Acitrom 1 MG Tablet: Uses, Side Effects, Composition, Price & Dosages

Acitrom 1 mg is an anticoagulant or a blood thinner which is usually prescribed for the treatment and prevention of blood clots in the blood vessels. Acitrom 1 does not dissolve the blood clot that has been already formed but may prevent it from becoming larger. Acitrom is manufactured by Abbott India Limited.

Nature of Acitrom 1Mg Tablet: Anticoagulant
Composition of Acitrom 1 Mg Tablet: Acenocoumarol/Nicoumalone (1mg)
Uses of Acitrom 1 Mg Tablet: myocardial infarction, deep vein thrombosis, atrial fibrillation, pulmonary embolism
Side-effects of Acitrom 1Mg Tablet: Bleeding, Loss of appetite, Nausea and vomiting, Alopecia, Dizziness, headache
Precautions of Acitrom 1Mg Tablet: Pregnant women, hypersensitivity to acenocoumarol
Acitrom 1 MG Tablet

Uses and Benefits of Acitrom:

The drug is used for the prevention and treatment of blood clots in conditions such as -

  • Deep vein thrombosis
  • Heart Attack
  • Atrial fibrillation
  • Pulmonary embolism
  • Strokes

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Side Effects of Acitrom:

Some of the side effects associated with the consumption of Acitrom tablets are –

  • Blood in urine
  • Blurred vision
  • Alopecia
  • Headache
  • Loss of appetite
  • Nausea and vomiting
  • Dizziness

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Common Dosage of Acitrom:

The generally prescribed dose for Acitrom tablet is 1 tablet per day.  The doctor may increase or decrease the frequency of the medicine depending upon the condition of the patient.

  • Missed Dose : If a patient misses a dose of Acitrom tablets, it must be taken as soon as the patient remembers about it. However, if it is almost the time to consume the next dose, the previous dose must be skipped. It is advised not to consume two doses to compensate for the missed dose.
  • Overdose : Administering more than the prescribed dose of medicine may lead to severe side effects. If an overdose is suspected,  Must immediately visit a doctor.

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Composition & Nature of Acitrom:

It is an anticoagulant which is composed of Acenocoumarol. Acenocoumarol is a coumarin derivative which is used as an anticoagulant. Acenocoumarol inhibits the reduction of vitamin K by vitamin K reductase. This action prevents the carboxylation of vitamin K-dependent clotting factor VII, IX, X and II, thereby interfering with the coagulation process.

Acitrom Price in India:

Medicine Manufacturer Price
Acitrom 1 Tablet ( 1 strip of 30 tablets) Abbott Healthcare Pvt. Ltd. INR 199

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How to use Acitrom 1?

  • Acitrom 1 must be administered orally.
  • The tablets must not be chewed, broken or crushed prior to their consumption.
  • Acitrom 1 must be consumed at a fixed time.
  • Acitrom 1 can be consumed with or without food. However, patients must follow the direction of the doctor.

How Acitrom 1 MG Tablet works?

Acitrom comprises of Acenocoumarol which inhibits the activity of vitamin K reductase. This activity leads to the depletion of a reduced form of vitamin K (vitamin KH2) which is responsible for the carboxylation of glutamate residues. This inhibition of the carboxylation process leads to a decrease in the level of prothrombin and thrombin which reduces the thrombogenicity (the tendency of a material in contact with the blood to form a clot or thrombus) of clots.

When is Acitrom 1 Tablet prescribed?

Acitrom 1 is usually prescribed to prevent or reduce the formation of blood clots.  It may also be prescribed for the prevention and treatment of the following conditions –

  • Deep vein thrombosis
  • Heart Attack
  • Atrial fibrillation
  • Pulmonary embolism
  • Strokes

Warnings/Precautions- When to avoid Acitrom 1 MG Tablet?

Following are the precautions that must be adhered to while administering Acitrom tablets –

  • It is suggested to inform the doctor about any ongoing medications or treatment.
  • The patients allergic to the components of Acitrom are advised not to consume this medicine.
  • Patients allergic to Warfarin and other anticoagulants are advised not to consume this medicine.
  • Patients suffering from disorders that affect the absorption of food from the stomach are advised not to consume this medicine.
  • Patients suffering from conditions such as Tumors and Thyroid gland related disorders are advised not to consume this medicine as it may lead to severe drug and disease interaction.
  • Patients suffering from liver and kidney disease are advised to consume medicine with precaution.
  • It is suggested not to consume alcohol along with Acitrom as it may induce dizziness and drowsiness in patients.
  • The health of elderly people consuming this medicine must be carefully monitored as the medicine may lay a negative impact on the kidneys of the patients.

Substitutes for Acitrom:

Following are the substitutes of Acitrom tablets -

  • Acenomac 1 Tablet manufactured by Macleods Pharmaceuticals Pvt Ltd
  • Artiflo 1 Tablet manufactured by Zuventus Healthcare Ltd
  • Nicoz 1mg Tablet manufactured by Ajanta Pharma Ltd
  • Aceno 1mg Tablet manufactured by Zydus Cadila
  • Acethromb 1mg Tablet manufactured by Suvik Hitek Pvt Ltd
  • Nistrom 1mg Tablet manufactured by Neiss Labs Pvt Ltd
  • Altrom 1mg Tablet manufactured by Ikon Remedies Pvt Ltd

Acitrom Interactions:

Interaction with medicine

Following medicines may interact with Acitrom tablets and lead to severe side effects –

  • Heparin
  • Salicylic acid
  • Diflunisal
  • Clopidogrel
  • Ticlopidine
  • Phenylbutazone
  • Sulfinpyrazone
  • Sulfinpyrazone
  • Citalopram
  • Fluoxetine
  • Sertraline
  • Cimetidine
  • Clofibrate
  • Disulfiram
  • Ethacrynic acid
  • Glucagon
  • Paracetamol
  • Sulfonylurea derivatives
  • Thyroid hormones
  • Statins
  • Tamoxifen
  • Aminoglutethimide
  • Azathioprine
  • 6-mercaptopurine
  • Ritonavir
  • Nelfinavir
  • Phenobarbital
  • Carbamazepine
  • Cholestyramine
  • Griseofulvin
  • Rifampicin

It may also interact with the following class of drugs –

  • Non-steroidal anti-inflammatory drugs
  • Androgens
  • Anabolic steroids
  • Antiarrhythmic agents
  • Corticosteroids
  • Proton pump inhibitors
  • Plasminogen activators
  • Thrombin inhibitors
  • Prokinetic agents
  • Antacids
  • Antibiotics

Interaction with diseases

  • Kidney diseases – Kidney related ailments may experience some side effects with the consumption of this medicine. It is therefore advised, that patients suffering from kidney problems must administer the medicine only on the advice of the doctor.
  • Liver Diseases – Liver-related diseases may experience severe side effects due to the consumption of the tablets. Continuous monitoring of the liver condition may be required while administering Acitrom to the patients suffering from this diseases.

Interaction with alcohol

Acitrom 1 should not be consumed along with alcohol as it may induce excessive dizziness and drowsiness in patients.

Acitrom 1 MG Tablet Variants

Following are the variants of Acitrom tablets -

  • Acitrom 2 tablet
  • Acitrom 3 tablet
  • Acitrom 4 tablet
  • Acitrom 0.5 tablet

Medicines that should not be taken with Acitrom tablets

Following medicines should not be consumed with Acitrom tablets –

  • Fluoxetine
  • Sertraline
  • Cimetidine
  • Clofibrate
  • Disulfiram
  • Heparin
  • Salicylic acid
  • Diflunisal
  • Clopidogrel
  • Ticlopidine
  • Phenylbutazone
  • Sulfinpyrazone
  • Sulfinpyrazone
  • Citalopram
  • Ethacrynic acid
  • Glucagon
  • Carbamazepine
  • Cholestyramine
  • Griseofulvin
  • Sulfonylurea derivatives
  • Thyroid hormones
  • Statins
  • Tamoxifen
  • Aminoglutethimide
  • Rifampicin
  • Paracetamol
  • Azathioprine
  • 6-mercaptopurine
  • Ritonavir
  • Nelfinavir
  • Phenobarbital

How to store Acitrom?

  • Acitrom 1 must be stored in a cool and dry place.
  • The medicine must be kept away from the reach of children and pets.
  • Acitrom 1 must be kept away from direct heat or sunlight.

FAQs:

1) Is Acitrom safe to be consumed by pregnant women?

Ans: No. Acitrom 1 is not safe to be consumed by pregnant women. This is because the medicine poses a serious threat to the health ofa developing fetus. The medicine may be consumed by pregnant women only if the benefits outweigh the risks and Acitrom 1 is deemed absolutely necessary for consumption by the doctor.

2) Is it safe to drive after consuming Acitrom tablets?

Ans: Yes, it is safe to drive after the consumption of Acitrom tablet as Acitrom does not induce excessive dizziness or drowsiness in patients. However, if a patient experiences dizziness and drowsiness after the consumption of this medicine, driving must be avoided.

3)  What will happen if I accidentally consume an expired dose of Acitrom Tablet?

Ans: Although it is always recommended to check the expiry date of Acitrom before administering it, a single expired dose may not cause any severe side effects. It must be noted that the efficacy of the medicine may be affected as an expired tablet will not be as effective in treating the symptoms. In case of experiencing any severe side effects, a doctor must be consulted immediately to seek remedial action.

4)  Should I administer Acitrom Tablet before or after having a meal?

Ans: Acitrom can be consumed with or without food. It is recommended to follow the instructions given by the doctor on how to consume the medicine.

5) Does this medicine have a habit-forming tendency?

Ans: No. Acitrom does have any habit-forming tendencies.

6) Can Acitrom be used to prevent stroke?

Ans: Yes, Acitrom can be prescribed to prevent stroke. The medicine is an anticoagulant and prevents the blood from forming clots that obstructs the blood vessels, leading to a stroke.

7) What will happen if I continuously forget to take Acitrom?

Ans: Missing a single dose of Acitrom may not cause much effect. However, for a medicine to work properly some concentration of medicine should always be present in the body. If a patient continuously misses the dose of the Acitrom, the medicine may not be able to completely cure the condition it has been prescribed for.

8) What will happen if overdose on Acitrom tablet?

Ans: Acitrom works by inhibiting the activity of vitamin K which eventually reduces the time taken by blood to clot. However, consuming the medicine in more than prescribed doses may negatively affect the blood clotting time and lead to an increased risk of bleeding.

9)  What are the common side effects associated with Acitrom Tablet?

Ans: The common side effects associated with Acitrom Tablet are -

  • Blood in urine
  • Blurred vision
  • Liver injury
  • Alopecia
  • Headache
  • Loss of appetite
  • Nausea and vomiting
  • Dizziness

10)  Is Acitrom Tablet available as an Over- the- Counter medicine?

Ans: No, Acitrom is not an over-the-counter medicine. It can only be purchased after being prescribed by a doctor.

11) Can I take Acitrom Tablet along with other antidepressants?

Ans: No, antidepressants are not recommended to be administered along with Acitrom Tablets as they may interact and lead to severe side effects when co-administered. A doctor must be consulted for before starting the dose of any medicine to avoid the occurrence of drug interactions.

12) Can I immediately stop the consumption of this medicine as soon as I see improvement in my conditions?

Ans: No, it is not advisable to abruptly stop or alter the dosage of Acitrom even if an improvement in the condition is experienced. Leaving the course of medicine in between may not completely cure the condition it has been prescribed for. The doctor must be consulted before stopping the consumption of the medicine as he may prescribe an alternate dose if side effects persist.

13) What is Acitrom Tablet used for?

Ans: Acitrom Tablet is prescribed to reduce the formation of clots in the blood. Acitrom works by thinning the blood and reducing its ability to form clots. The medicine may be prescribed to provide relief in various conditions such as –

  • Deep vein thrombosis
  • Heart Attack
  • Atrial fibrillation
  • Pulmonary embolism
  • Strokes

14) Can Acitrom be prescribed to patients suffering from renal impairment?

Ans: No, Acitrom cannot be administered to patients suffering from severe renal impairment. This is because the medicine may lead to severe side effects in such patients. Close monitoring of the functioning of the kidney and regular dosage alteration may be required in such patients.

15) Is Acitrom safe to be consumed by lactating mothers?

Ans: Yes. It is safe to be consumed by lactating mothers. However, it is highly recommended that patients should administer medicine only if prescribed by a doctor.

16) What are the storage requirements for medicine?

Ans:

  • Acitrom  should be stored away from direct sunlight and heat.
  • It should be stored in a dry and cool place.
  • Acitrom should be kept out of reach of pets and children

17) Is Acitrom banned in India?

Ans: Acitrom is prescription only medicine which is readily available on all medical stores in India. The medicine can only be purchased after showing a prescription from the doctor.

18)  Is Acitrom a prescription-only drug?

Ans: Yes, Acitrom is a prescription-only drug. The medicine is generally used for the treatment and prevention of clot formation in the blood.  The medicine belongs to a category of anticoagulant drugs and cannot be purchased without a doctor’s prescription.

19) Do I need to avoid a particular food item while administering a dose of Acitrom Tablet?

Ans: Yes, the doctor may ask the patients to avoid the intake of cranberry juice or any product that contains cranberry extract. This is so because; cranberry may increase the risk of bleeding in patients administering Acitrom tablets.

20) What are the general precautions and warnings to be followed while taking Acitrom Tablet?

Ans:

  • It is recommended to inform the doctor about any ongoing medications or treatment.
  • The patients allergic to the components of Acitrom are recommended not to consume this medicine.
  • Patients allergic to Warfarin and other anticoagulants are recommended not to consume this medicine.
  • Patients suffering from disorders that affect the absorption of food from the stomach are advised not to consume this medicine.
  • Patients suffering from conditions such as Tumors and Thyroid gland related disorders are recommended not to consume this medicine as it may lead to severe drug and disease interaction.
  • Patients suffering from liver and kidney disease are advised to consume medicine with precaution.
  • Patients are advised not to consume alcohol along with Acitrom as it may induce dizziness and drowsiness in patients.
  • The health of elderly people consuming this medicine must be carefully monitored as the medicine may lay a negative impact on the kidney of the patients.

21) What if I miss a single dose of Acitrom?

Ans: It is generally advised to take the missed dose as soon as possible. If it is almost time for the next scheduled dose, it is recommended to administer the next dose and not take the skipped dose. Under no circumstance should a double dose be taken to compensate for the missed dose as it may lead to drug toxicity or other side effects.

22) How much time does it take for Acitrom to show its effect?

Ans: The effect of the medicine can be observed within 24 - 30 hours of administration of the dose.

23) What is the duration of effect of Acitrom tablets?

Ans: The effect of this medicine lasts for around 2 days.

24) Can I consume Acitrom along with alcohol?

Ans: No, it is not advisable to consume the medicine with alcohol as alchohol may reduce the effect of the medicine.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

User Comments (1)

A

Ayad

Sun Apr 21 2019

I have lost appetite and complain of nausea.the doctor has prescribed Acitrom to me because he did 2heart valve replacement .what drug can I take for nausea .

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