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Betnovate-N Cream : Uses, Side Effects & Composition

Betnovate N ointment is a topical corticosteroid and an anti-inflammatory ointment which is used for the fast and effective treatment of skin infections such as Eczema, Dermatitis, Psoriasis, etc. These skin infections are mainly bacteria-induced infections.


Nature of Betnovate N                Topical Corticosteroids and Anti-Inflammatory Ointment
Composition of Betnovate N       Betamethasone and Neomycin
Uses of Betnovate N    Skin disorders like eczema, dermatitis, allergy, eye, and joint inflammation
Side effects of Betnovate N          Skin itchiness, drying or cracking of skin, acne, changes in skin colour, persistent infections.
Precautions of Betnovate N           People suffering from bacterial or fungal skin infections and anal or genital itching.


 Betnovate N cream provides rapid relief from the irritation and soreness caused by these skin conditions. Betnovate N ointment is manufactured in India by Glaxo SmithKline Pharmaceuticals Ltd.

Uses and Benefits of Betnovate N:

Betnovate N is used to treat the following health conditions and symptoms:

  • Redness, swelling, itchiness of the skin
  • Eczema – A condition in which the patches of the skin become inflamed, itchy, red, cracked and rough.
  • Dermatitis – It is a common term used for various types of skin rashes. It can be classified into two types – atopic dermatitis and contact dermatitis. Atopic dermatitis is inherited and usually occurs in infants. Contact dermatitis occurs when the skin comes in contact with something that is causing an allergic reaction or injures the skin.
  • Psoriasis – A condition in which skin cells build up and form scales and itchy, dry patches.
  • Allergic conditions – The reaction of the immune system to a foreign substance.
  • Bacterial skin infections – An infection of the skin which can be caused by bacteria, fungus, viruses, and parasites.
  • Microbial infections – infections such as malaria, athlete’s foot, common cold are all caused by severe pathogenic bacteria.
  • Contusions – A contusion, which is a type of hematoma, develops when an injured capillary or blood vessel leaks blood into the surrounding area.
  • Itching – An irritating sensation that makes one want to scratch the skin repeatedly.
  • Inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses


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 Side Effects of Betnovate N: 

The following side effects may occur during the administration of Betnovate N:

  • Burning sensation
  • Itchiness
  • Redness
  • Irritation at the site of application of ointment
  • Allergy to the ointment or ingredients
  • Skin thinning
  • Dryness
  • Swelling or redness
  • Irritation
  • Secondary infections
  • Abnormal skin sensation
  • Hypertrichosis

Active ingredients of Betnovate N may affect cause other side effects in infants, pregnant women and elderly people with pre-existing kidney related ailments.


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Common Dosage of Betnovate N:

It is recommended to use Betnovate two or three times a day by rubbing gently on the skin. The progress of the administration and treatment should be monitored by the doctor on regular basis.

The Betnovate N is only used for curing skin conditions induced by bacterial infections. It is an anti-bacterial which provides rapid relief from the skin inflammations, swelling, and itching.

It is advisable to consult the doctor before the administration of Betnovate N to avoid the occurrence of unwanted side effects. 


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Composition & Nature of Betnovate N:

The major constituents of Betnovate N are as follows:

  • Betamethasone (0.1%) acts as a Valerate which is useful in reducing swelling, itching, and redness that may occur due to various types of conditions.
  • Neomycin Sulphate (3%) is an anti-bacterial component which helps in treating skin infections caused by bacteria.
  • Chlorocresol is a preservative component.
  • White soft paraffin, cetomacrogol 1000 acts as the base.

No colouring agents, lanolin and parabens are present in the and hence it is completely safe for skin infections.


Warnings and Precautions for Betnovate N Cream

Before starting the administration of Betnovate N cream, it is advised to inform the doctor about any on-going medicines or herbal or vitamin supplements. Additionally, the following concerns should be taken into consideration before consuming the medicine:

  • Alcohol Consumption – No interaction of alcohol has been established with the use of Betnovate N cream. It is advised to consult a doctor about instructions related to use of alcohol during the course of Betnovate N cream.
  • Pregnancy and Breastfeeding – Use of Betnovate N cream has been reported to be unsafe for pregnant females. In the case of breastfeeding mothers, Betnovate N cream is safe to be used as it does not pass through the breast milk in a substantial amount. It is advisable to consult the doctor before administering the ointment as it may lead to the occurrence of adverse side effects.
  • If the following symptoms are experienced during the course of Betnovate N cream, it must be brought to the notice of the doctor immediately:
  • It is advised to avoid contact of the Betnovate N cream with eyes. In case of contact, one should wash the eyes with water immediately. In case the irritation persists, one should contact the doctor immediately.
  • In case children are being treated with Betnovate N cream, they are advised to avoid wearing plastic pants or tight-fitting diapers.
  • It is suggested not to wash the treated area after immediately applying Betnovate N cream. One must avoid the use of other products on the treated area unless directed by the doctor.
  • Applying an excessive amount of Betnovate N cream may result in pilling. It is advised to use a thinner layer or lesser quantity of the cream to prevent serious side effects.
  • It is important to clean and dry the area of the skin to be treated. One should wash their hands before application of Betnovate N cream.
  • It is advised not to use Betnovate N cream in the following health conditions:
  • Anal or genital itching


Betnovate N Substitute and Variants:

There are other similar drugs in the market which can be used as a substitute for Betnovate N:

  • Hydrocortisone
  • Beta Val
  • Nizoral
  • Betamycin N Cream


Betnovate N Interactions with Other Drugs:

Interactions with Medicines

Betnovate N cream may interact with the few medicines or elements:

  • Amlodipine
  • Mifepristone
  • Warfarin
  • Ethinylestradoil
  • Insulin
  • Ciprofloxacin
  • BCG vaccine

Interactions with Diseases

Betnovate N cream can react severely with the following health conditions:

  • Tuberculosis – it is caused by a bacteria called Mycobacterium tuberculosis which attacks the lungs but can also damage other parts of the body. The disease spreads through the air when a person infected with the tuberculosis of the lungs or throat coughs, sneezes, or talks.
  • Electrolyte imbalance – important parameters of a person’s health, the electrolyte levels indicate levels of potassium, magnesium, sodium or calcium. Any fluctuations in these parameters result in muscle spasms, weakness, twitching or convulsions.
  • Gastrointestinal perforations – also known as a ruptured bowel, is a hole in the wall of part of the gastrointestinal tract. Symptoms of this condition include severe abdominal pain and tenderness.
  • Myocardial infarction – commonly known as heart attack, this occurs when the blood flow decreases or stops to a part of the heart, causing damage to the heart muscle. The most common symptom is chest pain, discomfort which travels into the shoulder, arm, back, neck or jaw.
  • Ocular herpes infection – the condition is caused by the type 1 herpes simplex virus.  Eye (ocular) herpes is a common, recurrent viral infection affecting the eyes. It can cause inflammation and scarring of the cornea known as a cold sore in the eye.
  • Scleroderma and threadworm infection - Scleroderma infection is a chronic connective tissue disease generally classified as one of the autoimmune rheumatic diseases. Threadworm infection is a type of infection caused by pinworms which are tiny parasitic worms that infect the large intestines of humans.

It is hence advisable to consult the doctor and discuss the health concerns in order to facilitate correct diagnosis.

Interaction with Alcohol

The ointment may or may not interact with alcohol and hence it is suggested to consult the doctor to gain more knowledge.


Betnovate N Prices in India:

Name of the medicine                              Price
Betnovate N Ointment 20gmINR 30.30


How Does Betnovate N Work?

Betnovate – N, the combination of two drugs – Topical Betamethasone and Neomycin, is meant for treating skin inflammatory conditions, particularly the skin conditions caused by bacterial infections.

Topical betamethasone is the steroidal medicine that helps to block prostaglandins (a chemical messenger) which is responsible for skin irritation, itchiness, and redness of the skin.

While topical neomycin is the kind of antibiotic medicine that helps killing bacteria, it averts the production of certain important proteins, essential for the bacteria to carry out their functions.

Betnovate N cream decreases inflammation by inhibiting the migration of leukocytes and reduces the permeability of capillaries. It also inhibits prostaglandins and other inflammatory mediators.


How to Use Betnovate N?

It is advised to follow the doctor’s prescription before starting to use the cream. The following steps are suggested to be followed before using the cream:

  • Wash and dry the hands
  • Take a small amount of the cream and gently rub it on the affected area as directed by the doctor.
  • After application, wash and dry hands thoroughly unless the cream is used for treating the hands.
  • It is advisable not to use Betnovate N cream immediately before having a bath, shower or going swimming as otherwise, the effectiveness of the cream may reduce.
  • It is advised not to apply Betnovate N cream to the face unless specifically advised by the doctor.
  • In case the doctor has advised to use the cream on the face, prevent the cream from entering the eyes. It is advised to wash the eyes thoroughly in case the cream enters the eyes.


When is Betnovate N Prescribed?

Betnovate N is an anti-inflammatory prescribed for treating various skin related conditions such as eczema, psoriasis, dermatitis and other allergic conditions. Additionally, it is prescribed by skin specialists or dermatologists as a drug for treating bacterial infections of the skin. Betnovate N is free from parabens and colouring agents and is safe for direct application on the skin.


Is this medicine banned in India?

No, Betnovate is not banned in India. However, it legally requires a prescription to be dispensed.


Medicine that should not be taken with Betnovate N:

Using Betnovate N Cream in combination with other over the counter medicines, herbal medicines or vitamin supplements may increase the risk of its side effects. A few drugs that should never be combined with Betnovate N are:


  1. Amlodipine
  2. Mifepristone
  3. Warfarin
  4. Ethinylestradiol
  5. Insulin
  6. Ciprofloxacin
  7. BCG Vaccine


Betnovate N Mechanism:

  • Betnovate N, the amalgamation of two drugs - Topical betamethasone and neomycin, is meant for treating skin inflammatory conditions, particularly the skin conditions caused by bacterial infections.
  • Topical betamethasone is the steroidal medicine that helps blocking prostaglandins (a chemical messenger) which is responsible for skin irritation, itchiness and redness of the skin.
  • While, topical neomycin is the kind of antibiotic medicine that helps killing bacteria by averting the production of certain important proteins, essential for the bacteria to carry out their functions.


How to Store Betnovate N?

It is advisable to store Betnovate N Cream in a cool and dry place, away from direct heat and sunlight. One must keep the medicine away from the reach of children and pets. The packaging of this medicine must be kept intact in order to maintain its effect when being administered.


Betnovate N Cream FAQs:


1) Can I stop using Betnovate N cream when the symptoms are relieved?

Ans: The symptoms of the health condition may improve just before the infection is completely cured. It is advised not to stop the use of Betnovate N cream and complete the full course of the treatment even if relief is observed.


2) How should I use Betnovate N cream?

Ans: It is suggested to use Betnovate N cream as advised by the doctor or as per the instructions on the label of the medicine. Apply a thin layer of the Betnovate N on the affected area to avoid harmful side effects. The dose of Betnovate N as decided by the doctor will depend on the severity of the condition for which it is prescribed. It is advised to wash hands after using Betnovate N cream unless the Betnovate Nis used to treat infection of the hands. It is important to avoid contact of the Betnovate Nwith eyes.


3) What will happen if I use a higher than the recommended dose of Betnovate N cream for a long duration?

Ans: The administration of Betnovate N cream should be taken in strict adherence to the doctor’s prescription. In case the Betnovate N is used for longer duration in higher doses, it may alter the blood circulation and cause adrenal suppression and Cushing's syndrome. This can cause weight gain, high blood pressure and rounding of the face. Application of Betnovate N cream can lead to a change in the colour of the skin at the site of the application. As the thinning and weakening of the skin begins to take place, the veins beneath the skin get highlighted. In case serious side effects are witnessed, it is advisable to contact the doctor.


4) What are the instructions for the storage and disposal of Betnovate N cream?

Ans: The following considerations must be kept in mind in order to ensure the efficacy of the Betnovate N is maintained.

  • It is advised to store the Betnovate N in its original packaging or the container it was originally stored in to maintain its efficacy.
  • The container should be tightly closed to avoid exposure to air.
  • It is advised to store the Betnovate N as mentioned on the packaging.
  • The Betnovate N should be stored in a cool, dry place preferably where the temperature remains below 30 degrees celsius.


5) What are the reported allergic reactions caused due to the application of Betnovate N cream?

Ans: The following allergic reactions may occur with the use of Betnovate N cream:

  • Rashes
  • Itching
  • Swelling around lips, face, and throat
  • Red, itchy bumps on the skin


6) What are some useful tips to use Betnovate N?

Ans: Following the given tips during the treatment of Betnovate N cream will ensure better results and faster recovery:

  • It is important to consult the doctor before altering the use of Betnovate N cream.
  • It is advised not to cover the affected area with a bandage o any other airtight dressing unless advised by the doctor.
  • It is strictly advised not to smoke during the course of treatment of Betnovate N cream.
  • In case the patient has Eczema around a leg ulcer, using a topical corticosteroid may increase the risk of an allergic reaction or an infection around the ulcer.
  • Betnovate N cream may cause hair, skin or fabric staining. It is advisable to cover the application of Betnovate Nwith loose dressing to protect clothing.


7) How long is the duration of the effect of Betnovate N?

Ans: The duration of the effect of Betnovate N cream will vary from person to person and depends upon the health condition of the patient as well as the prescribed dosage. 


8) Is Betnovate N habit forming?

Ans: No, there is no habit-forming tendency associated with the use of Betnovate N cream.


9) When should one avoid using Betnovate N?

Ans: Betnovate N should not be used in case the patient has a history of hypersensitivity to any ingredient present in the ointment.


10) What are some serious side effects of using Betnovate N under tight dressings?

Ans: In case large areas of the skin are being treated with Betnovate, especially for a long time and under tight dressings, some of the steroid present in Betnovate  may get over absorbed into the body. This may cause the following effects:

  • stomach ulcers
  • delayed wound healing
  • increased body fluid
  • muscle weakness
  • increased chance of infection
  • excessive growth of facial and body hair
  • acne
  • high blood pressure
  • eye problems e.g. cataracts, glaucoma, and blurred vision

In event of occurrence of any negative effects, it is advised to consult the doctor to seek remedial action.


11) Is Betnovate N good for fungal infection?

Ans: Betnovate N is a topical steroidal cream that can be used to treat fungal infections. It contains Clioquinol, as one of its active ingredient, which helps prevent or clear up the fungal infections of the skin. Consult a dermatologist for before using the medicine.


12) Is Betnovate N good for scars?

Ans: Yes, Betnovate N is good for scars. It is a topical steroidal cream that is used to treat white and black scars on the skin. However, it should not be used to treat scars formed due to acne or pimples. For case-specific recommendations, one must consult a dermatologist.


13) Does Betnovate lighten skin?            

Ans: Yes, Betnovate lightens the skin. However, using Betnovate for skin lightening is not a safe method. You must consult a doctor to seek an alternative.


14) Can I use Betnovate N on my face?

Ans: You should use Betnovate N on your face unless prescribed by a doctor. If applied on face, the efficacy of the cream is reduced. Also, while applying the ointment on the face, make sure that it doesn’t come into direct contact with the eyes.

15) Can Betnovate N be used for dark spots?

Ans: Yes, Betnovate N can be used to treat dark spots.


16) Does Betnovate N remove pimple marks?

Ans: Betnovate N should not be used for pimple marks. Scars are formed due to any skin trauma, which can include acne. Once they are formed, you cannot get rid of them completely. Consult a dermatologist for proper treatment of acne and scars.


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Last updated on : 25-03-2019

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