Duphaston Tablet: Uses, Side Effects, Dosages & Price

Duphaston Tablet is an artificial substitute for progesterone and acts similar to the female hormone in the body. It is used for treating medical ailments caused due to the lack of hormones. This steroidal progestin works by reducing the growth of the endometrium in the body.

Nature Artificial hormone (Progesterone)
Composition Dydrogesterone
Uses Endometriosis, Premenstrual syndrome, Dysfunctional uterine bleeding, Menstrual abnormalities, Habitual abortion, Hormone replacement therapy, Infertility due to luteal deficiency, Threatened abortion.
Side effects Nausea, Abdominal pain, Hives, Drowsiness, Dizziness, Headache , Difficulty in urinating, Mood swings, Rash, Dry Mouth, Indigestion, Diarrhea , Vomiting, Cough , Breast pain, and Depression.
Precautions Abnormal vaginal bleeding, Pregnancy, Breastfeeding, Driving, and Liver disease.
Duphaston Tablet

Uses and Benefits of Duphaston:

Duphaston Tablet can be used for the treatment of the following conditions:

  • Menstrual Cramps
  • infertility due to luteal insufficiency
  • Post-menopausal conditions
  • Endometriosis
  • Internal Uterine Bleeding
  • Amenorrhea
  • Secondary amenorrhoea
  • Abnormal vaginal bleeding
  • Hormone Replacement Treatment
  • Pre-Menstrual disorder
  • Infertility in Women
  • Dysfunctional uterine bleeding and abnormal
  • Hormone replacement therapy
  • Abortion
  • Miscarriage
  • Painful menstrual cycle
  • Secondary amenorrhea
  • Painful menses
  • Weakening of bones

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Side effects of Duphaston:

It may interact with some substances or medical conditions and exhibit certain side effects. Some of the reaction that may occur while administering Duphaston Tablets are:

  • Pain in the Abdomen
  • Nausea
  • Unusual Weight Gain
  • Depression
  • Liver Problems
  • Pain in the Breasts
  • Missed menstrual cycle
  • Heavy Menstrual Flow
  • Skin Allergies
  • Weakness

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Common Dosage of Duphaston:

The dosage of this medicine is generally based on

  • History of drug reaction/ allergy
  • Severity of disease
  • Reaction to the first dose
  • A medical condition of the patient/ health history
  • Patients with liver or kidney disease should consult the doctor before consuming the tablet

It should be taken at a fixed time and duration as advised by the doctor. The tablet has to be swallowed whole, and should not be broken, crushed or chewed. It is advised to continue the advised course of the medicine and not to stop it once the patient feels better. It is advisable that the tablet should be consumed after meals. It is likely to take half-an-hour before the medicine starts showing its effect. The effect of the drug may last for up to 6 hours post the consumption of the drug.

  • Missed Dose : If the patient missed a dose of this medicine, it is advisable to take it as soon as it is remembered. But if it’s almost time to take the next dose, it is recommended to skip the missed dose and take the next dose as per schedule.
  • Overdose : In case the patient suspects an overdose of the medicine, it is advised to seek immediate medical attention.

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Composition and Nature of Duphaston:

Duphaston is an artificial Progestin which acts as an alternative for naturally formed progesterone in a woman's body. This is a substitute drug for the female hormone, and thus it is absolutely necessary to consult a doctor before using this drug. This medicine should only be taken under the supervision and prescription of a doctor.

Precautions and Warnings - When to Duphaston Tablet?

  • If the patient is allergic to any ingredients of this medicine, then it is important to inform the doctor immediately.
  • Patients should refrain from consuming alcohol while taking Duphaston tablet.
  • It is safe to consume for women who are pregnant, planning to get pregnant, or breastfeeding.
  • Driving after taking this tablet is not advised, as it could reduce alertness and cause dizziness . As an extension, the use of heavy machinery should also be avoided for the same reasons.
  • Patients with breast cancer must strictly avoid the consumption of this tablet.
  • Patients suffering from episodes of depression should exercise caution while consuming this tablet.
  • People with kidney problems and liver-related ailments must exercise caution while administering this drug. It is advisable to consult a doctor before administering Duphaston for an appropriate alternative or dose adjustment if needed.
  • The use of this tablet may cause loss of vision as the flow of blood is blocked from the retina to the heart. It is very important to consult a doctor before taking it.
  • It may not be safe for long-term use as it may lead to dangerously low levels of phosphate in the blood. A doctor must be consulted for ascertaining the appropriate dose of this medicine.
  • It is advisable not to take this tablet alongside steroids.

Substitutes for Duphaston:

Jigest 10mg can be an alternative option for Duphaston Tablet.

Duphaston Interactions with Other Drugs:

Interactions with Medicines:

It is not recommended to be taken with medicines listed below as it may cause reaction.

  • Griseofulvin
  • Carbamazepine
  • Phenobarbital
  • Nevirapine
  • Phenytoin
  • Rifampicin
  • Ritonavir

It is always advisable to inform the doctor about pre-existing medications in order to avoid the occurrence of ill effects.

Interaction with Alcohol:

It is not recommended to consume alcohol while administering this tablet as it may cause adverse effects.

Duphaston Tablet Price in India:

Quantity of the medicine Price (INR)
10 tablet in a strip 519.67

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How Duphaston Tablet Works?

Duphaston Tablet is basically a synthetic form of female hormone namely, progesterone which helps to regulate the balance of hormones in the body. It stimulates the lining of the uterus to prepare for pregnancy or protects an existing pregnancy. This drug also helps in hormone replacement treatment in women and prevents unprompted abortion.

How to Use Duphaston?

It is advisable to take Duphaston before or after having a meal. It is suggested to take this medicine exactly in the dose and duration as advised by the doctor.

When is Duphaston prescribed?

This drug is prescribed to treat and prevent conditions such as:

  • Endometriosis : Duphaston is very effective in treating menstrual irregularities.
  • Amenorrhoea: This drug is very helpful in the treatment of the condition where menstrual cycle stops in the absence of menopause or pregnancy.
  • Dysmenorrhea: relieves pain and cramps during a menstrual cycle.
  • Uterine bleeding: It is effective in treating abnormal or irregular uterine bleeding in the absence of any recognizable pelvic pathology.
  • Hormone replacement therapy (HRT)
  • Menstrual abnormalities

Is Duphaston Banned In India?

No, the medicine is not banned in India. The drug falls under the category of schedule “H” drugs and therefore can be purchased from a medical store after showing the doctor’s prescription.

Medicine that should not be taken with Duphaston Tablet:

Duphaston tablet is not recommended to be taken with medicines listed below as it may cause reaction.

  • Nevirapine
  • Phenytoin
  • Rifampicin
  • Griseofulvin
  • Carbamazepine
  • Phenobarbital
  • Ritonavir

How to Store Duphaston?

  • It is advised to store this drug in a cool and dry place.
  • It is not recommended to freeze or refrigerate the tablet.
  • It should be kept away from the reach of the children and pets.

Duphaston should be taken before and after food?

The medicine can be consumed before or after food, as advised by the doctor.

Frequently Asked Questions (FAQs):

1) Is Duphaston an alternate for female Progesterone?

Ans: Duphaston is artificially obtained Progesterone which functions exactly similar to naturally formed progesterone in the woman's body.

2) Can Duphaston cause irregular menstruation?

Ans: Yes, the use of this drug may cause irregular menstruation. Some of the common reaction caused by administering this drug is missed menstruation, unusual and heavy menstrual bleeding, abdominal pain, etc. Please consult your gynecologistif you experience any unusual symptoms while using this drug.

3) Is it safe to consume alcohol while administering Duphaston?

Ans: Patients are advised not to drink alcohol as it may induce excessive sleepiness or reduce the efficacy of the drug in some cases. Thus, it is suggested to refrain from consuming alcohol while administering Duphaston.

4) Does Duphaston provide relief from the cold?

Ans: No, Duphaston does not provide relief from cold . This medicine is meant for treating ailments such as infertility in women, abnormal periods, menstrual cramps, etc.

5) What should be done when an expired Duphaston is consumed?

Ans: An expired Duphaston dose may not cause any serious harm to your body. But feel free to consult your doctor to ensure safety. It is recommended to check the expiry date before consuming any medicine.

6) What should be done in case a dose of Duphaston is missed?

Ans: If a dose of Duphaston is missed, it should be consumed as soon as possible. But if it is coinciding with the time of the next dosage then it is better to skip the earlier dose.

7) Is it safe to drive while taking Duphaston medication?

Ans: Generally, Duphaston does not induce dizziness and drowsiness, but it is advisable to consult your doctor about this.

8) What should be done when more than the prescribed dose of Duphaston is consumed?

Ans: In case you have taken above the prescribed dose of Duphaston you should consult your doctor immediately for remedial action because this might cause severe side effects.

9) What are the side effects of Duphaston tablet?

Ans: Listed below are some of the side effects that may occur while administering Duphaston tablet:

  • Unusual Weight gain
  • Depression
  • Missed Menstruation
  • uneven and Heavy Menstrual Flow
  • Skin Allergies
  • Liver Problems
  • Pain in Breasts
  • Weakness
  • Pain in the Abdomen
  • Nausea
  • Pain in the Abdomen
  • Nausea

10) What is Duphaston used to treat?

Ans: This tablet is used to treat endometriosis, premenstrual syndrome, menstrual abnormalities, dysmenorrhea, hormone replacement therapy, dysfunctional uterine bleeding, infertility due to luteal deficiency, susceptible abortion and more.

11) What is Duphaston tablet used for?

Ans: Duphaston is used to treat and prevent conditions such as

  • Internal Uterine Bleeding
  • Amenorrhea
  • Secondary amenorrhoea
  • Endometriosis
  • Abnormal vaginal bleeding
  • Treating Menstrual Cramps
  • Infertility due to luteal insufficiency
  • Post-menopausal conditions
  • Dysfunctional uterine bleeding and abnormal
  • Hormone replacement therapy
  • Miscarriage
  • Painful menstrual cycle
  • Secondary amenorrhea
  • Painful menses
  • Irregular Periods
  • Hormone Replacement Treatment
  • Pre-Menstrual disorder
  • infertility in Women.
  • Weakening of bones

12) What are the contraindications associated with the consumption of Duphaston?

Ans: Duphaston tablet is not recommended to be taken by patients suffering from the following conditions:

  • Brain cancer
  • Breast cancer
  • Liver dysfunction
  • Patients who are not at any risk of abortion
  • Stroke
  • Breastfeeding Mothers
  • Hypersensitivity
  • Advanced pregnancy
  • Blood clots disorder
  • Undiagnosed abnormal vaginal bleeding

13) What are the appropriate storage requirements for Duphaston tablet?

Ans: Following are the appropriate storage requirements for Duphaston tablet:

  • Keep it in a cool and dry place.
  • Do not refrigerate or freeze.
  • Keep it away from the reach of children
  • Keep it away from the reach of pets.

14) What medicine should not be taken with Duphaston tablet?

Ans: It is not recommended to be taken with the following medicines as it may cause unwanted reaction:

  • Nevirapine
  • Phenytoin
  • Rifampicin
  • Ritonavir
  • Griseofulvin
  • Carbamazepine
  • Phenobarbital

15) Can Duphaston Delay Period?

Ans: It is composed of Dydrogesterone which is a synthetic progestational hormone. It helps to regulate the menstrual cycle and balance the level of these hormones in the body. The medicine tends to regulate the menstural cycle and cannot lead to a delay in the periods.  A woman administering this medicine may skip her periods only due to hormonal imbalance in the body or pregnancy.

16) What is the role of Duphaston in pregnancy?

Ans: It comprises of a hormone called dydrogesterone which is a synthetic variant of the female sex hormone progesterone. This medicine may be advised to women trying to conceive and have a deficiency of progesterone specifically during the luteal phase of the menstrual cycle. Once the woman has conceived the levels of progesterone rise to facilitate the process of pregnancy. This medicine may be advised to maintain these levels during pregnancy.

An overdose of progesterone may lead several side effects such as the death of the developing fetus, spontaneous abortion (in the first 3 months of the gestation period), birth defects in babies such as heart defects and cleft palate, masculinisation of a female fetus (such as unwanted hair on face). During pregnancy, a woman must avoid the excessive consumption of it.

17) How to take Duphaston to regulate periods?

Ans: The medicine is usually prescribed to patients whose periods are irregular. The medicine may also be advised to patients suffering from amenorrhoea. Amenorrhoea is a condition where a female does not get her periods even after reaching puberty.

18) Can Bleeding Occur While Taking Duphaston?

Ans: No, the medicine may not induce bleeding. It is advised to stop abnormal bleeding from the uterus, unexpected vaginal bleeding or spotting.

19) What Are Signs of Low Progesterone in Pregnancy?

Ans: Some of the symptoms associated with the low progesterone levels during pregnancy include -

  • Abdominal pain
  • Spotting
  • Low blood sugar levels
  • Tenderness in breasts
  • Fatigue
  • Vaginal dryness

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

User Comments (2)



Fri Jun 21 2019

I've used Duphaston from the 03rd June to the 16th June, I started the treatment while spotting but I am now on a very heavy flow since the 17th June... Is this normal?


Angel Emeetai

Tue Jul 09 2019

Ithink you don't need to worry me too took dophaston medicine at the June my periods had over delayed up to 50 days in a circle then later it cake with flow of 5 days and plus2 last days in spotting totaling 7 days coz the homones are tying to get balanced possibly I'm not amedical person I'm just sharing also my experience


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