Dolo Tablet: Uses, Side Effects and Dosage

Dolo is the most commonly used pain reliever. It acts against mild to moderate pain.

Dolo is one of the most used analgesic (pain reliever) and antipyretic (fever reducer) drug. This medicine contains a non-opioid compound that acts against pain. It is available in different strengths. It is manufactured by Micro Labs Limited and is available over-the-counter.

Composition and Nature of Dolo Tablet:

The main active ingredient in the tablet is Acetaminophen/Paracetamol. The concentration of Acetaminophen varies according to the strength of the tablet. The various strengths in which Dolo is available are Dolo 500mg, Dolo 650mg , and Dolo 1000mg as tablets.

Uses of Dolo Tablet:

The most important uses of Dolo are:

  • Temporary relief from fever
  • Headaches including a migraine
  • Mild to moderate pain in the muscles
  • Mild to moderate pain in the joints caused by arthritis
  • Menstrual cramps
  • Treatment of pain and fever after the vaccine is administered
  • Tooth pain and other dental complications leading to fever
  • Ear pain

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Side Effects of Dolo Tablet:

The side-effects of Dolo are possible but do not always occur. Some of them can be rare, yet may lead to drastic outcomes. Upon observing any of the side-effects, a doctor must be consulted.

The most common side-effects of Dolo are:

  • Shortness of breath
  • Allergic reactions like swelling of lips and face
  • Reddening of the skin
  • Skin Rashes
  • Damage to the liver
  • Mouth Ulcers
  • Stomach ulcers
  • Nausea or vomiting
  • Sick feeling
  • Anemia
  • Unusual bruising
  • Fatigue

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Dolo Dosage:

The dosage and duration prescribed by the doctor must be followed. This tablet should be taken orally and must be swallowed whole. You should not chew, crush or break the tablet. It can be taken along with or without meals, but the time of consumption should be maintained throughout the course of the tablet. In case you experience nausea, take the tablet after meals.

The dosage prescribed by the doctor may vary according to various factors such as age, body weight, medical condition and the intensity of the symptoms. In most cases, Dolo is prescribed as a regular course, but the doctor will indicate to take it only when required, such as in case of persisting pain or intermittent fever.

When prescribed for the treatment of high-fever, the tablet is generally consumed once in four hours. In case you miss a dose, take it as soon as you remember. If the timing is close to your next dose, skip the missed dose and consume the next scheduled dose. Never overdose on the tablet. Overdose may lead to adverse effects.

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How Dolo Works?

The analgesic activity of Acetaminophen is carried out by blocking the synthesis of prostaglandins and by reducing their concentration in the brain. Prostaglandins are the chemical messengers that are responsible for the feeling of pain and inflammation.

The antipyretic activity of Acetaminophen is carried out by blocking the synthesis of Cyclooxygenase-1 and Cyclooxygenase-2 in the central nervous system that induces fever.

The effect of the medication is seen one hour after consumption and it lasts for up to six hours.

Precautions and Warnings Related To Dolo Tablet:

The following are the precautions that have to be followed for the duration of consumption of Dolo:

  • Consumption of alcohol should be avoided while taking Dolo as the combination of Dolo with Alcohol can damage the liver. Do not take Dolo if you consume alcohol every day.
  • Dolo should be taken with caution by people who suffer from renal diseases or conditions. Adjustment of dosage may be necessary.
  • Dolo is not recommended for people with an active liver disease or those in the advanced stage of any liver disease. For patients with a mild liver disease, dose adjustments may be necessary.
  • Dolo is not recommended for people who are allergic to Acetaminophen or have a history of the same.
  • Caution should be ensured by people who are hypersensitive.
  • Dosage adjustment may be necessary for people who have frequent mouth ulcers.
  • Dolo is not recommended for people who suffer from severe malnutrition

Some health conditions can make you more susceptible to the side effects of the drug. While prescribing the drug, discuss all pre-existing conditions and disorders with your doctor.

Substitutes of Dolo Tablet:

The following medications have the same composition and functions of Dolo and hence can be used as a substitute:

  • Glenpar Tablet by Glenmark Pharmaceuticals
  • Paracetamol Tablet by Novartis India Limited
  • Malidens Tablet by Abbott Healthcare Private Limited
  • Pyremol Tablet by Alembic Limited
  • Volini Duo Tablet by Ranbaxy Laboratories
  • Calpol by Glaxo SmithKline Pharmaceuticals
  • Fepanil by Veritaz Healthcare Limited
  • P Tablet by Apex Laboratories Private Limited
  • Xykaa Rapid by Troikaa Pharmaceuticals
  • Pyrigesic Tablet by East India Pharmaceuticals

Dolo Tablet Interactions:

Paracetamol interacts with certain drugs. While some interactions may lead to the increased risk of side-effects, some may weaken the strength of Paracetamol.

Dolo interacts with the following drugs:

  • Prilocaine
  • Ketoconazole
  • Teriflunomide
  • Leflunomide
  • Juxtapid mipomersen

Dolo also interacts with certain laboratory tests and may lead to false positive results and readings. All the drugs consumed regularly or otherwise should be discussed with your doctor while prescription. This includes supplements and herbal medicines.


1) Can I purchase Dolo without a prescription?

Ans: Yes . Dolo is an over-the-counter drug and can be purchased without a doctors’ prescription.

2) Is Dolo addictive or habit forming?

Ans: No. Dolo is not addictive. All addictive drugs are classified under Schedule H or Schedule X in India. Read the content on the product’s packaging to know more about the classification and the type of your drug.

3) Can I drive after taking Dolo?

Ans: Dolo does not cause dizziness or drowsiness. In case you experience the same, do not drive.

4) Can Dolo be taken during pregnancy?

Ans: Yes. Dolo is safe to consume during pregnancy. No reports of harm to the fetus have been observed.

5) Can Dolo be taken for sports related injury and pain?

Ans: Dolo can be taken for any kind of pain only for short-term relief. Do consult a doctor who will prescribe the right analgesic based on the nature of pain.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

User Comments (1)


Max Sadile

Sat Jul 13 2019

Bought a DOLO NAT tablet which contain MGCl -250 mg, U. Tormen. -250 ng, Pali BrAzil - 100 mg, Rosa Canina - 50 mg,Hara Diablo -50 mg and Meto carb -100mg. Is this tablet same as aforementioned.


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