Calpol Tablet : Uses, Side Effects, Dosages & Price

Manufactured and marketed by Glaxo SmithKline Pharmaceuticals Ltd, Calpol is an analgesic and antipyretic drug that contains paracetamol as its active ingredient. It is primarily used to provide temporary relief in fever and mild pain such as toothache, backache, arthritis, headache and muscle pain. This medicine may also be used to relieve menstrual cramps.

Calpol is available in the market in both tablet as well as suspension form.

Nature: Analgesic + Antipyretic

Fever, Headache, Muscle Pain,

Osteoarthritis, Low Back Pain, Toothache,

Menstrual Pain, Cold/Flu Pain

Composition: Paracetamol
Side Effects:

Nausea, Vomiting, Pain in the abdomen,

Jaundice, Constipation, Diarrhoea,

Indigestion, High Blood Pressure,

Flatulence, Loss of appetite, Liver Toxicity


Hypersensitivity, Gastrointestinal Lesions,

Liver Diseases, Renal Impairment,

Pregnancy, Lactation, Elderly Population, Alcoholism

Calpol Composition and Nature:

Calpol tablet is a drug that shows analgesic and antipyretic properties. It contains Paracetamol (500mg) as its active ingredient. Depending upon the variant the strength and composition may vary.

Calpol Tablet Uses:

Calpol is an analgesic and antipyretic medicine that may be used to provide relief in the following conditions and diseases:

1. Fever : This medicine helps reduce fever. However, it does not treat the cause.
2. Headache : This medicine can provide relief from headaches and migraines.
3. Muscle pain : This medicine can provide relief from mild to moderate muscle pain.
4. Menstrual cramps : This medicine may also be used to provide relief in menstrual cramps
5. Post-immunization pyrexia : This medicine can provide relief from fever and pain caused after the administration of an injection.
6. Arthritis : This medicine helps alleviate the pain associated with arthritis.

Read More: Cefixime Uses | Caripill Uses

Calpol Tablet Side Effects:

Calpol Tablets are safe to use that does not show side effects. However, in certain cases, it may cause a few side effects. These include:

1.    Abnormalities of blood cells
2.    Allergic reactions
3.    Feeling of sickness
4.    Liver damage
5.    Nausea
6.    Rashes
7.    Shortness of breath
8.    Skin reddening
9.    Swollen in the face

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Calpol Tablet Dosage:

The patient should administer Calpol Tablets in accordance with the instructions prescribed by the doctor.  Doctors usually prescribe 2 to 3 tablets in a day. However, the dosage may vary with the severity of the ailment to be treated. A few other factors that help decide the dosage are the BMI of the patient, age of the patient and other underlying health concerns.

Missed Dosage :
The patient should take the missed dose as soon as it is remembered. However, it is advisable not to take the missed dose if it is almost time for the next dose.  Under no circumstance, the dosage should be doubled to compensate for the missed dose as it may lead to drug toxicity or other side effects.

Overdose :
Consuming the medicine more than the prescribed amount may show serious side effects or drug toxicity and thus one should refrain from taking an overdose. However, if an overdose is suspected, one must rush to a doctor to seek immediate medical attention.

How Calpol Tablet Works?

Calpol contains paracetamol as its active ingredient that works by inhibiting the COX (Cyclooxygenase) enzymes. This, in turn, blocks the secretion of Prostaglandins (pain causing chemicals) to relieve pain.
Prostaglandins are pain-causing chemicals that cause pain and inflammation and pain. To reduce fever, it helps increase the blood flow in the skin to cause sweating and heat loss.

Warnings/Precautions- When to avoid Calpol Tablet?

Following are the precautions that should be kept in mind before and during the consumption of Calpol Tablets:

1.    Use of Calpol should be avoided by the patients who are hypersensitive or allergic to Paracetamol or any other constituent of this medicine.
2.    Patients with a known history of renal or liver impairment must use Calpol only after due consultation with their doctor.
3.    The medicine should be avoided by patients suffering from chronic malnutrition.
4.    The doctor should be informed :

  • If the patient is pregnant or planning to conceive
  • If the patient is breastfeeding

5.    An overdose of Calpol medicine can cause adverse effects and drug toxicity.  If such symptoms appear, it is advised to consult a doctor immediately.
6.    The patients must inform the doctor about current medications and over the counter products they have been using in order to avoid severe interactions and side effects.
7.    The doctor must also be informed about any pre-existing allergies and diseases to ensure that no side-effect occurs.
8.    The medicine should not be consumed if it has passed the expiry date.
9.    In case the patient experiences any kind of side effect during the consumption of Calpol, the doctor should be consulted immediately.

Calpol Tablet  Substitutes:

Following is the list of a few medicines that have the same composition and strength as that of Calpol Tablet and hence can be used as its substitutes:

  • Glenpar 500 MG Tablet – manufactured by Glenmark Pharmaceuticals Ltd.
  • Lupipara 500 MG Tablet – manufactured by Lupin Ltd.
  • Paracad 500 MG Tablet – manufactured by Zydus Cadila
  • Parafast 500 MG Tablet – manufactured by Cipla Ltd.
  • Paro 500 MG Tablet – manufactured by Glenmark Pharmaceuticals Ltd.

Read More: L evolin Substitutes | Limcee Substitutes

Calpol Tablet Interactions:

A drug can interact with another drug, disease, food items and beverages that can lead to effects that are different from the intended ones. Calpol tablet interacts with the following drugs, diseases and lab test:

Interactions with drugs:

Mixing two or more medicines may change how the drug works and may increase the risk of side-effects. A few drugs that may interact negatively with Calpol are:

  • Carbamazepine: Calpol reacts with Carbamazepine and thus, must not be taken together. Interaction can cause chills, joint pain, and fever, loss of appetite and skin rash.
  • Phenytoin: Calpol reacts with Phenytoin and hence, should not be taken together as it can cause chills, joint pain, and fever, loss of appetite and skin rash.
  • Sodium Nitrite: Calpol reacts with Sodium nitrite and must not be taken together. It can cause dizziness, skin discoloration, headache, rashes and increased heartbeat.
  • Leflunomide: Calpol reacts with Leflunomide and must not be taken together as the interaction can cause skin yellowing, chills, fever and nausea.
  • Prilocaine: Calpol reacts with Prilocaine and must not be taken together. It can cause skin discoloration, dizziness, rashes, dizziness, increased heartbeat and headache.

Interactions with alcohol:

Interaction of Calpol Tablet with alcohol may result in some adverse effects on the health of the liver. It may also increase the risk of its side effects. Hence, it is advisable to discontinue the consumption of alcohol during the course of treatment.

Disease Interactions:

Calpol Tablets should be avoided by the patients suffering from:

  • Liver disease: It is not recommended for individuals suffering from liver diseases as it may cause severe effects. For this reason, if this medicine is taken then the liver function must be monitored closely. Some of the symptoms of drug interaction include dark urine, fever, rashes and nausea.

Lab Interactions:

  • 5-HIAA Urine Test: Calpol may interfere with the 5-HIAA Urine Test and gives a false-positive result. For this reason, if the patient is consuming this medicine, the doctor should be informed before taking this test.


Following are the variants of Calpol Tablet:

Calpol 500 Tablet
Calpol 650 Tablet
Calpol Plus Tablet
Calpol T Tablet


Calpol is available in both tablets as well as suspension form. The suspension form is available in the following four forms:

Calpol 250 Suspension
Calpol 120 Suspension
Calpol Paediatric Drops
Calpol 400 mg/ 325 mg Suspension

Usually, the suspension form is prescribed to children or patients who are not able to consume tablets.

Medicines That Should Not be Taken with Calpol:

Taking Calpol Tablet in combination with other over the counter medicines, herbal medicines or vitamin supplements may increase the risk of its side effects. A few drugs that should never be taken with Calpol Tablets are:

1.    Benzydamine (moderate)
2.    Warfarin (moderate)
3.    Antifungals (moderate)
4.    Metamizole (moderate)

Price Table:

Variant Price (in INR) Quantity
Calpol 500 Tablet 14.09 15 Tablets
Calpol 650 Tablet 31.50 15 Tablets
Calpol Plus Tablet 38.26 10 Tablets
Calpol T Tablet 69. 90 15 Tablets

How to Store:

Calpol Tablets should be stored in a cool and dry place away from direct heat and sunlight. The packaging of this medicine must be kept intact in order to maintain its effect when being administered. One must keep the medicine away from the reach of children and pets.


1) How long does the effect of Calpol tablet last?

Ans: The effect of Calpol tablet lasts on an average for 4 to 6 hours.

2) How much time does it take for Calpol tablet take action?

Ans: It takes an hour or so for the Calpol tablet shows its effect. However, if this medicine does not provide relief even after a day, the patient must consult a doctor.

3) Is Calpol tablet safe for use during pregnancy?

Ans: Effect of Calpol Tablets on foetus is not known and thus it is better to consult a doctor before taking this medicine during pregnancy.

4) Is this medicine habit forming?

Ans: No, this medicine is not habit forming or addictive. However, one must consult a doctor to know more about its nature.

5) Is Calpol tablet safe for use during breastfeeding?

Ans: No, use of Calpol Tablet is strictly prohibited in lactating mothers. The medicine may cause diarrhoea or skin rashes in infants. If absolutely necessary, lactating mothers must hold from breastfeeding the infant until the medicine is completely eliminated from the body. For case-specific recommendations, consult a doctor.

6) I missed a dosage of Calpol tablet. What do I do?

Ans: In case you have skipped a dosage of Calpol then you should take one as soon as you remember. If it is close to the next dose, then skip the dose. However, ensure that you don’t consume double dose to make up for the missed dose.

7) I accidentally consumed an expired Calpol tablet. What should I do?

Ans: Although it is always recommended to check the expiry date of the medicine before administering it, a single expired dose of Calpol Tablet may not cause any severe side effect. However, it must be noted that the efficacy of the medicine may be affected as an expired tablet will not be as effective in treating the symptoms. Also, in case the patient experiences any discomfort after the consumption of an expired dosage, a doctor must be consulted immediately to seek remedial action.

8) What is Calpol Tablet used for?

Ans : It is an analgesic drug that is primarily used to treat mild pain including headache, toothache, menstrual pain, etc. It may also be used to relieve fever and symptoms of osteoarthritis.

9) What is Calpol Tablet to treat?

Ans : It is primarily used to relieve mild fever and mild pain including headache, toothache, menstrual pain and pain associated with osteoarthritis.

10) What are the possible side effects of Calpol Tablet?

Ans : It is a safe medicine that does not usually show side effects. However, in certain cases, it may show certain side effects such as nausea, vomiting, pain in abdomen, jaundice, constipation, diarrhoea, indigestion, high blood pressure, flatulence, loss of appetite and liver toxicity.

11)  Should I administer Calpol Tablet before or after having food?

Ans :  Ideally, Calpol Tablet should be consumed with food or milk in order to avoid gastric irritation. Rest, one should follow the doctor’s advice for the same.

12) Is it safe to drive after consuming the Calpol Tablet?

Ans : Yes, it is absolutely safe to drive post-consuming Calpol Tablet. However, in case the patient feels drowsiness or dizziness, he or she must refrain from doing activities that require sheer concentration.

13)  Is Calpol Tablet available as an Over- the- Counter medicine?

Ans : Yes, Calpol Tablet is not an over-the-counter medicine. It does not require a prescription to be dispensed.

14) What are the storage requirements for Calpol Tablet?

Ans :
•    Calpol Tablets should be stored away from direct sunlight and heat.
•    It should be stored in a dry and cool place.
•    The medicine should be kept out of reach of pets and children

15) Can Calpol Tablets be administered to elderly people?

Ans :  It should be administered cautiously in people above the age of 60 years. This is because the medicine poses an increased risk of side effects such as high blood pressure, abdominal pain, etc. in the elderly population.

16) Can I consume alcohol during the course of treatment with Calpol Tablets?

Ans : No, it is not advisable to consume alcohol during the course of treatment with Calpol Tablets. Their interaction may result in adverse effects on liver health.

17) Is Calpol Tablet banned in India?

Ans: No. the medicine is not banned in India. However, it should be taken only after consulting a doctor.

18) Can Calpol Tablet be administered to children and infants?

Ans : It can be administered to children and infants but only after due consultation with a doctor. However, it is better to administer Calpol syrup and paediatric drops to children and infants rather than tablets.

19) Can Calpol Tablet be used to treat cold?

Ans : The Tablet does not treat cold. However, it can provide relief from the symptoms of cold such as earache, headache and aching joints.

20) Can Calpol Tablet be administered to patients suffering from jaundice?

Ans : No. Since the tablet shows harmful effects on the liver, it should be administered to people suffering from liver diseases such as jaundice and hepatitis.

21) Is Calpol Tablet safe to consume?

Ans: It is safe to be consumed only as long as it is administered in accordance with the prescription of a doctor.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

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