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Magnex Forte Injection: Uses, Side Effects, Composition & Dosages

Magnex Forte is known to be a cephalosporin antibiotic. The medicine is available as an injection which has a combination of two drugs Cefoperazone and Sublactum. It is widely brought into use for the treatment of chronic bacterial infections in the human body.

One of the pharmacological features of Magnex Forte is that unlike the majority of cephalosporin antibiotics, Pseudomonas microbe caused infections are treatable efficiently with the combination of the two drugs Cefoperazone and Sublactum.

Magnex Forte is manufactured in India by the renowned medicine manufacturer, Pfizer Ltd.


Composition and Nature of Magnex Forte Injection:

The administration of the injection is a combination of two drugs namely the Cephiperazone and Sublactum. It is a bactericidal drug that completely eliminates the infection by stifling the growth of the bacteria while killing off the existing colonies that have come into existence within the human body.


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Uses and Benifits Magnex Forte Injection:

Magnex Forte is an antibacterial medication that is widely used today to treat bacterial infections and pathologies which can be brought about by several different strains of bacteria that could be found within the human body. These include:

  • Urinary tract infection
  • Skin and soft tissue infection
  • Surgical infections
  • Infections of the respiratory tract
  • Intra-abdominal Infections
  • Endometritis
  • Pelvic inflammatory disease
  • Gynecological infections
  • Bronchial infections
  • Peritonitis
  • Septicemia


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Side Effects of Magnex Forte Injection :

The common side effects of Magnex Forte might include Diarrhoea, altered liver function test (LFT), allergic reaction, and Anaemia

In certain cases Hypoprothrombinemia (blood-clotting disorder, spontaneous bleeding) have been known to be manifested. Other notable side effects could include --

  • Diarrhea
  • Pain at the site of injection
  • Allergic reactions
  • Rash
  • Neutropenia
  • Nausea
  • Vomiting
  • Inflammation of a vein caused by the blood clots

Magnex Forte Injection may also cause certain side-effects that are not listed here


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Dosage of Magnex Forte Injection:

Magnex Forte injection needs to be administered once, twice or even thrice a day depending upon the type and severity of infection that is being experienced by the patient. The dosage must be increased or decreased as per the advice of your physician. An over dose of this injection could lead to more harm than good. So care must be taken during its administration and it must be done only under medical supervision and guidance.


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How Magnex Forte Injection works?

This medicine is a Cefoperazone and is an antibiotic. It functions effectively by averting the development of the protective bacterial covering which is vital for the existence of bacteria in the human body. Sulbactam is a beta-lactamase inhibitor that decreases the resistance and improves the action of Cefoperazone against bacteria that could have developed.


As a combination of two medicines Cefoperazone and Sulbactam, Magnex forte shows the composite effect of the two drugs that are used as a blend with one another. Cefoperazone acts as a bactericidal by hampering the synthesis of the bacterial cell wall, and Sulbactam complements the bactericidal effect by inhibiting certain enzymes produced by the microbes which elevates the antibacterial activity of cefoperazone within the human body. The co-relation between the two drugs is what efficiently eradicates the bacterial infection from the patients body.


Warnings and Precautions Related to Magnex Forte Injection:

Known or foreseen hypersensitivity to Cefoperazone Sulbactam Injection must be seen as a contraindication. Cefoperazone Sulbactam Injection should not be used in the following conditions:

  • Asthma
  • Clostridium difficile infection
  • Diabetes
  • Hypersensitivity to antibiotics or cephalosporins
  • Kidney or gastrointestinal disease
  • Pseudomembranous colitis
  • gastrointestinal disease
  • Renal complications
  • Hepatic condition

In the course of the therapy, bloody or watery diarrhea must be treated as a serious sign and the physician must be contacted immediately. Whatever the symptoms that are being faced by the patient must be reported to the doctor so that he will be able to take prompt action on it before it gets too out of hand for cure. Completing the entire course of the antibiotic is imperative for the patient. It would be advisable to get a regularly check up of the urine function test for sugar levels that fluctuate within the patients body.


Substitutes for Magnex Forte Injection:

The following are common substitutes for Magnex Forte

  • Zostum, Zuventus Healthcare Ltd
  • Troyperazone, Troikaa Pharmaceuticals Ltd
  • Lactagard, Ipca Laboratories Ltd
  • Zonamax ES, Macleods Pharmaceuticals Pvt Ltd
  • Fytobact, Cadila Pharmaceuticals Ltd
  • Viatran, Cipla Ltd
  • Lactagard 1000mg/500mg Injection, Ipca Laboratories Ltd
  • Zosul Injection, Cipla Ltd
  • Omnibact Forte Injection, Aristo Pharmaceuticals Pvt Ltd


Magnex Forte Injection Interactions:

Usage of other drugs concurrently with Magnex forte might have an effect on its pharmacological activity. Elevation of the risk for side-effects or diluted effect of the drug can occur besides other dangerous reactions. The doctor must be aware about all the drugs, vitamins, and herbal supplements that are being used at the time by the patient.

Notably, Injection Magnex forte might have severe interactions with certain drugs and substances that include:

  • Alcohol
  • Amikacin
  • Allopurinol
  • Tobramycin
  • Aminoglycoside antibiotics
  • Probenecid
  • Gentamicin
  • Tetracyclines




1) Is Magnex forte safe for women who are pregnant and breastfeeding?

Ans: The combination of Cefoperazone and sublactum has not indicated any major risk factor for the developing foetus or the pregnant woman. Yet, to be on the safer side, the physician must take the call after taking into consideration the medical history of the patient. As in the case of lactating mothers, the drug is not known to pass on to the breast milk to cause toxicity to the baby who is being fed.


2) Can this medicine be used for the flu or common cold symptoms?

Ans: This drug is not meant to treat viral infections thus it is not indicated for the treatment of common cold.


3) Can you use heavy machinery or drive a vehicle when you are on this medication?

Ans: It is best for the ones on Magnex forte to not operate heavy machinery or drive heavy vehicles, etc. Although it is not specifically contraindicated it may cause dizziness and nausea in the person who has been advised its use.


4) Is this medicine addictive or habit forming in nature?

Ans: No, Magnex forte is an antibiotic and does not generate dependence of any kind. The withdrawal of the medication must be regimented by the physician nevertheless. 


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Last updated on : 17-01-2019

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