Cefpodoxime: Uses, Side Effects and Dosage

Cefpodoxime falls into the category of antibiotics. More specifically, it is an oral, third-generation cephalosporin drug. Also, the drug is mostly active against all types of Gram-positive and Gram-negative organisms. The drug is generally used to treat cases such as pharyngitis, sinusitis and also gonorrhea.

Cefpodoxime Composition and Nature:

Each film-coated tablet of the drug contains 260.9 mg of cefpodoxime proxetil which is almost equivalent to 200 mg of cefpodoxime.

Also, the drug contains 30 mg of lactose monohydrate and 2.43 mg of sunset yellow FCF. Cefpodoxime falls in the category of antibiotics.

Cefpodoxime Uses and Benefits:

  • The drug is most commonly used to treat a wide variety of common bacterial infections. At the most preliminary level, the drug works by stopping up the potential growth of bacteria.
  • The drug works only against bacterial transgressions. It will not have any effect on viral infections such as common cold and flu.
  • Also, Cefpodoxime is used to treat cases such as pharyngitis, sinusitis and also gonorrhea.
  • The drug is also applied in cases involving bacterial infections in the urinary tract and transgressions in the airway tubes leading to the lungs.
  • Pneumonia and infections in the skin, ear etc. are also treated by the drug.

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Cefpodoxime Side Effects:

The most common side effects of Cefpodoxime may include certain allergic reactions such as difficulty in breathing, swelling of the face, lips, tongue or even the throat.

Apart from these, other side effects may include diarrhea that is fluid or bloody, vaginal itching or irritation, unusual bleeding, wheezing, coughing, tautness of the chest, hyperactive heartbeats, conventional convulsions, and prospective jaundice, enhanced degree of thirst and loss of normal appetite.

Apart from these, other side effects may include pale or amber skin, sore throat, potential headache, blistering, red skin rash, blistering. Also, there may be less serious or psychological effects such as stuffy nose, nauseating sensations, back pain, instances of muscle pain, anxiety and considerable degrees of hypertension, diaper rash in infants etc.

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Cefpodoxime Dosage:

Most importantly, the drug should be taken as prescribed by the doctor concerned.

Apart from that, one may follow the instructions on the prescription label. The medicine should be taken with a full glass of water. The pill should be taken with food whereas the liquid form may be taken without food.

One should take the tablet for the exact duration as prescribed by the doctor concerned. The tablets should be stored at room temperature and away from any hint of moisture, light, and heat.

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How Cefpodoxime Works?

Cefpodoxime falls into the category of antibiotics. More specifically, it is an oral, third-generation cephalosporin drug

At the most preliminary level, the drug works by stopping up the potential growth of bacteria. Specifically speaking, cefpodoxime proxetil is converted to its more active form, cefpodoxime, in the body. Like most cephalosporin, it works by stopping bacteria from multiplying by preventing it from forming the walls that surround them.

The walls are necessary in order to protect the bacteria from any inapt ambiance and bind the cell together. Importantly enough, the drug provides a potent shield against many such bacteria.

Precautions and Warnings Related To Cefpodoxime:

First and foremost, it must be underscored that the usage of the drug may cause certain adverse reactions in patients with a history of penicillin allergy. Equally importantly, in cases of liquid cefpodoxime, the child should be immediately taken to the doctor if his or her condition does not improve.

Apart from these, it is to be noted that with the usage of the drug bacterial or even fungal overgrowth of non-vulnerable organisms may grow with prolonged or repeated therapy.

One should reduce the dosage by fifty percent if Creatinine Clearance is ten to thirty ml. If the Creatinine Clearance is lower than ten ml, one should reduce the dosage by seventy-five percent. It is to be kept in mind that high dosages of the drug may cause central nervous system toxicity.

Also, it is important to keep in mind that cefpodoxime is excreted into breast milk in relatively low concentrations; therefore, the drug is generally not recommended if one is breastfeeding. Although, research has not shown any risk for usage of the drug in pregnancy.

Most importantly, one should not start on a new medicine without the professional consent of a doctor.

Cefpodoxime Substitutes:

The following may be taken as substitutes/alternatives to the drug:

  • Augmentin
  • Bactrim
  • Vantin
  • Duricef
  • Cedax
  • Cipro
  • Keflex
  • Penicillin

Cefpodoxime Interactions:

Generally speaking, antibiotic medications are known for causing diarrhea which may be a signal of a new infection altogether. If one has diarrhea that is fluid or has blood, one should consult the doctor straight away. Usage of any medicine to stop diarrhea without the prescription of the doctor concerned is strictly not recommended.

So far as cefpodoxime is concerned, before taking this drug, one should inform the doctor if he or she is using any of the following drugs:

  • Lithium (Lithobid)
  • Probenecid (Benemid)
  • Methotrexate (Rheumatrex, Trexall)
  • Any kind of antiviral drugs such as adefovir, foscarnet or cidofovir.
  • Any kind of cancer medicines such as carmustine, ifosfamide, tretinoin, streptozocin, plicamycin, oxaliplatin, aldesleukin etc.
  • Diuretics such as furosemide, metolazone, torsemide, bumetanide, indapamide among others.
  • Any kind of medicine that mitigates stomach acid such as an antacid, or cimetidine, famotidine, omeprazole, ranitidine and various others.
  • Medicines used to prevent organ transplant rejection such as tacrolimus or sirolimus.
  • Medicines used to treat ulcerative colitis such as mesalamine, sulfasalazine, and various others.
  • Pain or instances of arthritis medications such as aspirin, acetaminophen, diclofenac, ibuprofen, indomethacin, naproxen and various others.

The list is by no means complete and there may be various others that may interact with the drug. Generally speaking, one should tell the doctor about all the over the counter medications one uses such as minerals, vitamins, herbal products and various other pills suggested by other doctors.

Most importantly, one should not start on a new medicine without the professional consent of a doctor.

Frequently Asked Questions (FAQs)

1) Is cefpodoxime safe to use?

Ans: Generally speaking, the drug is safe to use under prescribed conditions and for the prescribed duration according to the doctoral advice.

2) Is cefpodoxime a steroid?

Ans: Cefpodoxime is not a steroid. It is strictly an antibiotic that belongs to the group of cephalosporins.

3) Can I take cefpodoxime with Ibuprofen?

Ans: Since no analysis has shown any interaction between the two drugs, cefpodoxime may be taken with ibuprofen.

4) Does cefpodoxime cover enterococcus?

Ans: No, cefpodoxime does not cover enterococcus.

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Last updated on : 12-04-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

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