Calcirol 60000 IU Granules: Uses, Side Effects, Composition, Price & Dosages

Calcirol is a vitamin D supplement that is used to treat disorders arising from vitamin D deficiency. Vitamin D is a necessary nutrient required for calcium and phosphate metabolism in the body. Calcirol is a useful fat-soluble vitamin synthesised in the human body from Cholesterol with the help of sunlight. Calcirol comes in various forms such as granules, tablets, capsules, soft gels, syrup and injections. However, Calcirol granules and tablets are the most commonly used forms of the medicine. Calcirol can be either taken as a supplement or in the form of fish and dairy products like salmon, sardine, cod liver oil, milk, mushroom etc. that contain Calcirol 60000 IU Granules.

Deficiency of Calcirol causes rickets among children and adults suffer from brittle bones known as Osteomalacia. Calcirol is generally an essential element to improve overall health and treat diseases related to bones, also referred to as Osteoporosis. It also helps maintain proper blood pH levels in our body.

Certain commonly observed symptoms arising due to deficiency of Calcirol are as follows:

  • Frequent bone fractures
  • Fragile and brittle bones
  • Excessive fatigue and weakness
  • Difficulty in logical thinking
  • Pain in bones and joints
  • Osteoporosis, Rickets etc.
  • Bone Cancer
  • Insulin resistance that prevents body to utilise Insulin properly thereby increasing blood sugar levels
  • Weak immune system and high risk of infections etc.

People suffering from Liver diseases, Celiac and Crohn’s disease or those with darker skin colour are prone to deficiency of Calcirol. This prescription medicine is manufactured and marketed by Cadilla Pharmaceuticals Limited.

Calcirol 60000

Uses and Benefits of Calcirol:

  • Osteoporosis : Calcirol is administered to manage the symptoms of osteoporosis that arise due to the deficiency of calcium. It helps treat conditions such as fragile and brittle bones.
  • Rickets : Calcirol are prescribed to treat rickets that softens and weakens bones of children, usually due to lack of calcium.
  • Supplement : Calcirol 60000 IU Granules is also used as nutritional supplement to fulfill the deficiency of vitamin d which guides important body functions.
  • Familial Hypophosphatemia: A rare inherited disorder characterized by impaired transport of phosphate and altered vitamin-D metabolism in the kidneys. As a result, the hypophosphatemia can lead to a skeletal defect called osteomalacia, or a softening of bones. Familial Hypophosphatemia can also lead to rickets.
  • Fanconi Syndrome: A rare disorder of kidney tubule function that results in excess amount of glucose, bicarbonate, phosphates (phosphorous salts), uric acid, potassium, and certain amino acids excreted in the urine.
  • Hypoparathyroidism : The calcirol prescription is given to treat symptoms of calcium deficiency which may arise due to deficiency of the Parathyroid hormone in the body.
  • Peripheral Neuropathy: Calcirol is used to treat symptoms relating to nerve damage.
  • Vitamin D3 deficiency: Calcirol is also used to treat vitamin D3 deficiencies in patients suffering from liver disease, Crohn’s disease, and celiac disease.

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Side Effects of Calcirol 60000 IU Granules:

In addition to the intended effects of Calcirol, certain side effects are commonly observed.

  • A headache and drowsiness.
  • Irritable mood.
  • Allergic reactions in sensitive individuals.
  • General weakness, muscle ache, and joint ache.
  • Dry mouth, metallic taste, constipation and loss of appetite.
  • Conjunctivitis and sensitivity to bright light.
  • Irregular heartbeat and high blood pressure.
  • Increased thirst, nausea, and vomiting.
  • Loss of body weight.
  • Other more serious symptoms include albuminuria and Azotemia and frequent urination.
  • Diarrhea
  • Decreased appetite
  • Dizziness
  • Skin rash
  • Chest pain and discomfort
  • Unusual tiredness
  • Increased urination
  • Itching
  • Metallic taste in the mouth

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Common Dosage of Calcirol:

Calcirol 60000 IU Granules must be consumed exactly as prescribed by the doctor. Care must be taken to take the medicine at regular intervals as prescribed, without any delays.

Missed Dose -

In case a dose Calcirol is missed, one should take it as soon as possible. In case it is already time for the next dose as per prescription, then the missed dose should be skipped and the next dose should be taken as scheduled. One should not take extra doses in order to make up for the missed dose.

Overdose -

In case Calcirol 60000 IU Granules is taken in a higher dose than prescribed, immediate medical attention must be sought.

An overdose may lead to the following:

  • Increased calcium levels in blood
  • Passing of calcium in urine
  • Increased phosphates in blood
  • Nausea
  • Vomiting
  • Anorexia
  • Weakness
  • Constipation
  • Headache
  • Bone pain
  • Later symptoms include increased frequency of urination (polyuria)
  • Increased thirst (polydipsia)
  • Aversion to bright light (photophobia)
  • Runny nose

Expired Dose -

  • An expired drug may not be as potent in treatment.
  • It is very unlikely for a single dose of expired Calcirol to produce an adverse event.
  • One must consult a physician if they feel unwell or sick after consuming an expired dose of Calcirol.

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Composition and Nature of Calcirol:

The calcirol are composed of vitamin D3 (60000 IU). Also known as Cholecalciferol, this vitamin D supplement is a secosteroid, which is a steroid molecule with one open ring.

Naturally, vitamin D3 is synthesized in the body by the action of sunlight on cholesterol (7-dehydrocholesterol).

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How Calcirol 60000 IU Granules Works?

Calcirol 60000 IU Granules come from the class of drugs called vitamins. This drug acts by increasing the intestinal absorption of calcium and phosphorus. Hence, it helps maintain calcium and phosphorus levels in the body. Calcirol aims at activation of vitamin D3 in the body. This helps improve the absorption of calcium, phosphate, and magnesium in the body.

Calcirol is a pro-vitamin that gets converted in the body to calcitriol and stimulates the absorption of calcium and phosphates from the intestine, kidneys and also regulates the release of calcium from bones to blood. This is how Calcirol work to manage Hypocalcemia, Hypophosphatemia, and Secondary Hyperparathyroidism.

Precautions and Warnings - When to Avoid Calcirol:

Before starting Calcirol 60000 IU Granules treatment, it makes sense to inform the doctor about other ongoing treatments, underlying ailments, and additional supplement consumptions.

  • Dosage of the medicine must not be exceeded from what is prescribed.
  • People allergic to Calcirol or any of its ingredient drugs must avoid Calcirol.
  • People with kidney or liver diseases must consult a doctor before starting a course of Calcirol 60000 IU Granules.
  • Use of Calcirol must not be stopped abruptly unless instructed by the doctor. Stopping the medication suddenly may lead to rebound effect.
  • Though there is lack of medical studies on the use of Calcirol for pregnant females, use of Calcirol is usually not recommended to pregnant women unless absolutely necessary. It is advised to begin supplementation a few months prior to pregnancy after consulting the doctor and evaluating the benefits and risks.
  • Use of Calcirol is not recommended unless absolutely necessary to lactating mothers. Since there is a lack of evidence from research, it is best to consult a doctor and evaluate the risks involved before consuming Calcirol.
  • Calcirol must be avoided in the following health conditions:

One must not take Calcirol 60000 IU Granules if:

  • The foil or packaging is torn or shows signs of tampering or there is discolouration.
  • It has passed the expiry date of the medicine printed on the pack.

Substitutes for Calcirol:

There are other medications available which may be used in place of Calcirol. These alternate medicines/substitutes include:

  • Calshine 60000 IU Sachet manufactured by Eris Life Sciences.
  • D3 Shot 60000 IU Sachet manufactured by Abbott Healthcare Private Limited.
  • Inta-D 60000 IU Sachet manufactured by Intas Pharmaceuticals Limited.
  • Dsol 60000 IU tablet manufactured by Cipla Limited.
  • Super D3 60000 IU tablet manufactured by Intas Pharmaceuticals Limited.
  • Lupi D3 Granules 1.30gm manufactured by Lupin Ltd.
  • Vitoc D 60000IU Granule 1gm manufactured by Cachet Pharmaceuticals Pvt Ltd.
  • Cipcal D3 60000IU Granules 1gm manufactured by Cadila Pharmaceuticals Ltd.
  • Vitanova D3 Granules 1gm manufactured by Zuventus Healthcare Ltd.
  • Minmin D3 60000IU Sachet 4's manufactured by RPG Life Sciences Ltd.
  • Macbrite D3 60000 IU Granules manufactured by Macleods Pharmaceuticals Pvt. Ltd.
  • Caldikind 60000 IU Granules manufactured by Mankind Pharmaceuticals Ltd.
  • Torflash Md 60000 IU Granules manufactured by Torrent Pharmaceuticals Ltd.
  • Brigeta 60000 IU Granules manufactured by Novartis India Ltd.
  • Celol D3 60000 IU Granules manufactured by Emcure Pharmaceuticals Ltd.
  • D Well 60000 IU Granules manufactured by Ranbaxy Laboratories Ltd.

Calcirol 60000 IU Granules Interactions with Other Drugs:

Calcirol 60000 IU Granules is known to interact with the following drugs and compounds –

  • Calcirol absorption can be reduced due to the intake of Cholestyramine, Cholestipol or Mineral oil.
  • Thiazide diuretics can increase the level of calcium in the blood.
  • Antacids and laxatives containing magnesium can prolong action time and cause hyper magnesia when taken with Calcirol.
  • Concurrent vitamin D and calcium supplement intake can cause hypercalcemia.
  • Corticosteroids reduce Calcirol efficacy.
  • Other drugs which cause a considerable reaction with Calcirol are Chloramphenicol, Omeprazole, Ranitidine, Phenytoin, and Metformin.
  • One must inform the doctor about any herbal supplements that they are taking and must not modify the drug regimen without doctor’s approval.

The following drugs have been identified to interact with Calcirol:

  • Acetaminophen
  • Aluminium hydroxide
  • Aspirin
  • Atenolol
  • Calciferol
  • Calcitriol
  • Ergotamine
  • Hydralazine
  • Hydrochlorothiazide
  • Methyldopa
  • Paricalcitol

Interaction with Alcohol: Interaction of Calcirol with alcohol is unknown. But it is advisable to consult the doctor before consumption.


1) Is Calcirol 60000 IU Granules addictive in nature?

Ans: No habit forming or addictive properties have been found in Calcirol 60000 IU Granules post medical studies conducted for research purposes.

2) What should I do in case I miss a dose of Calcirol 60000 IU Granules?

Ans: Take the missed dose of Calcirol as soon as possible. However, if it is already time for the next dose, skip the missed dose. Do not take a double dose in order to make up for the missed dose as it may result in serious health complications.

3) Is Calcirol safe for pregnant and lactating women?

Ans: Use of Calcirol is not recommended for pregnant women unless absolutely necessary. Due to lack of conclusive medical evidence, lactating mothers are advised to consult the doctor before taking the medicine.

4) What is the effect of Calcirol on body organs?

Ans: Calcirol dose adjustment becomes necessary in patients with kidney and liver diseases.

5) What are the storage considerations for Calcirol 60000 IU Granules?

Ans: Listed below are the storage conditions for Calcirol 60000 IU Granules:

  • Calcirol must be stored at room temperature away from direct sunlight and heat.
  • Keep Calcirol away from children and pets.
  • The ideal temperature for storing Calcirol is below 25 degrees Celsius.
  • A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
  • Do not use Calcirol after the expiry date given on the label.
  • The expiry date refers to the last day of that month.
  • Medicines should not be disposed of via wastewater or household waste.
  • Ask your pharmacist on how to dispose of medicines no longer required. These measures will help protect the environment.

6) What forms of Calcirol is commonly available? How can one take Calcirol?

Ans: Calcirol 60000 IU Granules usually comes in four forms:

  • Sachet containing granules
  • Tablets
  • Capsules
  • Injectable forms

Calcirol capsules and tablets are usually taken by mouth with a glass of water. Calcirol sachets containing Cholecalciferol granules can be mixed with milk. Ensure you use a measuring cup to take the correct dosage of medicine. To consume Calcirol Syrup, shake the suspension liquid well before each use to mix the medication evenly. Calcirol capsules are usually taken after food for better absorption. Injectable forms of Calcirol should be injected by trained healthcare professionals only.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

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