Glyciphage 500 MG Tablet: Uses, Side Effects, Composition, Dosages & Price

Glyciphage 500 MG Tablet falls under the category of antidiabetic agents. These tablets are manufactured by Franco Indian Pharmaceuticals Pvt. Ltd. It is mainly used for the treatment of Type II Diabetes Mellitus and Polycystic Ovary Syndrome. In some conditions, it may also be used to manage cardiovascular diseases, obesity and hypertension. This medicine works by suppressing the amount of glucose produced by the liver thereby lowering the blood sugar level in diabetic patients.

Nature Non-sulfonylureas, Oral Biguanides
Uses Type II Diabetes Mellitus, Polycystic Ovary Syndrome, Heart Disorders, Obesity, Hypertension
Composition Metformin
Side effects Diarrhoea, Stomach pain, Nausea and vomiting, Hypoglycemia, Weakness, Lactic acidosis, Chest Discomfort, Headache, Swollen joints, Heartburn, Running nose
Precautions Pregnancy, Lactation, Hypersensitivity, Bleeding disorders, Kidney diseases, Diarrhea, Vitamin B-12 deficiency, Alcoholism, Stress

Glyciphage 500 MG Tablet

Uses and Benefits of Glyciphage:

The Glyciphage tablet is categorized as an antidiabetic agent that is used in the treatment of the following conditions and symptoms:

  • Type 2 diabetes mellitus: The active ingredient of this medicine is metformin which is an oral antihyperglycemic agent. It increases both hepatic and insulin sensitivity in the liver by controlling basal hepatic glucose production and increasing glucose uptake. It also improves insulin action and glycemic control. In that respect, the addition of metformin improves metabolic control and reduces complexities in type II diabetes.
  • Cardiovascular disease: Due to its anti-inflammatory properties, metformin is useful in treating cardiovascular disease in people with type II diabetes.
  • Polycystic Ovary Syndrome: This medicine is also used for lowering the insulin and blood sugar levels in patients suffering from Polycystic Ovary Syndrome(PCOS). It helps in regulating the menstrual cycle, ovulation and reduces the risk of miscarriage in women.
  • Obesity : Glyciphage can help people in losing weight. This is achieved by reducing the appetite. It may also change the way a patient’s body uses and stores fat. It increases insulin sensitivity that enables the patient to work efficiently. This leads to decreased glucose production and reduced fat deposition in the body. This, in turn, reduces the weight of the person.
  • Hypertension : With an array of cardiovascular problems associated with high insulin levels, Glyciphage also helps in lowering cholesterol, fatty acids and insulin levels when patients experience hypertension.

The Glyciphage 500 MG Tablet may also be used for treating the conditions that are not listed above

Read More: Chymoral Forte Uses | Itch guard Uses | Protinex Uses

Side Effects of Glyciphage:

Apart from the intended effects of this medicine, it may show side effects in some cases. Side effects are unwanted symptoms that can be caused by any medicine including prescription, over-the-counter medicines and herbal supplements.

Patients should seek immediate medical attention if they notice the occurrence of the following side effects:

  • Hypoglycemia
  • Nausea and vomiting
  • Abdominal Pain
  • Diarrhoea
  • Lactic Acidosis
  • Swollen Joints
  • Chest Discomfort
  • Heartburn
  • Bloating
  • Running Nose
  • Weakness
  • Anxiety
  • Palpitation
  • Flatulence
  • Difficulty in urinating
  • Anorexia

Read More: Safi Side Effects | Mucaine Gel Side Effects | Primolut N Side Effects

Common Dosage of Glyciphage:

The patient should administer Glyciphage 500 MG Tablet in accordance with the instructions prescribed by the doctor. Usually, doctors prescribe 0.5 to 2.5 mg per day. However, the dosage may vary with the severity of the ailment to be treated. A few other factors that help decide the dosage are the BMI of the patient, age of the patient and other underlying health concerns.

  • Missed Dose: Patients should take the missed dose as soon as it is remembered. However, it is advisable not to take the missed dose if it is almost time for the next dose.
  • Overdose: Overdosage may show serious side effects or drug toxicity and thus one should refrain from taking an overdose. However, if an overdose is suspected, one must rush to a doctor to seek immediate medical attention.

Read More: Ciplox TZ Dosage | Drotin ds Dosage

Composition and Nature of Glyciphage:

Glyciphage is an anti-diabetic agent that contains Metformin (500 mg) as its active ingredient. It belongs to the category of Non-sulfonylureas and Oral Biguanides. The medicine helps in managing blood sugar level, obesity and cardiovascular diseases.

Read More: Revital Composition | Disprin Composition | Patanjali Hair Oil Composition

Glyciphage 500 MG Tablet Price in India:

Medicine Variant Price(INR) Quantity
Glyciphage 500 MG Tablet 31.48 20 Tablets
Glyciphage SR 500 mg Tablet 19.99 10 Tablets
Glyciphage SR 1gm tablet 38.27 10 Tablets
Glyciphage 250 tablet 9.72 10 Tablets
Glyciphage SR 850 mg tablet 31.87 10 Tablets
Glyciphage 850 tablet 23.06 10 Tablets

Read More: Pantop D Price | Pantop DSR Price

How Glyciphage Works:

Glyciphage tablet is categorized as an anti-diabetic agent that contains Metformin as its active ingredient. It works by decreasing the level of glucose production in the liver. It reduces the intestinal absorption of glucose and increases the body’s sensitivity to insulin.

How to Use Glyciphage?

The medicine should be consumed as per the prescription of the doctor or the patient should follow the directions prescribed on the label. One must not increase or decrease the dosage without consulting the doctor. It is advised to swallow the tablet as a whole, without chewing, crushing or breaking it. Glyciphage 500 MG Tablet should be taken, preferably with food or immediately after food.

When is Glyciphage Tablet Prescribed?

Glyciphage tablet is an antidiabetic agent that is primarily used for relieving the symptoms of Type II Diabetes Mellitus and Polycystic Ovary Syndrome. Doctors may also prescribe this medicine in certain cases of hypertension, cardiovascular diseases and obesity.

Precaution and Warning – When to Avoid Glyciphage 500 MG Tablet?

Certain groups of people, like very young, sick, and pregnant women, are more susceptible to experience side effects of this medicine. When such people use Glyciphage, it should be used with extra care and caution.

A few other points that should be considered while consuming this medicine are:

  • Drug Allergy: If the patient is allergic to antidiabetic drugs or metformin, the use of this medicine should be avoided.
  • Impaired Kidney Function: If the patient has a known history of renal impairment, the use of this drug should be avoided. Consuming Glyciphage 500 MG Tablet in such cases may increase the risk of heart attack and septicemia. Appropriate dose adjustment and close monitoring of kidney function parameters should be taken into account in such cases.
  • Metabolic Acidosis : Use of this medicine in patients suffering from unbalanced acid levels in the body should be avoided.
  • Pediatrics: Use of Glyciphage in children below the age of 10 years is not recommended.

Substitutes of Glyciphage:

Various substitutes of Glyciphage 500 MG Tablet available in the market are:

  • Met Small 500 MG Table
  • Glup 500 MG Tablet
  • Insumet 500 MG Tablet
  • Forminal 500 MG Tablet
  • X Met 500 MG Tablet
  • D Met 500 MG
  • Eumet 500 MG
  • Exermet 500 MG
  • Gluformin 500 MG

Read More: Pantocid Substitutes | Enterogermina Substitutes

Glyciphage Interaction with Other Drugs:

Drug interactions

Taking Glyciphage in combination with other over the counter medicines, herbal medicines or vitamin supplements can increase the risk of side effects. Glyciphage 500 MG Tablet is known to interact with the following drugs or herbal supplements:

  • Estradiol: A patient should consult a doctor if he or she is planning to take Estradiol with Glyciphage. In this case, dose adjustments may be required. It is essential that one should tell their doctor about all other medicines they are taking. One should not stop the use of any medicine without consulting their doctor.
  • Aloe Vera: Patients should talk to their doctor before using aloe vera if they are diabetic. Depending on the dosage, the use of aloe vera may reduce blood glucose levels in some patients. This may demand a reduction in the dosage of this tablet. Hence, it is advised not to use any medicine without asking the doctor.
  • Amlodipine: Co-administration of Amlodipine with this medicine may reduce the effectiveness of it. Hence, patients should discuss the use of either medicine with the doctor.
  • Gatifloxacin: Co-administration of Gatifloxacin and Glyciphage is not advisable.
  • Iodinated Contrast Media: The intravascular administration of iodinated contrast media to patients who are taking this medicine can cause lactic acidosis. Therefore, it is advised to stop the usage of glyciphage 48 hours before taking Iodinated Contrast Media. Patients should inform the doctor about the usage of Glyciphage 500 MG Tablet so that relevant precautions can be taken.

Interaction with alcohol

Combining Glyciphage with alcohol may result in symptoms like prolonged weakness, muscle pain, and difficulty in breathing. It is advisable to avoid alcohol during the course of the treatment.

Disease Interaction

It should never be consumed if the patient is suffering from:

  • Vitamin B12 deficiency
  • Lactic Acidosis

Variants of Glyciphage:

Variants of Glyciphage 500 MG Tablet are:

  • Glyciphage 500 mg Tablet
  • Glyciphage 250 Tablet
  • Glyciphage 850 Tablet
  • Glyciphage SR 1gm Tablet
  • Glyciphage SR 500 mg tablet
  • Glyciphage SR 850 mg tablet

Medicines that should not be taken with Glyciphage:

Taking two or more medicines may change the effect of the medicine or may increase the risk of side-effects. Mentioned below are some of the medicines that may react with Glyciphage 500 MG Tablet, they are:

  • Aloe Vera
  • Estradiol
  • Amlodipine
  • Iodinated Contrast Media
  • Gatifloxacin
  • Amiloride
  • Clarithromycin
  • Digoxin
  • Olanzapine
  • Prednisone
  • Ranitidine
  • Sulfinpyrazone
  • Triamterene
  • Trimethoprim
  • Vancomycin

How to Store Glyciphage?

It is advisable to store the medicine in a cool and dry place, away from the reach of children and pets. The packaging of the medicine must be kept intact in order to maintain its effect when being administered.

Frequently Asked Questions

1) What should I do in case I miss a dose of Glyciphage?

Ans: In case of a missed dose of this tablet, it is recommended to take the missed dose as soon as it is remembered. However, it is not advisable to take the missed dose if it is almost the time for the next dose.

2) What should I do in case of an overdose of Glyciphage 500 MG Tablet?

Ans: Patients should reach out to the doctor immediately if an overdose is suspected. An overdose of this medicine may cause serious side effects such as nausea, low blood pressure and fatigue.

3) Can I drive or operate heavy machinery after taking Glyciphage?

Ans: Glyciphage 500 MG Tablet may cause sedative effects and therefore driving or operating any heavy machinery is not recommended after consuming this drug. If you experience any symptoms like blurred vision or dizziness, refrain yourself from using heavy machinery.

4) Is Glyciphage addictive?

Ans: No, Glyciphage 500 MG Tablet is not addictive. Addictive medicines are categorized under schedule X or schedule H in India and under I-IV in the US. Check the package or consult a doctor for more information on the same.

5) Is Glyciphage safe to use during pregnancy?

Ans: Yes, Glyciphage can be used by pregnant women. However, it should be used only if the potential benefits outweigh the risks. Consult your doctor if you are pregnant or planning to be.

6) Is Glyciphage a banned drug?

Ans: No, Glyciphage is not banned in India. You can even get it over the counter without any prescription yet, it is advisable to consult a doctor before consuming it.

7) Does the dosage of Glyciphage vary from patient to patient?

Ans: Yes, the dosage of Glyciphage 500 MG Tablet varies from patient to patient. The dosage that a doctor recommends depends on the following factors:

  • Age and BMI of the patient
  • The severity of the ailment
  • Other health concerns like Vitamin B12 deficiency and lactic acidosis etc.

8) What to do if an expired dosage of Glyciphage is consumed?

Ans: Taking a single dose of expired medicine will not cause any side effect. An expired medicine may not give you the desired results. However, if accidentally an expired dosage of Glyciphage 500 MG Tablet is consumed, contact your doctor immediately. It is advisable not to use expired medicine.

9) What is the recommended dosage of Glyciphage 500 MG tablets?

Ans: The minimum and maximum dosage of Glyciphage 500 MG Tablet varies from patient to patient. Usually, doctors prescribe 2 to 3 tablets a day to adults and 1 to 2 tablets a day to children belonging to the age group of 10 to 16 years.

10) Can I take Glyciphage with paracetamol?

Ans: Yes, you can consume paracetamol with Glyciphage; no interactions have been reported. However, you should discuss with your doctor the risks and benefits associated with the medicine.

11) Is it safe to consume alcohol with Glyciphage?

Ans: No, it is not safe to consume alcohol with this tablet. Taking Glyciphage with alcohol can cause lactic acidosis.

12) Can Glyciphage cause insomnia?

Ans: Yes, It may cause insomnia. On contrary, Glyciphage is proved to be effective in preventing sleep apnea. The exact relationship between this tablet and sleep apnea is not clear yet, further studies are required for a better understanding.

13) What are the side effects of Glyciphage 500?

Ans: Like any other medicine, Glyciphage 500 MG Tablet can also cause side effects ranging from mild to severe. These include:

  • Abdominal pain
  • Nausea
  • Diarrhea
  • Flatulence
  • Headache
  • Heartburn
  • Weakness
  • Change in taste
  • Respiratory tract infections
  • Allergic skin reactions
  • Muscle ache
  • Irregular heartbeat
  • Sweating
  • Confusion

If any of these side effects occur, immediately follow-up with your doctor.

14) Can Glyciphage cause sweating?

Ans: Yes, Glyciphage may cause night sweats in patients in a few cases.

15) Can Glyciphage cause weight loss?

Ans: Glyciphage is prescribed to people suffering from diabetes to treat their blood sugar levels. It helps in losing weight by suppressing appetite. It reduces insulin levels that helps in preventing the complications associated with diabetes. People who eat a healthy diet and exercise regularly while taking this medicine tend to lose more weight.

16) Can Glyciphage cause deficiency of vitamin B12 in patients?

Ans: Yes, using Glyciphage for a prolonged period may cause vitamin B12 deficiency in the body. This is because the long-term use of this medicine may affect  the absorption of vitamin B12 in the stomach.

17) What precautions should be taken while administering Glyciphage?

Ans: The following precautions must be taken while administering the medicine:

  • Avoid drinking alcohol as it may alter the effect of the medicine.
  • It is advised not to increase the dose of the medicine.
  • Caution must be taken by patients suffering from kidney or liver related ailments.
  • One should not alter/stop the use of this medicine unless recommended by the doctor. Abrupt discontinuation of the medicine may cause illness to return.

18) Do I need to avoid any particular food items while taking Glyciphage?

Ans: No, there are no food items or beverages that should be avoided while taking Glyciphage.

19) Is it safe to take Glyciphage if I have Polycystic Ovary Syndrome (PCOS)?

Ans: Yes. Glyciphage is safe for use by females suffering from PCOS. It is used for lowering the level of insulin and blood sugar in females suffering from PCOS. It helps in regulating the menstrual cycle, ovulation and reduces the risk of miscarriage. It also helps in reducing cholesterol and improves metabolism.

20) Does Glyciphage cause lactic acidosis?

Ans: Yes, the consumption of Glyciphage may cause lactic acidosis. The condition is characterized by an increased level of lactate in the body.

21) What factors are required to be monitored while taking Glyciphage?

Ans: Depending on the medical history the patient, the doctor may advise the patient to monitor the following conditions:

  • Patients suffering from kidney related ailments are advised to monitor their kidney function regularly.
  • Diabetic patients are advised to regularly monitor their blood sugar levels during the course of the medication to track improvement.

22) How does Glyciphage work?

Ans: Glyciphage works by controlling the production of hepatic glucose in the body. It also lowers the level of blood sugar by suppressing the amount of glucose being produced by the liver.

23) What are the medical conditions in which the use of Glyciphage is not recommended?

Ans: A person suffering from the following medical conditions is not recommended to administer Glyciphage:

  • Allergic Reactions- A patient with a known history of allergic reaction to any ingredient present in the medicine is not advised to administer Glyciphage 500 MG Tablet.
  • Metabolic Acidosis- Patients suffering from this condition are advised to avoid the use of this medicine as it may cause increase in the level of acid being secreted by the kidney.
  • Kidney disease: The medicine should be taken with care and caution by the patients suffering from kidney disorder as it may give rise to conditions such as heart attack, shock and Septicemia.
  • Type I diabetes - This medicine should not be taken by patients suffering from Type I diabetes since it is not effective in treating the symptoms associated with Type I Diabetes.

24) Can I take contraceptive pills while administering Glyciphage?

Ans: No. As the interaction between birth control pills and Glyciphage 500 MG Tablet is not known, their co-administration is not recommended. It is recommended to consult a doctor before taking any other medicine while administering it.

25) Can I stop taking Glyciphage if I see improvement in my symptoms?

Ans: No, it is not advised to alter or stop the dosage of the medicine unless advised by the doctor, even if you see an improvement in your symptoms.

26) Can I take Glyciphage while breastfeeding?

Ans: Women who are breastfeeding are generally not recommended to use Glyciphage 500 MG Tablet unless it is prescribed by the doctor. It is advised that women should discuss all the possible risks and benefits before taking this medicine.

Read More: Voveran | Rantac 150 MG Tablet | ime-9 | Patanjali Aloe Vera Gel

Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

Leave a Comment