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Gabapin NT 400 MG Tablet: Uses, Side Effects, Composition, Price & Dosages

Gabapin NT 400 mg tablet is an anticonvulsant, used for relieving the symptoms of depression, fits, long-standing pain in the legs and arms. Gabapin NT may also be prescribed for the treatment of peripheral neuropathic pain (pain related to nerve damage). It may also be used during adjunctive therapy in people suffering from partial seizures and epilepsy.

Nature of Gabapin NT 400 MG Tablet: Anticonvulsant
Uses of Gabapin NT 400 MG Tablet: Seizures, hot flashes, restless leg syndrome, post-herpetic neuralgia, nerve pain in adults, epilepsy
Composition of Gabapin NT 400 MG Tablet: Gabapentin and Nortriptyline
Side Effects of Gabapin NT 400 MG Tablet: Dizziness , Constipation , uncontrolled eye movements, hyperactivity, lower back pain, increased appetite
Precautions: People with kidney problems, undergoing dialysis, recent heart attack, thyroid problems, diabetes etc. must exercise caution.

Gabapin NT 400 MG Tablet

Gabapin NT 400 mg tablet also improves the functioning of the brain and treats post-herpetic neuralgia. Gabapin NT tablet is manufactured in India by Intas Pharmaceuticals Ltd.

Uses and Benefits of Gabapin NT:

Gabapin NT falls under the category of anticonvulsant and is primarily used to treat neurological problems like Trigeminal nerve diseases and post-herpetic neuralgia. A few other conditions where the doctor may prescribe Gabapin NT mg tablets are:

  • Depression
  • Post-herpetic neuralgia
  • Adjunctive therapy in the treatment of partial seizures
  • Long-standing pain in legs and arms
  • Fits
  • Bed wetting in children
  • Epilepsy

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Side Effects of Gabapin NT:

Some common side effects associated with the administration of Gabapin NT are -

  • Suicidal thoughts
  • Panic attacks
  • Trouble sleeping (insomnia)
  • Acting aggressive, being angry or violent
  • Acting on dangerous impulses
  • Swelling of your face, lips, throat or tongue
  • Liver problems including jaundice
  • Unusual bruising or bleeding
  • Hyperactivity
  • Other unusual changes in behaviour or mood
  • Changes in behaviour and thinking
  • Attempts to commit suicide
  • Serious depression, anxiety or irritability
  • Feeling agitated or restless
  • Allergic reaction such as skin rash, hives, difficulty breathing, fever
  • Swollen glands that do not go away
  • Severe fatigue or weakness
  • Unexpected muscle pain
  • Frequent infections
  • Lack of coordination, feeling tired or drowsy
  • Viral infection
  • Jerky movements
  • Dizziness, tremors
  • Low blood pressure while standing
  • Headache and irregular fast or heavy heart beats
  • Strange body movements
  • Concentration problems
  • Taste problems
  • Weakness
  • Fatigue
  • Nausea and vomiting
  • Unusual eye movement
  • Swelling, usually of legs and feet
  • Dry mouth, sweating, flushing, constipation
  • Blurred or double vision
  • The decrease in libido and erectile dysfunction
  • Tingling in arms or legs
  • Dilation of pupils
  • Weight gain

Some of the rarely occurring side effects associated with the administration of Gabapin NT  tablets are -

  • Changes in sleep patterns (including nightmares)
  • Feeling excessively happy and hyperactive
  • Numbness
  • Convulsions
  • Increased pressure in the eyes
  • Problem while urinating
  • High blood pressure
  • Sleeplessness

Some rare side effects of Gabapin NT can be listed as follows:

  • Weight loss
  • Abnormal liver function
  • Sensitivity to light
  • Hallucinations (in patients with schizophrenia)
  • Loss of appetite and feeling irritated
  • Intestinal blockage or changes in sexual performance can also occasionally occur
  • Increased transaminase or blood alkaline phosphatase or salivary glands
  • Hair loss

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Common Dosage of Gabapin NT:

For an adult, the usual recommended dose of Gabapin NT is 300-900 grams per day at the beginning which may be gradually be increased to 3600 mg.

  • Missed Dose : A missed dose of Gabapin NT mg must be taken as soon as it is remembered. If it is almost time for the next dose, then the missed dose should be skipped. It is advisable to take the scheduled dose on time. One should not take an extra dose in order to make up for the missed dose.
  • Overdose : Consuming more than the prescribed dosage of Gabapin NT may lead to adverse side effects such as anxiety and restlessness. Gabapin NT should only be administered in the dose as prescribed by the doctor. If an overdose is suspected, immediately consult a doctor.

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Composition & Nature of Gabapin NT:

The composition of Gabapin NT includes Gabapentin (400mg) and Nortriptyline (10mg) as active ingredients. Nortriptyline is an anti-depressant that works towards subsiding pain by blocking the movement of pain signals in the brain and Gabapentin reduces pain by calming the nerve cells.

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Gabapin NT 400 mg tablet Price in India:

Name Manufacturer Price
Gabapin NT 400mg Tablet (15 Tablets) Intas Pharmaceuticals Ltd INR 356

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When Gabapin NT 400 MG Tablet is Prescribed?

Gabapin NT 400 mg tablet is an anticonvulsant drug. It is primarily used for neurological problems like Trigeminal nerve diseases and post-herpetic neuralgia. Doctors may also prescribe Gabapin NT  to manage depression, fits and long-standing pain in arms and legs. Gabapin NT may also be prescribed in Adjunctive therapy for the treatment of partial seizures. Gabapin NT may also be used for epilepsy which is a brain disorder characterized by uncontrolled jerking movements and loss of consciousness.

How to Use Gabapin NT 400 MG Tablet?

It is suggested that patients follow the directions of the doctor or as mentioned on the label of Gabapin NT. The medicine must be swallowed whole. Do not chew, crush or break Gabapin NT 400 MG Tablet before consumption. The patients may consume Gabapin NT with or without food as prescribed by a doctor.

How Gabapin NT 400 MG Tablet Works?

Gabapin NT 400 MG Tablet is a combination of two drugs namely Gabapentin and Nortriptyline. Gabapin NT is an alpha 2 delta ligand which reduces the pain by modulating the activity of calcium in the nerve cells. Nortriptyline is an antidepressant medication that works by increasing the levels of chemical messengers called serotonin and noradrenaline. These messengers inhibit the pain signals that arise in the brain. Both drugs work together to relieve neuropathic pain.

Warnings/Precautions- When to avoid Gabapin NT?

Some important precautions and warnings to follow while administering Gabapin NT 400 mg are as follows:

  • Hypersensitivity: Gabapin NT 400 mg is not recommended for patients with any kind of allergy to anticonvulsant medicines.
  • Kidney Disease: Gabapin NT shows severe side effects in patients with an impaired kidney. It should be used with extra care and caution in patients having a known history of kidney related disorders. Appropriate adjustment to the dose and close monitoring of kidney function are required in such cases.
  • Pregnancy: Use of Gabapin NT 400 in pregnant women should be avoided unless potential benefits outweigh the risks. It is advisable to consult the doctor to analyse the potential risks and benefits.
  • Breastfeeding: This medicine should be avoided by women during their lactation period as it may be passed on to the infant through breast milk and may cause health problems. Therefore, lactating mothers must administer the medicine if deemed absolutely necessary by a doctor.
  • Liver Disease: Gabapin NT shows severe side effects in the patients suffering from liver-related ailments. The medicine should be administered with extra caution in patients having a known history of liver-related disorders. Appropriate adjustment of the dose and close monitoring of liver function may be required in such cases.
  • Skin Reactions: Gabapin NT may cause skin reactions in patients experience from eosinophilia and Systematic Symptoms (DRESS). The treatment may be discontinued after consulting the doctor, if any symptoms such as skin rashes, redness or itching appear.
  • Sedation: Consumption of Gabapin NT may induce dizziness in patients. Therefore, patients are advised not to drive or operate heavy machinery after administering this medicine.
  • Paediatric Use: Gabapin NT should be used with caution in children falling in the age group between three to twelve years. Gabapin NT may cause side effects that affect the central nervous system such as behavioural changes, difficulty in concentration and restlessness.
  • Withdrawal Symptoms: Gabapin NT should not be stopped immediately without informing the doctor as there is a risk of the symptoms and diseases getting repeated. Gradual dose reduction should be made based on the response shown by the patient.

Apart from these Gabapin NT should not be administered to the patients experience from cardiac arrhythmia and acute myocardial infarction.

Substitutes for Gabapin NT:

The substitutes of Gabapin NT are:

  • Pentanerv NT 400 mg Tablets manufactured by Alkem Laboratories Ltd.
  • Acegaba NT 400 mg Tablets manufactured by Emcure Pharmaceuticals Ltd.
  • Doloneuron NT Tablets manufactured by Pulse Pharmaceuticals
  • Biggaba NT Tablets manufactured by Mankind Pharma Ltd.
  • Laregab NT Tablets manufactured by La Renon Healthcare Pvt. Ltd.
  • Arigaba NT Tablets manufactured by Arinna Lifesciences Pvt. Ltd.
  • Gabator NT 400mg Tablets manufactured by Torrent Pharmaceuticals Ltd.
  • Nuromark NT 400mg Tablets manufactured by Unimarck Healthcare Ltd.
  • Adgaba 400mg Tablets manufactured by Bion Therapeutics India Pvt. Ltd.
  • Gabaride NT 400mg Tablets manufactured by Medo Pharma
  • Gabacent NT 400mg Tablets manufactured by Crescent Therapeutics Ltd.
  • Dutam Plus Tablet manufactured by Vivid Biotek Pvt. Ltd.
  • Gabafirst NT 400mg Tablet manufactured by Inizia Healthcare Pvt. Ltd.

Gabapin NT Interaction with Other Drugs:

Consumption of Gabapin NT along with other drugs or in case of certain medical conditions puts the person at risk of drug interaction. Here is the list of possible interactions for Gabapin NT:

Interaction with Diseases

The following list of medical conditions specifies when Gabapin NT should not be administered -

  • Allergy to any of the components (hypersensitivity)
  • Kidney related ailments
  • Nervous system disorder
  • Cardiac arrhythmia and acute myocardial infarction patients

Interaction with alcohol

Consuming alcohol during the administration of Gabapin NT may show adverse effects. It may increase the risk of side-effects and other health conditions.

Interactions with medicine and drugs:

Gabapin NT may interact with the following medicines-

  • Antacids – These medicines help to neutralise stomach acid. The medicines work differently from other acid reducers such as H2 receptor blockers or proton pump inhibitors.
  • Cimetidine – Gabapin NT is used to ulcers of the stomach and intestines and prevent them from recurring. The medicine is often used to treat certain stomach and throat problems caused by excessive stomach acids.
  • Morphine – One of the natural plant alkaloids present in opium and is the prototype opiate. It is used for treating severe pain, pre- and postoperative analgesia, control of pain from angina pectoris or acute myocardial infarction and therapy of pulmonary edema.
  • Hydrocodone – Gabapin NT is used to severe pain in patients who cannot be treated with other medications or treatments.
  • Nabilone – Known as the man-made form of cannabis, this medicine is used to severe nausea, vomiting generally caused by chemotherapy and is used only when other medicines have not produced the desired effects.
  • Fluoxetine – Gabapin NT is used to depression, obsessive-compulsive disorder, eating disorders, panic attacks, etc.
  • Diltiazem – used to high blood pressure and control angina, this medicine belongs to a class of calcium channel blockers. It works by relaxing the blood vessels to help the heart ease blood pumping action.

Medicines that should not be taken with Gabapin NT:

Mixing two or more medicines may change how Gabapin NT works. It also increases the risk of side-effects. It is advisable to inform the doctor about all the on-going drugs, herbal supplements, and vitamins so that the doctor can manage drug interactions.

A few medicines which should not be taken with Gabapin NT tablet are:

  • Antacids
  • Cimetidine
  • Morphine
  • Hydrocodone
  • Nabilone
  • Fluoxetine
  • Diltiazem

Gabapin NT Variants:

Variants of Gabapin NT are:

  • Gabapin NT 400mg Tablet
  • Gabapin NT 100mg Tablet
  • Gabawin NT 75mg Tablet
  • Gabawin NT 50mg Tablet

How to store Gabapin NT?

  • Gabapin NT must be stored below 25 degrees but never at a freezing temperature.
  • Gabapin NT must be kept away from direct heat or sunlight.
  • Gabapin NT must be kept away from the reach of children.
  • It is advised not to keep Gabapin NT at a place from where it can retain moisture like in the bathroom or near the kitchen sink.

FAQs

1) Is it safe to drive or operate heavy machinery after dosing on Gabapin NT 400 MG Tablet?

Ans: Gabapin NT 400 mg tablet have a sedative effect and so driving or operating heavy machinery is not recommended right after dosing on these tablets. If a patient experiences any side effects such as irritation, anxiety, dizziness, and blurred vision, he/she must immediately consult a doctor.

2) Is Gabapin NT addictive?

Ans: No, Gabapin NT is not known to have any habit-forming tendencies. In India, addictive medicines are categorized under schedule H or X and under II-IV in the US. Please check the package to know if Gabapin NT falls under any such category.

3) What are the side effects of Gabapin NT?

Ans: Gabapin NT may show a number of side-effects, ranging from mild to moderate. Some of the most common side-effects associated with the medicine are dizziness, constipation, weight gain, neuralgia, upper respiratory infection, decreased sex drive and ataxia.

4) Is Gabapin NT 400 MG Tablet safe to use?

Ans: Unless benefits outweigh the side-effects, Gabapin NT 400 mg tablet should not be administered. People with kidney/liver-related disorders and pregnant females as well as lactating mothers should avoid Gabapin NT.

5) Is Gabapin NT an antibiotic?

Ans: No, Gabapin NT is not an anticonvulsant. It is used to treat depression, fits, long standing pain in legs and arms. Gabapin NT may also be advised in adjunctive therapy in the treatment of partial seizures and management of postherpetic neuralgia.

6) Should I stop taking Gabapin NT if my symptoms are relieved?

Ans: No, continue it for the specific time for which the doctor has advised 400 MG Tablet or consult a doctor before discontinuing it.

7) Is Gabapin NT a narcotic substance or a steroid?

Ans: Gabapin NT is neither a narcotic substance nor a steroid. It is an anticonvulsant that works towards relaxation of the nerves and blockage of pain signals in the brain by the release of certain chemical messengers like serotonin and noradrenaline.

8) How can one manage weight gain as a result of administering Gabapin NT 400 mg?

Ans: Since the consumption of Gabapin NT 400 mg tablets makes a person feel hungry, it may result in overeating which in turn leads to weight gain. Preventing weight gain is easier with a healthy and balanced diet with controlled portion sizes. It is advisable to avoid high-calorie foods like soft drinks, oily foods, chips, cakes, biscuits, and sweets. Substitute mid-meal cravings with healthy fruits and veggies along with low-calorie foods.

9) Can the use of Gabapin NT affect a patient’s sexual life?

Ans: The consumption of Gabapin NT may affect the sexual life of both men and women. Some of the side effects include low libido, erectile dysfunction, and inability to reach orgasm. Moreover, Gabapin NT may also lead to a decrease in satisfaction and discomfort during intercourse.

10) What is the onset of action of Gabapin NT 400 mg? How long does the medicine take to act?

Ans: Gabapin NT 400 mg tablets may take at least two-three hours to show its effect. When taken as per doctor’s prescription, an improvement may be observed within two weeks of starting the treatment. Depending on the patient’s condition, Gabapin NT may take longer to show effects.

11) Is Gabapin NT a painkiller?

Ans . No, Gabapin NT is not a painkiller. It belongs to a class of medicines called anticonvulsants. It may be prescribed for alleviating neuropathic pain.

12) What is Gabapin NT 100 used for?

Ans. Gabapin NT is used in the treatment, prevention, and controlling symptoms associated with conditions such as:

  • Neuropathic pain related to spinal cord injuries or diabetes
  • Adjuvant therapy in the treatment of epilepsy
  • Post herpetic neuralgia
  • Trigeminal neuralgia
  • Shingles

13) Does Gabapin NT help in the treatment of anxiety?

Ans: No, this medicine is not prescribed to treat anxiety. Gabapin NT belongs to a class of anticonvulsants and is generally advised to treat neuropathic pain.

14) What are the contraindications associated with the consumption of Gabapin NT?

Ans: Listed below are the contraindications associated with the consumption of Gabapin NT:

  • Skin Rash
  • Low Blood Pressure
  • Difficulty in breathing
  • Loss of consciousness
  • Swelling of the lungs, tongue, throat, and lips

15) Can I take Gabapin NT and Nortriptyline at the same time?

Ans: Nortriptyline is one of the active ingredients of Gabapin NT. If a patient administers Nortriptyline along with Gabapin NT it may lead to drug toxicity. It is prescribed to consult a doctor before administering the medicine.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

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