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Amoxyclav Tablet: Uses, Side Effects, Composition, Price & Dosages

Amoxyclav Tablet is a penicillin medicine that treats bacterial infections. It works by preventing the synthesis of the cell wall in bacterium stopping the bacterial growth.

Nature: Penicillin Antibiotic
Uses:

Urinary Tract Infection, Throat Infection,

Gonococcal Infection, Lower Respiratory Infection,

Ear Infection, Skin Infection, Stomach Ulcers,

Typhoid Fever, Swollen heart walls,

Infection of gums, Tonsillitis/ Pharyngitis

Composition: Amoxicillin (500 mg) and Clavulanic Acid (125 mg)
Side Effects:

Diarrhoea, Nausea, Vomiting, Fever, Joint pain,

Yellowing of skin, Heavy menstrual bleeding,

Unusual bruises and bleeding, Convulsions,

Altered sense of taste

Precautions:

Renal diseases, Mononucleosis, Colitis,

Pregnancy, Lactation, Allergy

Amoxyclav Tablet


It is used to treat numerous bacterial infections such as infections of the skin, urinary tract, lungs and airways. It can also be used in other conditions such as pneumonia, tonsillitis, bronchitis, sinus and STIs like gonorrhoea. It is manufactured by Abbott Health with two active ingredients namely - Amoxicillin and Clavulanic Acid.

Uses and Benefits of Amoxyclav Tablet:

It is used for the treatment of several bacterial infections, such as:

  • Skin and skin structure infections caused by bacteria
  • Urinary tract infections, bladder infections (Cystitis) and kidney infections (Pyelonephritis) caused by bacteria along with gonorrhoea and associated infections in the urinary tube and the region around the reproductive organs
  • Bacterial infections of the respiratory tract including the lower respiratory tract, such as acute bronchitis, and pneumonia
  • Otitis media or ear infections caused by Staphylococci and Streptococci
  • The treatment of nasal infections caused by bacteria
  • Treatment of infections in the throat and airways leading to lungs known as tonsillitis and pharyngitis
  • Treatment of typhoid and paratyphoid fever
  • Stomach ulcer treatment caused by Helicobacter pylori
  • An infection of gums that result in the formation of pus at the roots of the teeth
  • Preventive treatment of endocarditis, a condition where the inner walls of the heart swell

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Side Effects of Amoxyclav Tablet:

Apart from the intended effects of the medicines, patients may also experience some side effects in some cases. These side effects may or may not be life-threatening, but in case someone experiences any side effect after consuming this Tablet, they must seek immediate medical attention.

Just some of the many side effects of the medicine are:

  • Diarrhoea
  • Nausea and vomiting
  • Fever
  • Joint pain
  • Yellowing of skin
  • Heavy menstrual bleeding
  • Unusual bruises and bleeding
  • Convulsions
  • Confusion
  • Tooth discolouration
  • Hypersensitivity
  • Altered sense of taste

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Common Dosage of Amoxyclav Tablet:

The patient should administer Amoxyclav Tablets in accordance with the instructions prescribed by the doctor.  Doctors usually prescribe one tablet of Amoxyclav 625 in a day. However, the dosage may vary with the severity of the ailment to be treated. A few other factors that help in deciding the dosage are the BMI of the patient, age of the patient and other underlying health concerns.

  • Missed Dosage: The patient should take the missed dose as soon as it is remembered. However, it is advisable not to take the missed dose if it is almost time for the next dose.  Under no circumstance, a double dose should be taken to compensate for the missed dose as it may lead to drug toxicity or other side effects.
  • Over Dosage: Consuming the medicine more than the prescribed amount may show serious side effects such as abdominal pain, diarrhoea , vomiting, rashes, itching and dizziness . Thus, one should refrain from taking an overdose. However, if an overdose is suspected, one must rush to a doctor to seek immediate medical attention.

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Composition & Nature of Amoxyclav Tablet:

Amoxyclav Tablet is a penicillin antibiotic that contains two active ingredients - Amoxicillin and Clavulanic Acid.

Warnings/Precautions - When to avoid Amoxyclav Tablet?

A few concerns that should be taken into consideration before consuming this medicine include:

  • Hypersensitivity : Amoxyclav is not recommended for patients with any kind of allergy to antibiotics or penicillin. Avoid the usage of the drug if an individual has a hypersensitivity to Amoxicillin or Clavulanic Acid.
  • Kidney Disease : Amoxyclav shows severe side effects in patients with an impaired kidney. It should be used with extra care and caution in patients having a known history of kidney related disorder. Appropriate adjustment to the dosage and close monitoring of kidney function are required in such cases.
  • Liver Disease : Amoxyclav shows adverse effects in the patients suffering from any kind of liver-related disorder. It should be used with extra care and caution in patients having a known history of liver disease. Appropriate adjustment to the dose and close monitoring of liver function parameters are required in such cases.
  • Mononucleosis : Use of Amoxyclav is not advisable in patients suffering from mononucleosis. The medicine may result in bumps and rashes on skin in such condition.
  • Colitis : Amoxyclav Tablets should be administered cautiously to patients suffering from colitis or any other gastrointestinal disorders. Also, if the patient experiences abdominal discomfort, diarrhoea or bloody stools, a doctor should be consulted immediately.
  • Pregnancy : Use of this medicine in pregnant women should be avoided unless potential benefits outweigh the risks.
  • Breastfeeding : This medicine should be avoided by ladies during their lactation period as it may mix with blood thereby can harm the infant.

A few other precautions and warnings that should be considered before and during the duration of Amoxyclav are:

  • Amoxyclav is a penicillinantibiotic that shows various side-effects when used for a prolonged duration.  It is advised that the patient should not administer the tablets for more than 14 days.
  • Use of Amoxyclav without suspicion of a bacterial infection should be avoided. Irrational dosing may result in an increased risk of development of bacteria that are drug resistant. In addition, such usage may also result in toxicity.
  • The patients must inform the doctor about current medications and over the counter products they have been using in order to avoid severe interactions and side effects.
  • The doctor must also be informed about any pre-existing allergies and diseases to ensure that no side-effect occurs.
  • The medicine should not be consumed if it has passed the expiry date.

Substitutes for Amoxyclav:

Commonly found substitutes for Amoxyclav include:

  • Wocklav Tablet manufactured by Wockhardt Ltd
  • Bestomax Tablet manufactured by BestoChem Formulations India Ltd
  • Moxikind-CV manufactured  by Mankind Pharma Ltd
  • Clavidur Tablet manufactured by Lupin Ltd.
  • Augpen BID Tablet manufactured by Zuventus Healthcare Ltd

Amoxyclav Tablet Interactions with Other Drugs:

Drug interactions:

Taking Amoxyclav in combination with other over the counter medicines, herbal medicines or vitamin supplements may increase the risk of side effects. Amoxyclavis known to negatively interact with the following drugs:

  • Methotrexate
  • Doxycycline
  • Warfarin
  • Ethinyl Estradiol
  • Live Vaccines
  • Probenecid
  • Allupurinol
  • Exanatide
  • Chloroquine
  • Tramadol
  • Mycophenolate mofetil
  • Magnesium Citrate
  • Proton pump inhibitors such as rabeprazole, omeprazole
  • Antibiotics such as tetracycline, doxycycline

Lab Interactions:

Amoxyclav may interact with the following lab tests:

  • Urine Sugar Test: This medicine can affect the results of lab tests that measure the level of glucose in urine. As a result, a false-positive test may be reported.

Disease Interactions:

Acemiz Plus should never be consumed in case of:

  • Mononucleosis
  • Renal Dysfunction
  • Colitis
  • Renal Impairment
  • Impaired Liver Function

Amoxyclav Variants:

Here are the some of the most commonly available variants of the Tablet:

  • Amoxyclav 625 Tablet
  • Amoxyclav 375 Tablet
  • Amoxyclav 875/ 125 mg Tablet
  • Amoxyclav 200 mg/ 28.5 mg Syrup
  • Amoxyclav 1000 mg/ 200 mg Injection

Amoxyclav Tablet Price in India:

Variant Price (in Rupees) Quantity
Amoxyclav 625 Tablet 113.25 6 Tablets
Amoxyclav 375 Tablet 221.71 10 Tablets
Amoxyclav 875/ 125 mg Tablet 158.75 10 Tablets

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How Amoxyclav Tablet Works?

Amoxyclav with its active ingredients Amoxicillin and Clavulanic Acid works by inhibiting the production of the bacterial cell wall and thereby killing the bacteria. This killing of bacteria is achieved by transferring a peptide group in the transpeptidation process.

How to Use Amoxyclav Tablet?

Amoxyclav Tablets should be consumed as per the prescription of the doctor or the patient should follow the directions prescribed on the label. One must not increase or decrease the dosage without consulting the doctor. It is advised to swallow the tablet as a whole, without chewing, crushing or breaking it.

As food helps in a better absorption of Amoxyclav Tablets, the tablets should be consumed with food or immediately after food. For better results, it is advised that the patient should consume the tablets at evenly spaced intervals.

When is Amoxyclav Tablet Prescribed?

Amoxyclav is a penicillin antibiotic, used to treat a variety of bacterial infections. It is primarily used to treat infections in the the throat, respiratory tract, urinary tract and middle ear. Doctors may also prescribe this medicine in certain cases of pneumonia, gonorrhoea, typhoid fever, stomach ulcers , dental abscess, skin infections and endocarditis.

Medicines that should not be taken with Amoxyclav Tablet:

Mixing two or more medicines may change how the drug works and may increase the risk of side-effects. A few common drugs that can react with this medicine are:

  • Methotrexate (Moderate)
  • Doxycycline (Severe)
  • Warfarin (Severe)
  • Ethinyl Estradiol (Severe)

Amoxyclav Tablet Suspension form:

Amoxyclav is available in both tablets as well as suspension form. The suspension form is available as Amoxyclav Syrup with the following composition:

  • Amoxycillin (200mg/ml)
  • Clavulanic Acid (28.5mg/ml)

How to Store Amoxyclav Tablet?

It is advisable to store the medicine in a cool and dry place away from the reach of children and pets. The packaging of the medicine must be kept intact in order to maintain its effect when being administered.

FAQs

1) Is Amoxyclav addictive?

Ans: No, Amoxyclav is not at all addictive or habit forming.

2) Is Amoxyclav an antiviral?

Ans: No. Amoxyclav is a penicillin antibiotic and cannot be used to treat viral infections.

3) Can I take Amoxyclav while suffering from jaundice?

Ans: No, Amoxyclav shows harsh effects on liver and hence it is not advisable to consume this drug in jaundice or in any other liver-related disease.

4) Will I suffer from diarrhoea after taking Amoxyclav?

Ans: One of the most common side-effects of Amoxyclav is diarrhoea. Though it is a common occurrence, it is not essential that all patients suffer from it.

5) Is Amoxyclav safe to use?

Ans: Amoxyclav is a penicillin antibiotic that shows a number of side-effects. It is safe to use only till the time its benefits outweigh the side-effects. People with kidney related disorder and liver diseases and ladies during their pregnancy or lactation period should avoid this drug.

6) Is Amoxyclav a narcotic substance or a steroid?

Ans: Amoxyclav is neither a narcotic substance nor a steroid. It is a penicillin antibiotic that is used to treat a number of bacterial infections in the body.

7) Should I stop taking Amoxyclav if my symptoms of infection are relieved?

Ans: No, continue it for the specific time for which the doctor has prescribed the medicine or consult a doctor before discontinuing it.

8) Can I take Amoxyclav with alcohol?

Ans: Although, Amoxyclav shows no interaction with alcohol, yet it should not be taken with alcohol as it can cause an increased risk of the side-effects.

9) Can I get Amoxyclav without a prescription?

Ans: No. Amoxyclav is a penicillin antibiotic that is difficult to get without a prescription.

10) Is Amoxyclav safe to use in case of kidney related disorder?

Ans: No, severe interactions have been reported by the patients suffering from kidney disease and taking Amoxyclav. Talk to your doctor about your pre-existing medical conditions before consuming this medicine; he may adjust the dosage.

11) Is Amoxyclav safe to be consumed by pregnant women?

Ans: No . Amoxyclav Tablet is not safe to be consumed by pregnant women. This is because the medicine poses a serious threat to the health of the developing foetus. The medicine may be consumed by pregnant women only if the benefits outweigh the risks and the medicine is deemed absolutely necessary for consumption by the doctor.

12) Is Amoxyclav Tablet safe to be consumed by lactating mothers?

Ans: No, use of Amoxyclav is strictly prohibited in by lactating mothers. The medicine may adversely affect the health of the infant. If absolutely necessary, lactating mothers must hold from breastfeeding the infant until the medicine is completely eliminated from the body. For case-specific recommendations, consult a doctor.

13) What is Amoxyclav used for?

Ans: Amoxyclav is a combinational medicine that belongs to the class of drugs known as ‘Aminopenicillins’. It is primarily used to fight bacterial infections, especially those in the urinary tract and respiratory tract. Amoxyclav also helps cure ear infections, throat infections, skin infections, stomach ulcers, febrile neutropenia, nose infection and infection in the lower respiratory tract.

14) What are the possible side effects of Amoxyclav Tablet?

Ans: A few possible side effects of Amoxyclav Tablet are diarrhoea, nausea and vomiting, fever, joint pain, yellowing of the skin, heavy menstrual bleeding, unusual bruises and bleeding, convulsions and altered sense of taste.

15) What is Amoxyclav used to treat?

Ans: Amoxyclav is a combinational medicine that belongs to the class of drugs known as ‘Aminopenicillins’. It is primarily used to treat bacterial infections, especially those in the urinary tract and respiratory tract. It may also be used to treat ear infections, throat infections, skin infections, stomach ulcers, febrile neutropenia and nose infection.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

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