Duvadilan 10 MG Tablet : Uses, Side Effects, Composition & Dosages

Manufactured and marketed in India by Abbot India Limited, Duvadilan is a prescription medicine that belongs to the class of drugs known as ‘peripheral vasodilator’. The medicine contains Isoxsuprine as its active ingredient. Duvadilan is available in market in form of tablets, capsules and injections.

Duvadilan is primarily used to widen the blood vessels to treat poor blood circulation. It is prescribed to treat peripheral vascular diseases such as Buerger’s Disease (inflammation of small blood vessels in the legs, leading to gangrene if untreated), Raynaud’s Disease (numbness in cold temperatures or due to extreme stress, leading to vasospasms) and Arteriosclerosis.

Duvadilan 10 MG Tablet

Duvadilan 10 MG Tablet Composition and Nature:

Duvadilan is a medicine that belongs to the class of drugs known as ‘peripheral vasodilators’. Each tablet contains 10 mg of Isoxsuprine as the active ingredient. Depending upon the variant, the concentration of Isoxsuprine may vary.

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Duvadilan 10 MG Tablet Uses & Benefits:

Duvadilan is a peripheral vasodilator that is primarily used to widen the blood vessels to increase the blood flow. It is used to treat Peripheral Vascular Diseases. These are the circulatory conditions in which narrowed blood vessels result in poor circulation of the blood. The vessels are narrowed due to fat deposition or calcium build up in the walls of the arteries. Buerger’s Disease, Raynaud’s Disease and Atherosclerosis are a few types of peripheral vascular diseases.

Duvadilan may also be used to treat a few other conditions such as:

  • Premature labour pain
  • Threatened abortion
  • Night cramps

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Duvadilan 10 MG Tablet Side Effects:

Duvadilan is a safe drug to consume. However, in certain cases, it may show some side effects. The side effects include:

  • Dizziness
  • Abdominal pain
  • Flushing
  • Nervousness
  • Weakness
  • Irregular heartbeat

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Duvadilan 10 MG Tablet Dosage:

The patient should administer Duvadilan Tablets in accordance with the instructions prescribed by the doctor. The dosage may vary with the severity of the ailment to be treated. A few other factors that help in deciding the dosage are the BMI of the patient, age of the patient and other underlying health concerns.

  • Missed Dosage: Patients should take the missed dose as soon as it is remembered. However, it is advisable not to take the missed dose if it is almost time for the next dose.
  • Overdose: Overdose may show serious side effects or drug toxicity and thus one should refrain from taking an overdose. However, if an overdose is suspected, one must rush to a doctor to seek immediate medical attention.

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How Duvadilan 10 MG Tablet works?

Duvadilan is a peripheral vasodilator that contains Isoxsuprine as its active ingredient. The medicine works as a beta-adrenergic receptor agonist. It dilates the blood vessels and relaxes uterine and vascular smooth muscle to increase the blood flow in the peripheral parts of the body.

How to Use Duvadilan Tablet?

Duvadilan Tablets should be consumed as per the prescription of the doctor or the patient should follow the directions prescribed on the label. One must not increase or decrease the dosage without consulting a doctor. It is advised to swallow the tablet as a whole, without chewing, crushing or breaking it.

The absorption of Duvadilan is not influenced by food and thus can be consumed with or without food, as advised by the doctor. However, to prevent any undesirable effect, especially in patients suffering from gastric disorders, it should be taken with food or immediately after food.

How is Duvadilan prescribed?

Duvadilan is a peripheral vasodilator drug that is primarily used to widen the blood vessels and treat poor blood circulation. Doctors usually prescribe this medicine to treat Peripheral Vascular Diseases such as Buerger’s Disease, Raynaud’s Disease and Atherosclerosis.

It may also be prescribed to treat premature labour pain and night cramps. The medicine may also be used in patients with a past history of miscarriages to significantly reduce the chances of abortion.

Duvadilan 10 MG Tablet Related Warnings / Precautions

A few points that should be taken into consideration before consuming Duvadilan 100 mg Tablets are:

  • Bleeding Disorder: Duvadilan Tablet should never be administered by patients suffering from bleeding disorders, as this may worsen the condition of the patient. Hence, the patients are advised to discuss their medical conditions with the doctor. Appropriate dose adjustment may be required in such cases.
  • Breastfeeding: Duvadilan may mix with the blood and affect the quality of breast milk. To avoid the occurrence of any harmful effects on the health of the infant, the use of this medicine by nursing mothers is strictly prohibited.
  • Paediatrics: As the safety and effectiveness of Duvadilan tablet have not been established in case of children and infants, it should never be administered to them.
  • Dizziness: Use of Duvadilan Tablets may cause severe dizziness or drowsiness. It is thus advised that the patients should refrain from driving, operating heavy machinery or other activities that require mental alertness.
  • Hypersensitivity: Patients with known hypersensitivity to any of the constituents of Duvadilan should avoid taking this medicine.

Duvadilan 10 MG Tablet Substitutes:

Duvadilan substitutes and their manufacturers are noted below –

  • Gestakind 10 mg Tablet is sold by Mankind Pharma Limited.
  • Adilan 10 mg Tablet is marketed by Albert David Limited.
  • Suprox 10 mg Tablet by Ind Swift Laboratories Limited.
  • Isolan 10 mg Tablet by Macmillon Pharmaceuticals.
  • Tidilan 10 mg Tablet by Juggat Pharma.
  • Vasodilan 10 mg Tablet by Lark Laboratories.
  • Pregnin & Pregnin Retard 10 mg Tablet by Overseas Healthcare Private Limited.
  • Adilin 10 mg Tablet by Lincoln Pharmaceuticals Limited.
  • Susox 10 mg Tablet by Rekvina Laboratories Limited.
  • Uterest 10 mg Tablet by Serum Institute of India Limited.
  • Udilan 10 mg Tablet by Troikaa Pharmaceuticals Limited.
  • Isoxlan 10 mg Tablet by Colinz Laboratories Limited.
  • Gidilan 10 mg Tablet by Prayas Pharmaceuticals.
  • Isoprix 10 mg Tablet by Dial Pharmaceuticals Private Limited.
  • Pridilan 10 mg Tablet by Gujrat Terce Laboratories Limited.

Duvadilan 10 MG Tablet Interactions

Interactions with drugs

Mixing two or more medicines may change how the drug works and may increase the risk of side-effects. A few drugs that may interact negatively with Duvadilan are:

  • Tizanidine
  • Antihypertensives
  • Antipsychotics

Interaction with alcohol

Interaction of Duvadilan 10 mg Tablets with alcohol is not known. However, when taken along with alcohol, the medicine may not show the desired results. Hence, it is advisable to discontinue the consumption of alcohol during the course of treatment.

Disease Interactions

Duvadilan should not be consumed in case of:

  • Bleeding Disorders

Variants of Duvadilan 10 MG Tablet:

Variants of Duvadilan are:

  • Duvadilan 10 mg Tablet
  • Duvadilan Retard 40 mg Capsule SR
  • Duvadilan IM/IV 5 mg Injection

Medicines That Should Not be taken with Duvadilan 10 MG Tablet:

Taking Duvadilan Tablet in combination with other over the counter medicines, herbal medicines or vitamin supplements may increase the risk of side effects. A few drugs that should never be taken with Duvadilan Tablets are:

  • Tizanidine (Severe)
  • Antihypertensives (Moderate)
  • Antipsychotics (Moderate)

Duvadilan Tablet Price in India:

Variant Price (in INR) Quantity
Duvadilan 10 mg Tablet 137.88 50 Tablets

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How to Store Duvadilan 10 MG Tablet?

Duvadilan Tablets should be stored in a cool and dry place away from direct heat and sunlight. The packaging of this medicine must be kept intact in order to maintain its effect when being administered. One must keep the medicine away from the reach of children and pets.

Duvadilan 10 MG Tablet FAQs

1) What is Isoxsuprine hydrochloride or Duvadilan?

Ans: Duvadilan causes the widening of blood vessels and causes relaxation of the uterine and smooth muscles. It is a vasodilator.

2) What is Duvadilan used for?

Ans: Duvadilan 10 mg tablets are given orally for treating peripheral vascular disease (PVD) or peripheral artery disease (PAD), which mostly affects the hands and legs.

Injectable Duvadilan is mainly used for premature labor.

3) What is the treatment cost of Duvadilan?

Ans: Cost depends mainly on two factors – dosage and duration. However by normal standards the therapy is not expensive. The exact per tablet price can be had from the packaging box.

4) Is Duvadilan safe during pregnancy and lactation?

Ans: The Doctor will prescribe Duvadilan only when unavoidable during pregnancy. The Doctor will weigh the risks vis-a-vis the safety of the patient. Duvadilan is not for self-medication.

Duvadilan is safe for use during lactation.

5) What is the effect of Duvadilan on the kidney or the liver?

Ans: Very limited information is available for its use in ailing liver or kidney patients. Your Doctor is the best judge to prescribe Duvadilan after knowing such conditions.

6) Is Duvadilan habit forming?

Ans: No. It is not habit forming. Long-term use is not advisable unless your Doctor thinks it is necessary.

4) What are the possible side effects of Duvadilan?

Ans: Duvadilan is a safe medicine that shows no major side effects. However, it may show certain mild side effects such as dizziness, weakness, pain in abdomen, nervousness, irregular heartbeat and flushing.

5) Can I drive or operate heavy machinery post administering the Duvadilan Tablet?

Ans: No. Duvadilan Tablet has been reported to cause drowsiness and dizziness in certain cases. Hence, it is advised to avoid driving or operating heavy machinery during the duration of this medicine.

6) Can Duvadilan be consumed during pregnancy?

Ans: Yes, Duvadilan can be consumed during pregnancy. In fact, it is prescribed to treat premature labour pain. However, pregnant women should never consume this medicine without consulting a doctor.

7) Can nursing mothers consume Duvadilan?

Ans: Effect of Duvadilan on the quality and quantity of breast milk is not known. Hence, it is advised that the nursing mothers should avoid the use of this medicine. However, for case-specific recommendations, one must consult a doctor.

8) Should Duvadilan be taken with food or without food?

Ans: Absorption of Duvadilan is not influenced by the food. Hence, it can be taken with or without food, as advised by the doctor. However, to minimize the risk of gastric disorder, one should consume this medicine after having a meal.

9) Can I get Duvadilan Tablet without a prescription?

Ans: No. Duvadilan is a prescription medicine that legally requires a prescription to be dispensed.

10) How should Duvadilan be stored?

Ans: Duvadilan should be in a cool and dry place away from direct heat and sunlight. It should be kept away from the reach of children and pets. Also, the packaging of this medicine must be kept intact in order to maintain its effect when being administered.

11) Can I stop taking Duvadilan Tablet if my symptoms are relieved?

Ans: No. You should continue taking Duvadilan Tablet for the specific duration for which the doctor has prescribed the medicine. However, if your symptoms are relieved, you must consult a doctor before discounting the use of this medicine.

12) How does Duvadilan work?

Ans: Duvadilan works as a beta-adrenergic receptor agonist. It dilates the blood vessels and relaxes uterine and vascular smooth muscle to increase the blood flow in the peripheral parts of the body.

13) Is Duvadilan addictive in nature?

Ans: No, Duvadilan is not addictive in nature. Although Duvadilan shows no habit-forming tendency, one should consult a doctor more about the nature of this medicine.

14) I am suffering from haemophilia. Can I consume Duvadilan?

Ans: No, Duvadilan should not be administered by patients suffering from any kind of bleeding disorder. Doing so may worsen the condition of the patient.

15) What medicines should be avoided during the course of treatment with Duvadilan?

Ans: Medicines that should never be consumed with Duvadilan are Tizanidine, Antihypertensives and Antipsychotics.

16) Can I consume alcohol during the course of treatment with Duvadilan?

Ans: Interaction between Duvadilan and alcohol is not known. However, when taken along with alcohol, the medicine may not show the intended results. Hence, it is recommended to discontinue the consumption of alcohol during the course of treatment.

17) What should I do in case I missed a dose of Duvadilan?

Ans: Ideally, you should never miss a dose of Duvadilan. However, if accidentally missed, you should take the missed dose as soon as it is remembered. It is advisable to skip the missed dose if it is almost time for your next dose. Under no circumstances, overdose should be consumed to compensate for the missed dose.

18) What should I do in case I took an extra dose of Duvadilan?

Ans: Ideally, you should always take Duvadilan in accordance with the prescription of the doctor. One should refrain from taking an overdose as it may show serious side effects or drug toxicity. However, if an overdose is taken accidentally, you must rush to a doctor to seek immediate medical attention.

19) Is there any substitute for Duvadilan 10 mg Tablet?

Ans: Yes. A few known substitutes of Duvadilan 10 mg Tablet are:

  • Isolan 10 mg Tablet
  • Tidilan 10 mg Tablet
  • Adilan 10 mg Tablet
  • Uterest 10 mg Tablet
  • Udilan 10 mg Tablet
  • Suprox 10 mg Tablet
  • Adilin 10 mg Tablet
  • Vasodilan 10 mg Tablet
  • Gestakind 10 mg Tablet
  • Susox 10 mg Tablet

20) Can Duvadilan be administered to children?

Ans: No. The safety and effectiveness of Duvadilan tablet have not been established in case of children and infant and hence, it should never be administered to them.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

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