MTP Kit: Uses, Side Effects, Composition, Dosages & Price

MTP Kit primarily helps women who are less than seven weeks pregnant and require abortion.  The kit is used with misoprostol. It is a synthetic steroid that functions to inhibit the hormones that support the pregnancy and subsequently leads to an abortion. It is also prescribed to women suffering from hormonal disorders and other problems. The MTP Kit is also known as RU-486. It is manufactured by Cipla.

MTP Kit

Uses and Benefits of MTP Kit:

The primary function of the MTP Kit is to terminate a pregnancy before two months has concluded, but may be used up to ten weeks.

However, it can also help in a number of other disorders, including:

  • It can induce menses
  • It can help with extensive blood loss problems
  • Labour induction in case of the death of the foetus, or in case the surgical procedure is required to save the mother.
  • Women with endometriosis may be recommended the use of MTP Kit
  • Patients who have Cushing's syndrome and insulin-dependent diabetes mellitus may require MTP Kit to manage their blood sugar levels.
  • It may also be used in breast cancer treatment, treatment of gastric ulcers, or duodenal ulcers, Meningioma, uterine leiomyoma or some gastrointestinal injuries.

Read More: Sinarest Uses | Stemetil Uses

Side Effects of MTP Kit:

As the MTP works primarily by inhibiting the progesterone levels, it has high chances of side-effects. While some side effects may be relatively mild, some side effects could be life-threatening. The conditions of the patients must be monitored closely and should consult the physician in case of persistent side-effects.

  • Excessive and persistent bleeding from the vagina, and painful menses
  • Uterine contractions or cramping in the hours following intake and abdominal pain
  • Uterine infections, or any other infection
  • Milder side-effects of MTP Kit are indigestion and insomnia, itching of the genital areas, etc. Persistence of these side effects may indicate infection, and the patient should consult a physician.

Read More: Nimesulide Side Effects | Pan D Side Effects

Common Dosage of MTP Kit:

It is not the same as i-pill; it is not an over the counter medicine and should absolutely not be taken without a physician’s prescription. The dosage will change depending on the patient’s health, age, weight, and other conditions. Self-prescription can lead to serious problems.

MTP is meant to be taken orally. The tablet should be allowed to dissolve by itself in the cheek. If any bit of it remains, it may be swallowed with water. The initial course is usually for a week, requiring a physician’s consultation after 7 days.

Read More: Thrombophob Gel Dosage | Teneligliptin Dosage

Composition and Nature of MTP Kit:

The active ingredients of the MTP Kit are Mifepristone and Misoprostol. MTP works by blocking the effects of progesterone.

How MTP Kit works?

It is a combination of two active ingredients, Mifepristone and Misoprostol.

Mifepristone works by blocking the effects of progesterone. It is required by the body to sustain a pregnancy. Progesterone makes sure that the lining of the womb does not break down as happens in a menstrual cycle. By inhibiting progesterone, uterine contractions will be induced, which will cause abortion.

When is MTP Kit prescribed?

It is used to terminate the pregnancy. Doctors prescribe this medicine to women who have been pregnant for 50 days or 7 weeks and want an abortion. The drug is also prescribed to manage blood sugar levels in patients suffering from Cushing’s syndrome.

Precautions and Warnings - When to Avoid MTP Kit?

There are a number of reasons that a doctor may advise a substitute instead of MTP. Inform your physician of any other medication or supplements (including homeopathic and ayurvedic medication) that you are taking at the same duration. You may be advised to take a different medicine if:

  • You have any prior allergies to the ingredients of the MTP.
  • Your other medications include some form of anticoagulants.
  • Your pregnancy is abnormal (ectopic) and may require a different procedure. Doctors also advise against it in case of surgical or dentistry procedure due in the foreseeable future, as it may interfere with aesthetic.
  • Higher risks are also present for those who are 35 years or older, smoke heavily (defined as more than ten cigarettes daily) and those who have liver, kidney, or lung diseases, or have asthma. If there is a chance of renal impairment or adrenal failure, the patient may be advised to use a different medication.
  • Patients with a history of the cardiovascular or cerebrovascular disease may be at risk of dangerous side-effects.

Substitutes of MTP Kit:

There are many substitutes present in the market but the Herwont Kit manufactured by Torrent Pharmaceuticals Ltd is popular. It has an identical composition; Mifepristone and Misoprostol. It can be used as a near-exact substitute for MTP.

Is MTP Kit Banned in India?

It is an abortion kit that has been banned in India for a long time.

How to store MTP Kit?

It is advisable to store MTP in a cool and dry place away from the reach of children and pets. The packaging of the medicine must be kept intact in order to maintain its effect when being administered

.

How to Check the Expiry Date?

Read the label carefully and check for manufacturing date and expiry date before consuming MTP.

When to Take MTP Kit?

MTP should never be taken on an empty stomach. It should always be taken with food. Taking this medicine with milk can minimize its side-effects.

How to Use MTP Kit Orally?

Follow the directions as directed on the leaflet inserted or as directed by the doctor. It is recommended to take this medicine with food and consume milk with it to minimize the side-effects.

MTP Kit for Pregnancy:

MTP should be used by women who want to terminate their pregnancy. For women, willing to terminate their pregnancy this medicine should be consumed in the first seven to nine weeks of pregnancy.

MTP Kit Interactions with other drugs:

  • Grapefruit juice: Grapefruit juice interacts with the activity of MTP and large quantities of grapefruit juice may alter the amount of MTP in the blood.
  • Hydrocortisone: Doctors will generally alter one or the other medication, as it is not recommended to use hydrocortisone and mifepristone at the same time. If you are taking both, then consult your doctor before stopping the use of either medication.
  • Dexamethasone: consuming this medicine along with MTP, or any medication with mifepristone is not recommended. It may require dose adjustment and the patient will need to be monitored by the doctor.
  • Erythromycin and Pimozide: Using MTP concurrently with erythromycin or pimozide may increase the risk of heart diseases or result in changes in the electrolyte levels of the body.
  • Ketoconazole: consuming this medicine with MTP will require adjustment of doses and close monitoring of the patients.
  • Ergotamine: It will increase the risk of a stroke by impeding blood flow, and physicians don’t recommend the consumption of ergotamine at the same duration as MTP.
  • Simvastatin: The risk of dangerous side-effects of consuming Simvastatin along with MTP is high.
  • Warfarin: Any medicine consumed by women to deal with mensuration problems may lead to adverse effects when consumed with MTP. The risk is high, and either a change of medicine or close monitoring is required.

FAQs:

1) Can I take the MTP Kit for any reason while breastfeeding?

Ans: As It has a direct effect on the hormones that regulate pregnancy, it is recommended that women use a different medicine when breastfeeding.

2) What is MTP Kit used for?

Ans: It is generally used for terminating a pregnancy up to seven weeks. It may also be used to manage breast cancer, extra uterine pregnancy and blood sugar levels in patients suffering from Cushing’s syndrome.

3) What is MTP Kit?

Ans: This Kit is a synthetic steroid which is used in combination with misoprostol to terminate the pregnancy. The drug interferes with the hormones to produce desired results.

4) What are the side effects of MTP Kit?

Ans: It shows a number of side-effects. Some of the side-effects include heavy vaginal bleeding, abdominal cramps, decreased appetite, nausea, and painful breathing.

5) Is MTP Kit safe to use?

Ans: This drug is not safe to use and hence should be avoided. It is even banned in India for a long time.

6) Is MTP Kit a steroid?

Ans: Yes, it is a synthetic steroid that aids in medical abortion.

7) How does MTP Kit work?

Ans: MTP interferes with hormones to terminate 50 days of pregnancy. This drug blocks the effect of a hormone called progesterone by competitively binding to the specific receptors and sensitizing the inner linings of the uterus inducing bleeding and contractions. MTP also blocks the effect of cortisol at the particular receptors and reducing the effect caused by an excess of this hormone thereby producing the desired results.

8) Can I take MTP Kit with alcohol?

Ans: Though no interactions have been reported between MTP Kit and alcohol, it’s not advisable to consume it with alcohol as it can result in increased side-effects.

9) Can I take MTP Kit with Aspirin?

Ans: No, several interactions have been reported between aspirin and MTP Kit and hence it is not advisable to consume it with aspirin.

10) Can MTP Kit cause serious side-effects?

Ans: I t is a strong medicine that may cause serious side-effects and hence should not be used without consulting a doctor. The drug is even banned in India.

11) When to take MTP Kit?

Ans: MTP Kit should always be consumed after having a meal. It is recommended to consume this drug with milk to minimize its side-effects.

12)  What precautions should be considered before taking MTP Kit?

Ans: Before taking the medicine, talk to your doctor about the current list of medications, and pre-existing health issues. Do not mix MTP Kit with smoking or alcohols.

13)  When should the use of MTP Kit be avoided?

Ans: The Medicine should be avoided in case of irregular menses, lactation, kidney or liver-related disorder and hypertension.

14) Is bleeding normal after consuming MTP Kit?

Ans: Yes, It is an abortion kit that induces vaginal bleeding. Bleeding may start within four to five hours of consuming the pill and may last for a period of 21 days.

15) What is the success rate of abortion through MTP Kit?

Ans: The success rate of getting an abortion through MTP Kit is 8% to 46%. However, if taken within the seven weeks of pregnancy, the success rate is 92%. The kit results in abortion within 14 days of using it.

16) How do you take MTP kit pills?

Ans: The MTP kit includes Misoprostol pill and Mifepristone. It should be taken as following:

  • 200 milligrams (mg) of Mifepristone tablet should be taken to stop the progression of pregnancy.
  • The patients should wait for 24-48 hours.
  • After 3 days, four tablets of misoprostol should be consumed either orally or sublingually (under the tongue). The medicine can be taken by vaginal route as well.

It is advised to undergo a medical examination after 14 days of medicine ingestion to confirm termination of pregnancy with clinical tests.

17. For how long does one bleed after consuming MTP kit?

Ans: Bleeding generally starts after four hours of consuming MTP kit. Bleeding is usually heavier than in the normal mensuration. Usually, the bleeding continues lightly for one to three weeks after the abortion but may vary from person to person.

18. Should mifepristone be taken on an empty stomach?

Ans: Yes, mifepristone should be taken on an empty stomach. Alternatively, this medicine can be consumed at least 2 hours before or after a meal.

19. Are there any reported Allergic Reactions of MTP kit?

Ans: Yes, there are few allergic reactions such as dizziness, rash, trouble breathing, itching, swelling of the tongue, face and throat, etc. However, there are no severe allergies.

It is advised to consult a doctor if any undesired effect is experienced.

20. What happens if I eat an expired does of MTP Kit?

Ans: An expired dose of MTP kit will not provide an effective result. Also, it may show an adverse effect on the health of the woman.  It is advised to consult a gynecologist as soon as possible.

21. What happens if I miss a dose of MTP Kit?

Ans: The desired result will not be achieved. Also, it is advised to consult a medical practitioner immediately.

22. How frequently should I take MTP Kit?

Ans: MTP Kit is an emergency abortion pill and should not be used as a birth control pill. Using this medicine frequently can effect the fertility of a woman or result in painful periods. It is advised to consult a doctor if a woman has to take the medicine twice within a span of a year.

Read More: Clavam 625 | Evion-400 | Primolut N

Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

Leave a Comment