases.
  • Pregnancy: Use of Acemiz Plus in pregnant women should be avoided unless potential benefits outweigh the risks.
  • Breastfeeding: Acemiz Plus should be avoided by ladies during their lactation period as it may mix with blood and can harm the infant.
  • Bleeding Disorder: Acemiz Plus should not be used in case of any bleeding disorder as it may cause severe swelling and bleeding in abdomen, colon and anus.
  • Stomach Ulcers: Use of Acemiz Plus is not recommended if an individual is suffering from stomach ulcers . It may increase the chance of stomach bleeding.
  • Driving and operating heavy machinery should be avoided during the course of this medicine as signs of dizziness and drowsiness must be experienced. This hampers the mental alertness of the patient and hence performing activities like driving and operating heavy machinery is advised against.
  • Patients taking medicines for heart, kidney, asthma, and gastric problems should inform the doctor about the same to allow for required dose adjustment of Acemiz Plus tablet.
  • The medicine is not advised to be administered to children below 12 years of age.

Substitutes for Acemiz Plus:

In case of non-availability of Acemiz Plus, there are many alternatives in the market with exact same constituents and concentration. Given below is a list of a few of those alternatives:

  • Zerodol-P Tablet by Ipca Laboratories Ltd
  • Hifenac-P Tablet by Intas Pharmaceuticals Ltd
  • Dolokind Plus Tablet by Mankind Pharma Ltd
  • Acenac-P Tablet by Medley Pharmaceuticals
  • Dolowin Plus Tablet by Micro Labs Ltd
  • Topnac P Tablet by Systopic Laboratories Pvt Ltd
  • Aroff Plus Tablet by Unichem Laboratories Ltd
  • Willgo P Tablet by Panacea Biotec Ltd
  • Xrel 100 mg/325 mg Tablet by Deys Medical
  • Altraflam-P Tablet by Sun Pharmaceutical Industries Ltd
  • Aceclo Plus Tablet manufactured by Aristo Pharmaceuticals Pvt Ltd
  • Movon-P Tablet manufactured by Ipca Laboratories Ltd
  • Ibugesic AP Tablet manufactured by Cipla Ltd
  • Arflur-P Tablet manufactured by FDC Ltd
  • Zulu-P Tablet manufactured by Torrent Pharmaceuticals Ltd
  • Dolostat PC 100 mg/325 mg Tablet  manufactured by Blue Cross Laboratories Ltd
  • Altraflam-P Tablet  manufactured by Sun Pharmaceutical Industries Ltd
  • XREL Tablet  manufactured by Deys Medical
  • Willgo P Tablet  manufactured by Panacea Biotec Ltd
  • Aroff Plus Tablet  manufactured by Torrent Pharmaceuticals Ltd
  • Fenwin Plus 100mg/325mg Tablet  manufactured by Sun Pharmaceutical Industries Ltd
  • Anprox 100mg/325mg Tablet  manufactured by Seagull Pharmaceutical Pvt Ltd
  • Hhaceclo Plus Tablet  manufactured by Hegde and Hegde Pharmaceutical LLP
  • Feclojoy-P Tablet  manufactured by Inizia Healthcare Pvt Ltd
  • Kudzu Tablet manufactured by Vilberry Healthcare Pvt Ltd

Acemiz Plus Interactions with Other Drugs:

The drug Acemiz Plus may interact with certain products, drugs or medical conditions and cause adverse side effects. To avoid any complications, it is advised to discuss the ongoing medicines, medical history, and any supplements being administered with the doctor before starting the dose of this medicine.

Interaction with Medicines

Taking Acemiz Plus in combination with other over-the-counter medicines, herbal medicines or vitamin supplements may increase the risk of side effects. Acemiz Plus is known to negatively interact with the following drugs:

  • Corticosteroids
  • Digoxin
  • Lithium
  • Antihypertensives
  • Aspirin
  • Ibuprofen
  • Dalteparin
  • Aliskiren
  • Clopidogrel
  • Steroids
  • Diuretics
  • Drugs prescribed for lowering blood sugar levels in diabetic patients
  • Methotrexate
  • Hydantoins, barbiturates, carbamazepine, isoniazid, rifampin.
  • Cholestyramine and metoclopramide
  • Warfarin
  • Ciclosporin and Tacrolimus
  • Antibiotics like Quinoline
  • Zidovudine

Interaction with Diseases

Acemiz Plus tablet can interact with the following health conditions:

  • Kidney and Liver-related disorders: Patients with kidney or liver related disorders should avoid this medicine as it may worsen the condition and cause health complications.
  • Sensitivity to the medicine: Patients sensitive to Paracetamol, and Aceclofenac should not use this medicine.
  • Stomach related Disorders: Patients with on-going or history of repeated stomach ulcers or bleeding should completely avoid using this medicine.
  • Allergic Reactions: Patients with a history of allergic reactions as a response to aspirin, ibuprofen, or other NSAIDs should refrain from administering this medicine. The following symptoms may be experienced:
  • Asthma: This health condition gives rise to various breathing complications which can interact with the use of this drug. Hence the medicine should be avoided for such patients.
  • Heart-related problems: Patients suffering from serious heart failure and high blood pressure should completely avoid taking this medicine.
  • Acute rhinitis: A condition of inflammation of the mucosa of the nasal cavity (i.e. the lining of the nasal cavity). This medicine is advised against in patients suffering from this condition.
  • Utricaria: It is a skin rash triggered by a reaction to food, medicine or other irritants. Patients suffering from this condition should avoid using Acemiz Plus tablet as it may interfere with the medicine.
  • Hepatic Impairment: Acemiz Plus tablet should not be administered in case of a patient suffering from impaired liver functioning as it may worsen the condition.

Interaction with Alcohol

Acemiz Plus should never be combined with alcohol as Aceclofenac has a tendency to cause bleeding in the stomach due to interaction with alcohol.

Acemiz Plus Variants:

Acemiz Plus is available in two variants: tablet and suspension. Acemiz Plus containing Aceclofenac and Acetaminophen belong to NSAID; whereas, the suspension is an antihistamine that contains Astemizole as its main ingredient.

Medicines That Should Not be taken with Acezim Plus:

Mixing two or more medicines may change how the drug works and may increase the risk of side-effects. A few drugs that can react with Acemiz Plus are:

  • Lithium (Severe)
  • Antihypertensives (Severe)
  • Digoxin (Severe)
  • Corticosteroids (Moderate)

Acezim Plus Suspension form:

Acemiz Plus tablet is also available in the form of suspended syrup which is used in the treatment of allergic conditions:

  • Acemiz Plus 5mg Suspension

Is Acemiz Plus Banned In India?

No, the medicine is not banned in India and is readily available on all the medical stores.

How to Store Acemiz Plus?

  • It is advisable to store Acemiz Plus in a cool and dry place away from direct sunlight and moisture.
  • The medicine should be kept away from the reach of children and pets.
  • The packaging of Acemiz Plus Tablet must be kept intact in order to maintain its effect when being administered.

Purpose of Use:

The medicine is generally prescribed to alleviate pain and inflammation that occurs as a result of various medical conditions. Acemiz plus works by inhibiting the production of chemical compounds known as prostaglandins which are responsible for inducing an inflammatory response in the body.

Pro & Cons Tips When Taking Acemiz Plus:

  • The patients are advised to inform the doctor if they are allergic to Aceclofenac or paracetamol , or any other ingredients present in the medicine.
  • The patients must drink more water to reduce the chances of indigestion or stomach irritation.
  • The patients must inform the doctor if they are planning to become pregnant, because the medicine may make it difficult for a woman to conceive.
  • If the patient has a history of upset stomach, he/she must consume the medicine with milk or food only.
  • Prolonged use of the medicine must be avoided as it may increase the risk of stomach bleeding.

Acemiz Plus For Babies:

No, the medicine cannot be administered to children under the age of 18 years.

Acemiz Plus During Pregnancy:

Acemiz plus is not safe to be consumed by pregnant women. This is because the medicine may have severe side effects on the health of a developing fetus.


The medicine is composed of two active ingredients namely Aceclofenac and Paracetamol.

  • Aceclofenac - It is a non-steroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory properties. The medicine inhibits the activity of cyclo-oxygenase enzyme (COX) which is involved in the synthesis of inflammatory mediators called prostaglandins.
  • Paracetamol - The medicine has analgesic and antipyretic properties. The medicine is used to provide relief from fever and headaches associated with various conditions.


The medicine may exhibit side effects if a patient suffers from the following conditions –

  • Hypersensitivity to the ingredients present in acemiz plus.
  • Acute rhinitis
  • Allergy to Aceclofenac
  • Asthma
  • Active peptic ulcer
  • Hypersensitivity
  • Urticaria
  • Hepatic impairment

Frequently Asked Questions

1) What is Acemiz Plus tablet used to treat?

Ans: Acemiz plus is a combination of medicine which is composed of two salts namely Aceclofenac and Paracetamol. The medicine has anti-inflammatory (reduces redness and swelling), analgesic (pain reliever) and antipyretic (reduces fever) properties. It is usually prescribed to patients suffering from conditions such as:

  • Fever
  • Joint Pain
  • A Headache
  • Pain In The Ear
  • Rheumatoid Arthritis
  • Osteoarthritis
  • Ankylosing Spondylitis
  • Tooth Pain
  • Gynecological Pain

2) What are the side effects of Acemiz Plus tablet?

Ans: Acemiz Plus tablet has the following side effects:

  • Gas
  • Flatulence
  • Vomiting
  • Abnormalities of blood cells
  • Nausea
  • Feeling of sickness
  • Skin reddening
  • Shortness of breath
  • Swollen facial features
  • Liver damage
  • Rashes
  • Liver toxicity
  • Low white blood cell count
  • Acute renal tubular necrosis
  • Rash
  • Urticaria
  • Enuresis
  • Dizziness
  • Drowsiness

3) Is it safe to drive or operate heavy machinery after consuming Acemiz Plus tablet?

Ans – No, it is advisable not to drive a vehicle or operate heavy machinery if you experience dizziness, hypertension or any other side effects after consuming Acemiz Plus tablet. The medicine may hamper the mental ability of the patient and hence they are advised not to perform activities requiring high mental alertness.

4) Is it safe for pregnant and lactating women to administer Acemiz Plus tablet?

Ans: No, it is not safe for pregnant and lactating women to administer this medicine as it may cause serious side effects for the fetus or the nursing infant. It is best to consult the doctor regarding the patient’s health condition as the doctor would be able to suggest necessary dose adjustment or an alternative in case Acemiz Plus tablet is prescribed.

5) Can one stop taking Acemiz Plus tablet abruptly or should it be weaned off gradually?

Ans: it is advised not to abruptly discontinue the use of Acemiz Plus tablet and follow the complete prescription of the medicine as advised by the doctor. Stopping the medicine in the middle of the prescribed duration of treatment may result in recurrence of the health condition for which it was prescribed.

6) Is Acemiz Plus tablet habit forming?

Ans: No, Acemiz Plus tablet is not habit forming or addictive by nature. The medicines having addictive or habit-forming properties are listed under special schedules like schedule H or X. It is important to read the information in the packaging to ensure that Acemiz Plus Tablet does not fall under any of these categories. One is advised to not self-medicate or increase the dosage without the advice of the doctor.

7) Under what health conditions should Acemiz Plus tablet not be administered?

Ans: One is advised not to administer Acemiz Plus tablet to patients suffering from the following health conditions:

  • Kidney and Liver-related disorders
  • Sensitivity to the medicine
  • Stomach related disorders
  • Allergic reactions like:
  • Asthma
  • Heart-related problems
  • Acute rhinitis
  • Urticaria
  • Hepatic Impairment

8) Is Acemiz Plus tablet helpful in relieving stomach pain?

Ans: No, Acemiz Plus tablet is not advised to be taken for stomach pain unless prescribed by the doctor. The drug can increase stomach acid secretion which may aggravate an unknown underlying condition.

9) Is it safe to take Acemiz Plus tablet with vitamin B complex medicine?

Ans: Yes, administering Acemiz Plus tablet with vitamin B complex preparations is considered to be safe as no interactions have been reported. The Acemiz Plus tablet is used to relieve pain, vitamin B complex medicine can help fulfill the vitamin deficiency which may be responsible for the underlying painful condition.

10) Can the use of Acemiz Plus tablet cause damage to the kidneys?

Ans: Yes, long-term use of Acemiz Plus tablet can cause damage to the kidneys. Healthy kidneys are known to produce a chemical messenger called prostaglandins that protects them from damage. Using painkillers lowers the levels of prostaglandins in the body which leads to kidney damage following prolonged use of the medicine. Using painkillers is not recommended to patients with underlying kidney disease.

11) What are the risks associated with taking a higher dose of Acemiz Plus tablet?

Ans: Taking a higher dose of Acemiz Plus tablet can lead to increased probability of side effects like nausea, vomiting, heartburn, indigestion, diarrhea, and damage to the kidneys upon prolonged use. In case an increased severity of the pain is experienced or the pain is not relieved by the recommended doses of the medicine, it is important to seek medical assistance immediately.

12) What is the time taken for the onset of action of Acemiz Plus tablet?

Ans: Acemiz Plus tablet shows effects within 1.25 to 3 hours of oral administration.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

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