Livogen Tablet: Uses, Side Effects, Composition, Price & Dosages

Livogen Tablet

Livogen Tablet is manufactured by Merck Ltd. Livogen is primarily used for the treatment of anemia and deficiency of folic acid. Livogen is also used as a supplemental medication for diseases which cause a deficiency of iron and folic acid in the body. The active ingredients found in Livogen include:

  • Elemental Iron (Ferrous Fumarate) – 152 mg
  • Folic Acid (Vitamin B9) – 1.5 mg

It works by acting on the bone marrow to produce a normoblastic marrow and promotes blood cell production in the body. Other conditions for which Livogen is prescribed as a supplementary medicine include low RBC or hemoglobin count, childhood anemia and megaloblastic anemia. The Livogen must be taken only after a doctor’s prescription. The doctor may prescribe different variants based on your health condition, age, and requirement.

The following variants of Livogen Tablet are available:

  • Livogen -Z Captab
  • Livogen-XT Tablet
  • Livogen Hemtonic Syrup
  • Livogen Injection

Uses and Benefits of Livogen:

Livogen Tablet is used for the treatment of symptoms and ailments arising out of or resulting in a deficiency of iron in the body. Patients suffering from anemia or any deficiency of iron (which is particularly common in women) may be prescribed Livogen. Patients of megaloblastic or nutritional anemia may equally be treated with Livogen. Livogen is also used to treat nutritional anemia caused by a poor diet, poor uptake of nutrition by the body, pregnancy, or other reasons. Folic acid deficiency may also cause anemia, which is treated by use of Livogen.

The following health conditions can be treated with Livogen Tablet:

  • Iron deficiency anemia
  • Deficiency of folic acid
  • Megaloblastic anaemia (deficiency of folic acid and vitamin B12)
  • Anaemia of nutritional origin
  • In cases of increased demands – lactation, infancy, childhood
  • Pregnancy
  • Malabsorption syndrome(poor absorption of food) – tropical sprue, celiac disease

Treatment of Anaemia with Livogen Tablet:

Anaemia is a condition developed as a result of a deficiency of haemoglobin (red blood cells) in the body. If the red blood cell count is low, the cells are unable to get enough oxygen which jeopardises the energy one feels throughout the day.

The following factors cause a lack of iron in the body:

  • Limited Nutrition – when the diet lacks nutrition, there is a chance of acquiring Anaemia.
  • Pregnancy – women need to produce more blood in order to ensure healthy baby growth. In case one suffers from low levels of dietary iron and vitamin B9, the doctor prescribes this supplementary medicine.
  • Childhood Anaemia – a chance of lack of nutrition among children is quite common for which iron supplements may be prescribed. In some cases, anaemia in children may be hereditary which may require special attention.
  • Megaloblastic Anaemia – Human bone marrow is a place of production of blood cells. Red blood cells (RBCs), white blood cells (WBCs) and platelets are all produced here. This health condition occurs when this process is disturbed and a large amount of RBCs or WBCs are produced. The large sized RBC cells are called Megaloblasts which are useless for the body and in fact block healthy oxygen supply. Lack of sufficient folic acid (vitamin B9) supply in the diet leads to this type of anaemia which may be prescribed in such conditions.

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Side Effects of Livogen:

Livogen is generally safe, but on prolonged or incorrect use may cause side-effects. Side-effects are usually not severe. If side-effects prolonged, then it is advisable to consult a medical professional immediately.

It is usually not advised that to discontinue the medication without medical intervention.

The following side effects are evident:

  • Nausea
  • Vomiting
  • Allergic reactions
  • Discomfort in stomach and intestine
  • Abdominal pain
  • Constipation
  • Darker coloured stool
  • Gastric irritation
  • Heartburn
  • Stomach ache
  • A sore throat and trouble in swallowing
  • Leg pain
  • Darkened skin or urine colour

Less serious side effects of Livogen tablet:

  • Confusion
  • Depression
  • Easily angered and annoyed
  • The feeling of throwing up
  • Gas
  • Itching
  • Loss of appetite
  • Not feeling well
  • Over-excitement
  • Rashes
  • Sleep disorder
  • Swelling of the abdomen
  • Taste problems

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Common Dosage of Livogen Tablet:

The dosage should be decided solely by a medical professional who is aware of the patient’s medical history. Livogen is a prescription-only medicine and must only be taken post consultation with a doctor. Patients are advised not to chew Livogen but to swallow it as a whole with water. The dosage of Livogen must not be extended or consumed in larger quantity than what the doctor has recommended.

Generally, it is recommended to be taken empty stomach, at least one hour before or two hours after a meal. Along with the dosage recommended for Livogen, it is extremely important to follow the diet plan recommended by the doctor to facilitate better absorption of the medicine. Consume enough iron-rich foods in order to get maximum iron from natural food sources.

Livogen Tablet Missed Dosage

In case a dose of Livogen is missed, it should be taken as soon as it is remembered. If the missed dose of Livogen is remembered when it is time for the next dose, then the missed dose should be skipped in order to take the next scheduled dose on time. One should ensure no extra doses are taken to make up for the missed dose.

Overdosage of Livogen Tablet

Taking more than the prescribed dosage of Livogen may cause harmful side effects. It is advised to consult the doctor in case of any such side effects. An overdose of Livogen can turn fatal, especially in the case of young children. Symptoms of an overdose of Livogen include:

  • Nausea
  • Severe stomach ache
  • Bloody diarrhea
  • Coughing up blood
  • Vomit looking like coffee grounds
  • Shallow breathing
  • Weak and rapid pulse
  • Pale skin
  • Blue lips
  • Seizures

It is good to monitor effects of Livogen by performing blood tests like complete blood count. It must be taken with food. Also, it is wise not to take milk, calcium, and antacids at the same time as that of Livogen.

Expired Dose

  • A single expired dose of Livogen may not cause any major side effects. Expired medicine, however, gets reduced in potency and hence may not work effectively on the other side.
  • Ensure to check the package of the medicine in order to confirm the date of expiry of Livogen.

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Composition & Nature of Livogen:

Livogen has two active ingredients which it uses to work on iron deficiency:

Folic Acid - Vitamin B9 - 1.5 MG

Ferrous Fumarate - 152 MG

The composition of Livogen mentioned above helps stimulate the synthesis and maintenance of nucleoprotein in erythropoiesis and is useful in treating the main health condition for which it is prescribed – anaemia.

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How Livogen works?

The mechanism of action of Livogen involves the following:

  • It normalises megaloblastic bone marrow to produce healthy RBC.
  • Helps in supplying sufficient elemental iron or ferrous fumarate, which is responsible for regulating oxygen supply through RBC to various parts of the body.
  • Livogen also performs immune enhancing, cognition enhancing and anticancer activities.
  • Livogen is made up of ferrous fumarate which gets absorbed in the body by the duodenum and jejunum with the help of gastric acid. It is then supplied through the gastrointestinal mucosa and binds with haemoglobin.
  • Livogen also consists of Folic acid, which is nothing but vitamin B9. It is used as a supplement and in the treatment of diseases caused by Folate deficiency.
  • Folic acid is absorbed by the small intestine and then it binds with plasma proteins.
  • Folic acid plays a major role in the absorption of iron in the body.
  • Livogen tablets act on the megaloblastic bone marrow which promotes a normoblastic marrow in the patient. It then leads to the production of blood cells and platelets which support the patient to reduce anaemia.
  • Folic acid or vitamin B9 is required for producing DNA, RNA and vitamin B12. It hence forms of the system producing new red blood cells in the human body.

Warnings/Precautions- When to avoid Livogen Tablet?

  • Not all anemia can be treated solely by Livogen. Pernicious anemia and some megaloblastic anemia disorders are caused by Vitamin B12 deficiency. The medicine administration will not treat the symptoms of these disorders and overconsumption of folic acid may harm the patient. Moreover, folic acid consumption over 0.1 mg per day may complicate the diagnosis of pernicious anemia.
  • Patients with pre-existing high levels of iron should not be using Livogen.
  • Patients who have an allergy or intolerance to the components of the medicine should inform their doctor. If the patient is not aware of intolerance but faces complications like swelling in face, neck, tongue, or difficulty breathing, then they should ask for emergency medical treatment as anaphylactic reactions may be fatal.
  • Children less than four months old should not be administered the medicine.
  • Patients with a number of diseases, such as kidney infections, porphyria, bowel problems, Crohn disease, Colitis, Diverticulitis, should inform their doctor before taking the Tablet.
  • Patients who are planning to become pregnant or are breastfeeding are generally advised against using the medicine, unless absolutely necessary.
  • Patients using the tablet should avoid alcohol consumption, particularly patients having alcoholic cirrhosis of the liver.
  • People with an active peptic ulcer or intestinal ulcer problem must not take the Tablet.
  • It must be avoided strictly by people with a history of repeated blood transfusions.
  • Prolonged use of medicine must be avoided.
  • People with a problem of haemoglobin in the blood should avoid the drug.
  • In case one is suffering from Folic acid-dependent tumors, It is not recommended for them.

Substitutes for Livogen:

Some drugs have the same ingredients and composition as Livogen Tablet and hence can be taken as a substitute. They are:

  • Fe3 XT Tablet (10 Tab) – manufactured by Dr. John’s Lab Pharma Pvt. Ltd.
  • Ferikind Tablet (10 Tab) – manufactured by Lifestar Pharma Pvt. Ltd.
  • Hemfer XT Tablet (10 Tab) – manufactured by Alkem Laboratories
  • Richar XT Tablet (10 Tab) – manufactured by Alembic Pharmaceuticals Ltd.
  • Zebita XT Tablet (10 Tab) – manufactured by Ind Chemie

Livogen Tablet Variants:

The Livogen is available in the following variants which act as substitutes to each other in treating regular pain conditions.

  • Livogen Captab - Ferrous Fumarate (Iron) and Folic Acid (vitamin B9)
  • Livogen-Z Captab - Ferrous Fumarate (Iron), Folic Acid (vitamin B9), Zinc Sulphate
  • Livogen-XT Tablet - Ferrous Ascorbate (Iron), Folic Acid (vitamin B9), Zinc Sulphate
  • Iron, Folic Acid (vitamin B9) - Iron, Folic Acid (vitamin B9)
  • Livogen 5ml Injection - Iron (100mg)

Livogen Interactions:

It is known to react with several medications. Using the medications listed here alongside Livogen may increase the risk of side effects or reduce the efficacy of either or both the medicines. Patients should always inform their physician of any medication they are taking while getting a consultation. It may react badly with all barbiturates, cholecalciferol, ascorbic acid, Diphenylhydantoin, acetaminophen, levothyroxine, albuterol, methotrexate, montelukast. It may also interact with alcohol and patients are advised not to take it while using the medicine. Even herbal supplements or Ayurveda medicines may interact negatively with medicine. It is best to inform your doctor of all extraneous supplements the patient may be ingesting.

Commonly Asked Questions:

1) How long do I have to use Livogen to cure iron deficiency?

Ans: It should be used as per your doctor’s orders. The length of time it takes to cure iron deficiency is dependent on the cause. There are genetic illnesses that may be causing iron deficiency in which case Livogen may not be useful. For patients who have a folic acid deficiency and a mild or moderate case of iron deficiency, it may take only a few weeks or months to cure their iron deficiency.

2) How does Livogen Tablet contribute to healthy hair growth?

Ans: Although a healthy and nutritious diet is the primary necessity for promoting healthy hair growth along with proper external care, iron levels also determine hair growth to a great extent. This mineral plays a major role in transporting oxygen throughout the body along with promoting healthy hair, nail and skin growth.

Women are particularly affected by iron deficiency especially due to their monthly cycles. Iron supplements like Livogen also help in boosting oxygen supply to the scalp, strengthening of hair roots, promoting healthy hair follicles, preventing dandruff, supporting the growth of thick and glossy hair, besides other benefits.

3) How should Livogen be stored?

Ans: The following instructions for storage of Livogen must be followed:

  • It must be stored at room temperature away from direct sunlight and heat.
  • Keep the Tablet away from children and pets.
  • The ideal temperature for storing the Tablet is below 25 degrees Celsius.
  • A locked cupboard at least one-and-a-half meters above the ground is a good place to store medicines.
  • Do not use the medicine after the expiry date given on the label.
  • The expiry date refers to the last day of that month.
  • It should not be disposed of via wastewater or household waste.
  • Ask your pharmacist on how to dispose of medicines no longer required. These measures will help protect the environment.

4) Can I take iron and calcium supplements together?

Ans: No, iron and calcium supplements must never be taken together. One can take calcium supplements with meals and iron supplements are to be taken on an empty stomach only. This ensures that iron is properly absorbed by the body. There should be a gap of at least five hours between iron and calcium supplements. Inform the doctor about any ongoing calcium supplement so that they can accordingly plan the dose for an iron supplement.

5) What are some useful tips for using Livogen Tablet?

Ans: The following useful and smart tips can be helpful for understanding the use of Livogen.

  • Tea, coffee, calcium, eggs, zinc, antacids, etc. reduce proper absorption of iron hence one must avoid taking these along with oral iron supplements.
  • Do not stop treatment with the Tablet on your own even if symptoms of anaemia disappear. Stop it only if your doctor has advised. A dose for more than six months is not recommended.

Livogen works effectively when taken as per doctor’s prescription. Ensure to notice any possible side effects and discuss with the doctor in case the side effects do not go away after the initial few weeks.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

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