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Meprate Tablet: Uses, Dosage, Side Effects & Compositions

Meprate Tablet
Meprate  Tablet

Meprate Tablet is a progestin which helps regulate ovulation and menstrual cycles in females. The functioning of the drug is similar to that of a hormone called progesterone. Generally, Meprate is prescribed for the regularizing irregular periods, abnormal uterine bleeding, and amenorrhea.

Nature: Contraceptive
Composition: Medroxyprogesterone acetate
Uses:

Heavy bleeding during periods (Menorrhagia), Birth Control,

Heavy bleeding unrelated to periods, Delaying Periods,

Contraceptive, Renal Cell Carcinoma, Amenorrhea, Menstrual Cramps,

and Abnormal tissue growth in Uterus.

Side effects:

No Periods, Edema, Heavy bleeding once you stop Meprate,

Stomach Bloating, Anxiety & Depression, Weight Changes,

Nausea & Headache, Tender Breasts, Tiredness, Irritability,

Muscle Pain,  Fever, Pain or swelling in legs or hands,

Weakness, Jaundice Chest pain, cough, Breast lump, rapid breathing,

In the case of Menopause, it may also lead to vaginal bleedings,

Severe pelvic pain, Lupus, Asthma, and Epilepsy and more.

Precautions: Pregnancy, Breastfeeding, Alcoholism, Bone mineral density and more.

Meprate tablet can also help in stopping the overgrowth of the uterus lining. It can be used in hormone replacement therapy for treating various symptoms associated with menopause. Meprate also prevents the growth of endometrial hyperplasia and reduces the risk of developing uterine cancer.

Uses and Benefits of Meprate:

The most common use of Meprate is as a contraceptive. However, there are various other functions of the tablet:

  • Heavy bleeding during periods (Menorrhagia)
  • Birth Control
  • Menstrual Cramps
  • Heavy bleeding unrelated to periods
  • Delaying Periods
  • Contraception
  • Renal Cell Carcinoma
  • Amenorrhea
  • Endometrial Cancer
  • Endometriosis

Read More: I Pill  Uses | Ime-9 Uses

Side Effects of Meprate:

Medicines are known to cause some side effects after consumption and Meprate is no exception. The tablet might result in the below mentioned side effects.

  • Minor spotting or bleeding from the vagina
  • Irregular periods
  • Absence of menstrual bleeding
  • Pain in breasts
  • Heavy bleeding
  • Nervousness
  • Sleeplessness
  • Weakness, drowsiness, dizziness
  • Nausea
  • Loss of hair or abnormal growth of hair
  • Fever
  • Swelling
  • Vomiting Abnormal secretions from the vagina
  • Abdominal cramps and bloating
  • Depression
  • Weight gain
  • Thrombophlebitis (inflamed veins)
  • Blood clot

It is advised that the patients must inform the doctor in case of any adverse reaction to Meprate. This is a non-exhaustive list of the possible side-effects caused by Meprate tablet.

Apart from the above mentioned side effects, the consumption of the drug may also result in following side effects:

  • Insomnia
  • Acne
  • Change in appetite or weight loss
  • Breast discharge and tenderness
  • Loss of scalp hair
  • Itching
  • Rashes
  • Blurred Vision

Read More: Nicip plus Side Effects | Dolo 650 MG Side Effects

Common Dosage for Meprate:

One should take Meprate as prescribed by the physician. Do not self-medicate. One should not crush, chew or the bite this Tablet while consuming. It is advised to take the medicine at a fixed time and as per the dose prescribed by the doctor. The dosage of Meprate is based on the condition of the patient and how the patient’s body response to the treatment. The medicine may be taken before or after having a meal.

Itis the most effective when the course is started as soon as possible after spotting the symptoms associated with the condition.

  • Missed Dose: In case of missed dose, the patients should take the missed dose as soon as they remember about it. However, if it is time to take the next scheduled dose, then it is advised to skip the missed dose of the medicine and continue with the usual schedule.
  • Overdose: In case of overdose it is advisable to consult a doctor immediately.

Read More: Liv 52 Dosage | Methylcobalamin Dosage

Composition and Nature of Meprate:

Meprate constitutes of Medroxyprogesterone Acetate as an active ingredient. The Tablet works by replacing the natural progesterone in the body. This drug is very useful in regularizing irregular periods, providing relief from painful periods or treating absence of menstrual periods. This drug also prevents overgrowth of the womb lining in women who have hit menopause and are on the course of estrogen.

Price Table

Quantity of medicine Price (INR)
10 Tablets in 1 strip 56.5

Read More: Crocin Price | C Tax O Price

How Does Meprate works?

It contain Medroxyprogesterone, which is a synthetic derivative of female hormone progesterone, which implies that the chemical structure of the drug very closely resembles that of the naturally produced progesterone.

Progesterone is naturally produced by the ovaries during the second phase of the menstrual cycle. It performs on the endometrium or the lining of the uterus, changing the proliferating stage to the secretory stage. This causes the endometrium, which had thickened as a response to estrogen during the first half of the cycle, to stop growing and start secreting hormones and other proteins needed to maintain a pregnancy, if conception occurs; if not, levels of estrogen and progesterone fall and the endometrium is shed (menstruation).

How to Use Meprate Tablet?

It is Suggested to take Meprate tablet at a fixed time and as per the dose prescribed by the doctor. The tablet works best if taken before or after having a meal.

When Meprate is prescribed?

It is prescribed to prevent and treat a condition such as:

  • Menstrual Cramps
  • Amenorrhea
  • Endometrial Cancer
  • Endometriosis
  • Heavy bleeding unrelated to periods
  • Delaying Periods
  • Contraceptive
  • Heavy bleeding during periods (Menorrhagia)
  • Birth Control
  • Renal Cell Carcinoma

Warnings and Precautions Related to Meprate:

  • Meprate 10 mg Tablet is not safe to be used during pregnancy. Various human and animal studies have proved to have adverse effects on the fetus. It is advised that the patient consults a doctor before starting the course of the medicine.
  • Meprate can pass into body fluids. Patients are advised to wear rubber gloves when cleaning up the various bodily fluids and handling contaminated trash. One should wash hands before and after removing gloves.

Substitutes for Meprate:

Below is the list of medicines, which have the same composition, strength, and form as Meprate tablet and hence can be used as its substitute.

  • Medrogest 10mg Tablet manufactured by the Maneesh Pharmaceuticals Ltd
  • Medolin 10mg Tablet manufactured by the Lincoln Pharmaceuticals Ltd
  • Deviry 10Mg Tablet manufactured by the Torrent Pharmaceuticals Ltd
  • Dub 10Mg Tablet manufactured by the Unicure India Pvt Ltd
  • Medona 10Mg Tablet manufactured by the West-Coast Pharmaceutical Works Ltd
  • Empeea 10Mg Tablet manufactured by the Pfizer Ltd
  • Regeeva 10Mg Tablet manufactured by the Novartis India Ltd
  • Provera 10mg Tablet manufactured by the Pfizer Ltd

Read More: Mulethi Substitutes | Myoril Substitutes

Interactions with Meprate Tablet:

Interaction with Alcohol:

Consuming this medicine with alcohol may result in drowsiness or dizziness. It is prescribed not to take the medicine with alcohol to avoid any side effect.

Interaction with Diseases:

The active ingredient Medroxyprogesterone Acetate present in the Meprate tablet may cause severe interactions if taken by patients suffering from certain medical conditions. It is advisable to consult a doctor before administering the medicine if the patient is suffering from the conditions listed below:

  • Depression : It should be used with caution in patients with a history of depression. Consumption of this tablet may make the person more susceptible to depressive episodes.
  • Breast cancer : Use of the Tablet is not recommended in patients suffering from breast cancer.
  • Thromboembolism: Patients having cerebrovascular disease, a blood clotting disorder or active thrombophlebitis are advised to not administer the medicine.
  • Liver Disease: Use of the medicine is not recommended in patients with a history of the liver-related condition.
  • Retinal thrombosis: Consumption of the drug may cause side effects such as retinal vascular lesions, loss of vision, or blurred vision. The risk is higher in patients with a history of vision related problems. If any vision related problem is observed, it is advised to report the symptoms to the doctor immediately.
  • Fluid retention: The tablet should be administered with caution in patients suffering from edema or presence of excess fluid in the body.

Interaction with Medicines:

The Tablet may interact with the following drugs and products:

  • Acitretin
  • Amprenavir
  • Bexarotene
  • Boceprevir
  • Bosentan
  • Bridion
  • Etretinate
  • Fosamprenavir
  • Isotretinoin
  • Mycophenolic acid

Interaction with Lab Test:

  • Thyroid function tests: Inform the doctor about the use of Meprate tablet before undergoing thyroid function tests. The use of this drug may interfere with the results of the test.
  • Blood coagulation tests: It is important to inform the doctor about the use of Meprate tablet before taking a blood coagulation test. Use of this medicine may affect the test results.

Medicine Variants

Following are the two available variants of Meprate tablet:

  • Meprate 10 mg tablet
  • Meprate 2.5 mg tablet

Medicines that should not be taken with Meprate Tablet:

Following medicines are not recommended to be taken with Meprate tablet as it may cause adverse effects if taken in combination with Meprate tablet:

  • Amprenavir
  • Bexarotene
  • Boceprevir
  • Bosentan
  • Bridion
  • Etretinate
  • Mycophenolic acid
  • Fosamprenavir
  • Isotretinoin
  • Acitretin

How to Store Meprate?

  • Store the medicine in a cool and dry place away from sunlight below 25-degree Celsius.
  • Medicine should not be refrigerated.
  • Don’t flush the tablet unless not instructed to avoid contamination of the environment.
  • Keep it away from the reach of the children.
  • Keep it away from pets.

Frequently Asked Questions:

1) What is Meprate?

Ans: Meprate is a medicine which consists of a synthetic, steroid hormone that is similar to but not identical to progesterone, hence, it is a non-bio-identical hormone.

2) Can I take Meprate Tablet with Paracetamol?

Ans: It can be taken with Paracetamol. No interactions have been reported between the two. Please consult your doctor before taking the two medicines together.

3) Does Meprate Tablet cause ovulation or stops ovulation?

Ans: The tablet prevents follicular maturation and stops ovulation.

4) Does Meprate expire?

Ans: Yes, It has an expiry date and should not be used beyond the date which is mentioned on the package.

5) Is Meprate Tablet a birth control pill?

Ans: Yes, It may be used as a contraceptive. However, it should be used only if advised by your doctor.

6) What is Meprate tablet used to treat?

Ans: The tablet is used to treat and prevent conditions such as

  • Delaying Periods
  • Contraceptive
  • Amenorrhea
  • Endometrial Cancer
  • Endometriosis
  • Birth Control
  • Renal Cell Carcinoma
  • Menstrual Cramps
  • Heavy bleeding unrelated to periods
  • Heavy bleeding during periods (Menorrhagia)

7) What is Meprate tablet used for?

Ans: The tablet is used for treating irregular, painful or absent menstrual periods. This medicine also prevents overgrowth of the lining of the womb in the menopausal women taking estrogen.

8) What are the side effects of Meprate tablet?

Ans: Listed below are some of the side effects reported after the consumption of Meprate tablet:

  • Minor spotting or bleeding from the vagina
  • Irregular periods
  • Absence of menstrual bleeding
  • Pain in breasts
  • Abnormal milking from breasts
  • Heavy bleeding
  • Nervousness
  • Sleeplessness
  • Weakness, drowsiness, dizziness
  • Nausea
  • Loss of hair or abnormal growth of hair
  • Fever
  • Swelling
  • Vomiting
  • Abdominal cramps and bloating
  • Depression
  • Weight gain
  • Thrombophlebitis (inflamed veins)
  • Blood clot
  • Acne

9) Is it safe to take Meprate tablet during pregnancy?

Ans: The durg is highly unsafe to use during pregnancy.

10) Is Meprate tablet an antibiotic?

Ans: No, it is not an antibiotic. The medicine is contraceptive by nature which is used to treat abnormal, painful or absent periods.

11) Is Meprate tablet a painkiller?

Ans: No, it is not a painkiller. Meprate tablet is a progestin which helps in regulating menstrual cycles and ovulation in females.

12) What is the right time to take Meprate tablet?

Ans: It should ideally be consumed a couple of hours before having food to increase its efficacy.

13) When to avoid the consumption of Meprate tablet?

Ans: Meprate tablet should be avoided in the following conditions:

  • Breastfeeding
  • Pregnancy
  • Patients with bleeding disorder
  • Allergic
  • Hypersensitivity

14) What are the storage requirements for Meprate tablet?

Ans: Following are the storage requirements for Meprate tablet:

  • Store this medicine in a cool and dry place away from sunlight below 25 degree-celsius.
  • Keep it away from the reach of the children.
  • Keep it away from pets.
  • Don’t freeze the medicine.
  • Don’t flush the tablet unless not instructed to avoid contamination of the environment.

15) What are the medicines that should not be taken with Meprate tablet?

Ans: Listed below are the medicines that should not be taken with the drug to avoid the adverse effects:

  • Acitretin
  • Bridion
  • Etretinate
  • Amprenavir
  • Bexarotene
  • Fosamprenavir
  • Isotretinoin
  • Mycophenolic acid
  • Boceprevir
  • Bosentan

16) Is it safe to drive after the intake of Meprate tablet?

Ans: If you feel drowsiness, dizziness, a headache or hypotension as side effects of the Meprate tablet, then it is suggested to discontinue the medicine.

17) Is Meprate habit forming?

Ans: No, any habit-forming tendencies have been reported yet after taking Meprate tablet.

18) What if I missed a dose of Meprate tablet?

Ans: In case if you missed the dose it is suggested to take it as soon as you remember but if it’s already time to take another dose, it is suggested to skip the missed dose and continue Meprate tablet as per schedule.

19) What if I overdosed on Meprate?

Ans: In case you overdosed on Meprate, it is advisable to consult the doctor immediately.

20) Can I take Meprate tablet on empty stomach?

Ans: It is advisable to take the medicine at least 2 hours before or after having a meal with a glass full of water.

21) Can I take it with alcohol?

Ans: No, it is not advised to consume this tablet with alcohol as it may increase the risk of side effects.

Read More: Voveran | Wikoryl | Wysolone

Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

User Comments (2)

J

Jai

Thu Mar 28 2019

What is the dose for endomatrialsarcoma low grade /meprate20or40mg per day

Reply
NJ

Neha Jain

Fri Mar 29 2019

If i do not follow a fix time to take meprate., suppose one day i took the tablet after my shift ends morning and the other day i took at night at 12 am, will this be a problem Or will the meprate work?

Reply

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