Lopamide 2 MG Tablet: Uses, Side Effects, Composition, Dosages & Price

Manufactured by Torrent Pharmaceuticals Ltd, Lopamide is an antidiarrheal drug that is used to treat non-infective diarrhoea, loose stools, mild travellers’ and idiopathic diarrhoea. It cures sudden diarrhoea by reducing the bowel movement and making stool less watery.

Nature Antidiarrheal
Uses Acute and chronic diarrhoea, Ileostomy, Travelers’ Diarrhea
Composition Loperamide
Side effects Constipation, Bloating, Loss of appetite, Dry mouth, Stomach ache. Paralysis Ileus
Precautions Hypersensitivity, Abdominal Pain, Acute Colitis, Antibiotic-Induced Diarrhea Pregnancy, breastfeeding

Lopamide 2 MG Tablet

Lopamide contains Loperamide that works by acting on the opioid receptor in the wall of the food pipe to reduce rhythmic contraction. This helps food to stay longer in the intestines, thereby absorbing more water and electrolyte from the food. This, in turn, makes the stool more solid to relieve the symptoms of diarrhoea.

Uses and Benefits of Lopamide:

Lopamide is categorized as an antidiarrheal medicine that is used for treating the following conditions:

  • Acute and chronic diarrhoea : Lopamide is used for treating diarrhoea that lasts for a longer duration. It works by slowing down the movement of the gut. This medicine treats only the symptoms, not the cause of this infection. It also helps relieves symptoms of Irritable Bowel Syndrome (IBS).
  • Ileostomy: Ileostomy is a surgical procedure that involves removal of the damaged part from the ileum and diverting the cut end to an artificial opening in the abdominal wall. This medicine helps reduce the amount of stool produced in patients who have undergone such surgical process.
  • Travellers’ Diarrhea : Lopamide is used for treating the symptoms of diarrhoea associated with an infected gut. It mostly affects people who travel for a long duration of time.
  • Bowel movement : Lopamide helps minimize the movement of the gut. This reduces the bowel movement by making the stool less watery.

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Side effects of Lopamide:

Lopamide is a safe medicine that shows no major side effect when consumed in accordance with the prescription of the doctor. However, in certain cases, it may show some side-effects. A few common side-effects of Lopamide are:

  • Constipation
  • Bloating
  • Loss of appetite
  • Severe abdominal pain
  • Dry mouth
  • Dizziness
  • Allergic reactions on the skin
  • Paralytic ileus
  • Cephalalgia
  • Flatulence
  • Headache
  • Nausea
  • Indigestion

If a patient experiences any of the above-mentioned side effects, he or she must contact a doctor at the earliest.

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Common Dosage of Lopamide:

The maximum permissible dosage of Lopamide for adults is 16 mg or 8 tablets over a period of 24 hours. However, the age of an individual, the severity of the diarrheal conditions and other underlying health conditions may alter this limit.

  • Missed Dose: Patients should take the missed dose as soon as it is remembered. However, it is advisable not to take the missed dose if it is almost time for the next dose.
  • Overdose: Overdosage may show serious side effects or drug toxicity and thus one should refrain from taking an overdose. However, if an overdose is suspected, one must rush to a doctor to seek immediate medical attention

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Composition and Nature of Lopamide:

Lopamide 2 MG Tablet is an antidiarrheal medicine that is used for treating diarrhoea by slowing down the movement of the gut. The active ingredient of this medicine is Loperamide. It is manufactured by Torrent Pharmaceuticals Ltd and comes in the form of a tablet.

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Lopamide 2 MG Tablet Price in India:

Variant Price (INR) Quantity
Lopamide 19.93 10 Tablets

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How Lopamide works?

Loperamide is an antidiarrheal drug that works by acting on the opioid receptor in the wall of the food pipe to reduce rhythmic contraction. This helps food to stay longer in the intestines, thereby absorbing more water and electrolyte from the food. This, in turn, makes the stool more solid to relieve the symptoms of diarrhoea. This medicine also works by increasing the tone of anal opening and thus reducing the sense of urgency associated with diarrhoea.

How to use Lopamide?

The medicine should be consumed as per the prescription of the doctor or the patient should follow the directions prescribed on the label. One must not increase or decrease the dosage without consulting the doctor. It is advised to swallow the tablet as a whole, without chewing, crushing or breaking it. Absorption of Lopmaide is not affected by food and thus can be taken with or without food, as instructed by the doctor.

When is Lopamide Prescribed

Lopamide is primarily used to treat and relieve the symptoms associated with Travelers’ Diarrhea, Acute, and chronic diarrhoea and Ileostomy. Doctors may also prescribe this medicine to treat non-infective diarrhoea and loose stools. In certain cases, it may also be prescribed to treat idiopathic diarrhoea in patients suffering from AIDS.

Precaution and Warning – When to Avoid Lopamide?

Lopamide is an antidiarrheal drug that may cause extreme dizziness and drowsiness affecting one’s physical activities. Also, it is advised to quit alcohol during the dosage period as it multiplies the risk of side-effects. Other concerns that should be taken into consideration before consuming this medicine include:

  • Hypersensitivity : Lopamide is not recommended for patients with any kind of allergy to antidiarrheal drugs. In such cases, the drug may show severe allergic conditions. Steven’s Johnson is the most common allergic reaction caused to people who have hypersensitivity to this drug.
  • Liver Disease : Lopamide shows severe side effects in patients with an impaired liver. It should be used with extra care and caution in patients having a known history of any liver-related disorder. Appropriate adjustment to the dose and close monitoring of liver function are required in such cases.
  • Pregnancy : Use of this medicine in pregnant women should be avoided unless potential benefits outweigh the risks.
  • Breastfeeding : This medicine should be avoided by the ladies during their lactation period as it may mix with the blood and may affect the quality of breastmilk.
  • Infectious Diarrhoea : This medicine should not be used in case of infectious diarrhoea that is accompanied with blood and pus in stools. Lopamide may show adverse effects in such cases.
  • AIDS : This medicine should be avoided by the patients suffering from AIDS as their antiviral medicines may react adversely with Lopamide.
  • Heart Diseases : Lopamide shows adverse effects on the heart and blood vessels and thus should be avoided by those who are suffering from heart diseases.
  • Paediatrics : Use of this medicine in children below 2 years of age is not advisable. For children above two years, it should be used with extreme care and caution. Consult a doctor before giving this medicine to children.

Substitutes of Lopamide:

Following is the list of medicines that have the same composition as that of Lopamide and thus can be used as its substitute:

  • Imodium 2mg Tablet manufactured by Janssen Pharmaceuticals.
  • Loperamide 2mg Tablet manufactured by Cadila Pharmaceuticals Ltd.
  • Lomid 2mg Tablet manufactured by Agron Remedies Pvt Ltd.
  • Rokamide 2mg Tablet manufactured by Sun Pharmaceuticals Industries Ltd.
  • Tropamide 2mg Tablet manufactured by Troikaa Pharmaceuticals Ltd.
  • Sestil AD Tablet manufactured by Vanguard Ltd.
  • Lomofen Plus Tablet manufactured by RPG Life Sciences Ltd.
  • Andial 2mg Tablet manufactured by Veritaz Healthcare Ltd
  • Loperamide 2mg Tablet manufactured by Cadila Pharmaceuticals Ltd
  • Lopox 2mg Tablet manufactured by Shalman Pharma Pvt Ltd
  • Loparet 2mg Tablet manufactured by Retort Pharma Pvt Ltd
  • Lopamax 2mg Tablet manufactured by Wockhardt Ltd
  • Lopide Tablet manufactured by Makers Laboratories Ltd
  • Lopramac 2mg Tablet manufactured by Mac Millon Pharmaceuticals Pvt Ltd
  • Lupidium Tablet manufactured by Lupin Ltd
  • Diarsec 2mg Tablet manufactured by Biochem Pharmaceutical Industries
  • Loramyl 2mg Tablet manufactured by Adonis Laboratories Pvt Ltd
  • Rokamide 2mg Tablet manufactured by Sun Pharmaceutical Industries Ltd
  • Eldoper 2mg Tablet manufactured by Micro Labs Ltd

Lopamide Interaction with Other Drugs:

Drug Interactions:

Drug interactions may change the workings of any prior medication and can also increase the risk of any serious side effects. It is best not to start, stop or change the dosage of any medication unless the patient has got approval from the doctor.
Avoid taking this medicine if an individual is on following drugs:

  • Clarithromycin
  • Quinidine
  • Ketoconazole
  • Ranitidine
  • Ritonavir

Interaction with alcohol:

Lopamide should never be combined with alcohol as it has a tendency to cause extreme drowsiness and dizziness when mixed with alcohol.

Disease Interaction:

Lopamide should never be consumed in case of:

  • Infectious Diarrhoea
  • Cardiac Diseases
  • Liver Impairment

Medicines that should not be taken with Lopamide:

Mixing two or more medicines may change how the drug works and may increase the risk of side-effects. A few drugs that should not be taken with Lopamide are:

  • Clarithromycin
  • Ritonavir
  • Quinidine
  • Ranitidine
  • Ketoconazole

How to Store Lopamide?

It is advisable to store the medicine in a cool and dry place away from direct heat and sunlight. One must keep the medicine away from the reach of children and pets. The packaging of this medicine must be kept intact in order to maintain its effect when being administered.

Frequently asked questions

1) Does Lopamide 2 MG Tablet show any addictive tendency?

Ans: No. Lopmaide does not possess an addictive tendency. However, it is advised to consult a doctor to know more about the nature of this medicine.

2) Can I stop the consumption of Lopmaide Tablet immediately or do I have to gradually stop using it?

Ans: Consumption of Lopmaide can be stopped immediately. However, it is better to consult a doctor before discontinuing the drug.

3) Can I consume alcohol during the course of treatment?

Ans: No, consuming alcohol during the course of the treatment may increase the risk of sedative effects. Also, combining alcohol and Lopamide may show adverse effects on the liver.

4) Is Lopamide a narcotic substance or a steroid?

Ans: Lopamide is neither a narcotic substance nor a steroid. It is an antidiarrheal drug that works by slowing down the gut movement to relieve the symptoms of diarrhoea.

5) Can I operate heavy machinery after taking Lopamide?

Ans: It is better to avoid operating heavy machinery after taking Lopamide as the drug has the tendency to show side-effects such as a headache, drowsiness, hypotension, and dizziness.

6) Is Lopamide safe for infants?

Ans: No, use of this medicine in children below 2 years of age is not recommended. For children above two years, it should be used with extreme care and caution. Consult a doctor before administering this to children.

7) What are the storage requirements of Lopamide 2 MG Tablet?

Ans: Lopamide should be stored in cool and dry place, away from moisture and direct sunlight. It should be kept away from children and pets.

8) What are the important things to keep in mind while using Lopamide Tablet?

Ans: Lopamide is an antidiarrheal medicine that may cause extreme dizziness and drowsiness, which may affect one’s physical activities. Hence, it is advised to avoid driving and operating heavy machinery after administering this drug. This drug should not be used in case of liver impairment, pregnancy, lactation, AIDS, bloody stools and cardiac diseases. The use of this medicine should also be avoided by patients with a known allergy to Lopamide.

9) Can I discontinue the use of Lopamide without seeking the doctor’s advice?

Ans: No, you should not discontinue the use of Lopamide without consulting a doctor.

10) What are the side effects of administering Lopamide?

Ans: This prescription-only medicine must be taken only after consulting a doctor in order to avoid the occurrence of any side- effects. A few common side effects that may appear while consuming Lopamide are:

  • Bloating
  • Constipation
  • Decreased appetite
  • Severe stomach ache
  • Paralytic ileus
  • Allergic skin reaction
  • Dizziness
  • Dryness in mouth
  • Rashes
  • Itching
  • Nausea
  • Shortness of breath

If any of these side effects occur, then immediately contact your doctor.

11) Can Lopamide cause constipation?

Ans: Yes, Lopamide can cause constipation.  In case the patient experiences symptoms associated with constipation, he or she should stop consuming the medicine and must consult the doctor at the earliest.

12) Can Lopamide cause weight loss?

Ans: Yes, Lopamide can cause weight loss in some cases. Weight loss may occur due to reduced food intake caused by decreased appetite. If you experience a massive weight loss after taking this medicine, then immediately seek medical help.

13) Can I take warfarin along with Lopamide?

Ans: Yes, you can take warfarin with Lopamide. No drug-drug interaction has been reported in case of this combination. But, if you feel uneasiness after taking this medicine, then inform your doctor on priority.

14) What all medicines can be taken simultaneously with Lopamide 2 MG Tablet?

Ans: Lopamide can be taken with antibiotics, ibuprofen, and paracetamol. To be on a safer side, it is advised to consult a doctor before taking any of these medicines.

15) Can Lopamide provide relief in diarrhea?

Ans: Yes, Lopamide provides relief in diarrhoea. It works by decreasing the movement of the gut. It decreases the bowel movement and makes the stool less watery.

16) How much time does Lopamide take to show the desired results?

Ans: Lopamide shows its effect within 1-3 hours of administration. Usually, its effect lasts for an average duration of 40 hours.

17) Is Lopamide safe for lactating mothers?

Ans: No, use of Lopamide is not recommended for lactating mothers. However, for case-specific recommendations, one should consult a doctor.

18) Should I take Lopamide Tablet before a meal or after a meal?

Ans: Absorption of Lopamide is not influenced by food and thus, it can be taken before or after a meal. One must consult a doctor to know more about the dosage of Lopamide.

19) Can Lopamide be used to treat stomach cramps?

Ans: No, Lopamide does not cure stomach cramps. It is used only to treat acute diarrhoea.

20) Can I take Lopamide with paracetamol?

Ans: Yes, it is absolutely safe to take Lopamide with paracetamol. No drug-interaction has been reported for this combination. However, it is advised to consult a doctor before co-administering paracetamol and Lopamide.

21) What will happen if I accidentally take an expired dose of Lopamide?

Ans: One should abstain from taking an expired dose of Lopamide. However, if consumed accidentally, one should discuss the possibility of consequence and corrective measure with a doctor.

22) Under what medical conditions Lopamide should not be administered?

Ans: Lopamide should not be administered in the following medical conditions:

  • Allergy: You should not take this medicine if you are allergic to Lopamide or its active ingredient Loperamide.
  • Abdominal pain: Lopamide is not recommended for use if you are experiencing stomach pain without loose stools.
  • Acute colitis: Lopamide should not be used by patients suffering from an infected colon or diarrhoea. The symptoms of this condition may include high fever and blood in stools.
  • Antibiotic-induced diarrhoea: Do not take this medicine if you are suffering from diarrhoea caused by an antibiotic.

23) Can Lopamide cause low blood pressure?

Ans: No, Lopamide has not been reported for lowering the blood pressure. However, it may lower the blood pressure, if the medicine is consumed in more than the recommended quantity. Consult a doctor if you experience symptoms associated with low blood pressure such as blurred visions, lightheadedness and dizziness.

24) How does Lopamide work?

Ans: Lopamide works by slowing down the bowel movement in the intestine, thereby allowing more time for food to absorb. This helps in more absorption of salts and electrolytes to make stool less watery.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

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