Naxdom 250 Tablet: Uses, Side Effects, Composition & Dosages

Naxdom 250 tablet belongs to the class of drugs known as a non-steroidal anti-inflammatory drug. The medicine is used to treat migraine attacks, osteoarthritis, and rheumatoid arthritis. It works by blocking the dopamine receptors in the body that reduces the production of prostaglandins. The medicine is manufactured by Sun Pharmaceutical Industries Ltd.

Nature: Non-Steroidal Anti-Inflammatory Drug
Uses: Acute gout, rheumatic disorders, dysmenorrhoea and menstrual cramps
Composition: Domperidone and Naproxen
Side effects: Dry mouth, indigestion, stomach pain
Precautions: Pregnancy, driving, kidney and liver disease

Composition & Nature of Naxdom 250 Tablet:

Naxdom 250 is a non-steroidal anti-inflammatory drug. It is composed of two major ingredients:

  • Domperidone (10 mg)
  • Naproxen (250 mg)

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Uses & Benefits of Naxdom 250 Tablet:

Naxdom 250 is used in the treatment of the following diseases:

  • Acute gout
  • Acute Musculoskeletal disorders
  • Rheumatic disorders
  • Dysmenorrhoea
  • Menstrual cramps
  • Ankylosing spondylitis
  • Arthritis
  • Tendinitis
  • Antipyretic
  • Analgesic
  • Juvenile idiopathic arthritis
  • Osteoarthritis

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Side Effects of Naxdom 250 Tablet:

Some of the most common side effects associated with the consumption of Naxdom 250 are:

  • Dizziness
  • Fainting
  • Dry mouth
  • Nausea
  • Constipation
  • Lightheadedness
  • Stomach ache
  • Heartburn
  • Bleeding
  • Difficulty in swallowing
  • Mood changes
  • Ringing in the ears
  • Eczema
  • Cephalalgia
  • Somnolence

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Common Dosage of Naxdom 250 Tablet:

There is no fixed dosage of Naxdom 250. The dose of the medicine varies with the condition of the patient, age, weight, gender etc. This medicine should be administered orally; 2 or 3 times in a day.

It is instructed that one must not lie down immediately after taking Naxdom 250 tablet and wait for at least 10 minutes before getting up. The medicine must be taken with food, antacid or milk, to prevent the stomach from getting upset.

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How to use Naxdom 250?

Naxdom 250 Tablet should be taken orally as prescribed by the doctor, at least twice or thrice in a day. Remember not to lie down for at least 10 minutes after taking the medicine.

In order to avoid loose motions, take Naxdom 250 with food, milk or an antacid. To reduce the chances of side effects, take this medicine at the lowest effective dose for some time. High uses of the medicine should be taken under medical supervision only.

Before starting the course of Naxdom 250, patients should inform the doctor about their medical history, the current list of medicines being consumed and if they are to undergo surgery.

Some health conditions may make patients more susceptible to the side-effects of the particular medicine.

How Naxdom 250 Tablet Works?

Naxdom 250 works by blocking the dopamine receptors in the body. When the dopamine receptor is blocked, there is a decrease in the effect of cyclooxygenase enzyme, which ultimately reduces the production of prostaglandins. Naxdom 250 tablet reduces the hormones responsible for causing inflammation or pain.

When Naxdom 250 is prescribed?

Naxdom 250 is a non-steroidal anti-inflammatory drug (NSAID) which works by reducing the hormones that causes pain and inflammation in the body.

Naxdom 250 is prescribed for the treatment of the following conditions:

  • Arthritis: This condition causes pain and swelling in the joints. Some kinds of arthritis can develop problems in organs like eyes and skin. Osteoarthritis and rheumatoid arthritis are the most common types of arthritis. Naxdom 250 reduces the hormones that cause pain and inflammation.
  • Tendinitis: This condition is an inflammation of a tendon, a cord that attaches bone to muscles. It is caused by repetitive and sudden injury. It occurs at the base of the thumb, elbow or knees.
  • Gout: People with high levels of uric acid in their bloodstream may develop inflammatory arthritis known as gout. This condition causes joint pain, swelling, and redness. It usually occurs in toes, ankle, and elbow. Due to its analgesic and anti-inflammatory properties, Naxdom 250 is used for curing gout.
  • Bursitis: It is a painful condition affecting small and fluid-filled sacs, called bursae, which covers the bones, tendons, and muscles around the joints. It is common in the shoulder, elbow, and hip. It is associated with diabetes, rheumatoid arthritis, and gout.
  • Menstrual cramps: NSAIDs are highly effective in treating menstrual pain. As Naxdom 250 is an NSAID, it helps in providing relief from menstrual cramps.
  • Vomiting: Naxdom 250 contains domperidone that works by controlling neurotransmitter dopamine, a chemical messenger present in the body, from acting on the vomiting center in the brain. This action prevents vomiting.

Warnings and Precautions Related to Naxdom 250 Tablet:

The following precautions and warnings must be adhered to while administering Naxdom 250:

  • Patients allergic to any of the ingredients present in the medicine must refrain from administering it.
  • Alcohol has been found to alter the absorption capacity of Naxdom 250 by the body. Hence, it is advised not to consume alcohol while taking this medicine.
  • Doses should be taken in the quantity prescribed by the doctor; neither less, nor more.
  • Avoid driving or working on heavy machinery just after consuming Naxdom 250, as it may cause drowsiness and dizziness.
  • Patients suffering from stomach ulcers and kidney disorder are advised not to administer this medicine.

Substitutes for Naxdom 250 Tablet:

Below is the list of medicines, which have the same composition, strength, and form as Naxdom 250 Tablet, and hence can be used as its substitute.

  • Naprodom 250 Mg Tablet
  • Napra D 250 Mg Tablet
  • Pandex Tablet
  • Clofenac 50 MG Tablet
  • Minado 250 Tablet
  • Macprox DP 250 Tablet
  • Naprodom 250mg Tablet
  • Xenadom 250 Tablet
  • Pandex Tablet
  • Comig 250 Tablet
  • Xendom 250 mg/10 mg Tablet
  • Naprolet DS 250 mg/10 mg Tablet
  • Naplon-D Tablet
  • Naprosyn D 250 mg/10 mg Tablet
  • Freedonap 250 mg/10 mg Tablet

Naxdom 250 Tablet Interactions:

Naxdom 250 has been found to interact with many drugs and diseases. Hence, it is advised that patients must consult the doctor and disclose all the information related to the medicines they are currently taking and their medical history.

Some of the drugs with which Naxdom 250 has established interaction are:

  • Antacids
  • Amprenavir
  • Aluminium hydroxide
  • Clarithromycin
  • Bisoprolol
  • Ciprofloxacin
  • Atropine
  • Aprepitant
  • Amiodarone
  • Atazanavir

Naxdom 250 Variants

The medicine is only available in the following variant:

Medicines that should not to be taken with Naxdom 250:

Taking a certain medicine or over-the-counter product at the same time may alter the effects of Naxdom 250. This may increase the risk of side effects or it is possible that the medicine may not show the desired results. Mentioned below is the list of medicines that should not be taken with Naxdom 250:

  • Amprenavir
  • Antacids
  • Atazanavir
  • Atropine
  • Bisoprolol
  • Ciprofloxacin
  • Diltiazem
  • Erythromycin
  • Fluconazole
  • Furosemide
  • Itraconazole
  • Ketoconazole
  • Lithium
  • Magnesium oxides and hydroxides
  • Methotrexate
  • Nefazodone
  • Phenytoin
  • Propranolol
  • Ranitidine
  • Ritonavir
  • Warfarin

Naxdom 250 Price in India:

Medicine variant Price(Quantity)
Naxdom 250 Tablet INR 72(Strip of 10 tablets)
Naxdom 250 Tablet INR 55(Strip of 10 tablets)

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How to store Naxdom 250?

Naxdom 250 tablet should be stored at room temperature, away from heat and direct light. It is advised to keep the medicines away from the reach of children and pets.


1) Is it safe to use Naxdom 250 during pregnancy?

Ans: No, this medicine is not safe to use during pregnancy. Hence, it is not recommended to be taken unless prescribed by a doctor. For usage of Naxdom 250, always rely on the doctor’s prescription.

2) For what purpose is the Naxdom 250 Tablet generally used?

Ans: Naxdom 250 Tablet is generally used for the treatment of an acute migraine attack. It is given to the patients as an analgesic. For dosage and usage of Naxdom 250, always rely on the doctor’s discretion and prescription.

3) In how much time can we expect Naxdom 250 to start working on the body?

Ans: The users of Naxdom 250 have reported that they start to observe the effect of the medicine on the body within 2 hours of its intake or maximum after 24 hours.

4) For how many times a day and for how long is Naxdom 250 prescribed to be taken?

Ans: Usually, doctors suggest that Naxdom 250 should be taken once in a day for as long as the condition persists. Take this medicine in the dose and duration as prescribed by your physician.

5) How should Naxdom 250 be taken – with meals, after meals or before meals?

Ans: The medicine can be taken with or without meals. But, for best results, it is advised to take this medicine after meals.

6) Is it safe to drive or work on heavy machinery, immediately after taking the Naxdom 250 Tablet?

Ans: No, Naxdom 250 is not recommended if one feels dizziness, hypotension, drowsiness, headache or numbness, just after taking the medicine.

7) Can the consumption of the Naxdom 250 be stopped abruptly after one sees improvement in his or her condition?

Ans: No, you must not stop the intake of any medicine abruptly, as some medicines have some rebound effects, if stopped abruptly. Doctor’s discretion and words for the dosage should be considered final.

8) Is the nature of Naxdom 250 addictive?

Ans: No, the nature of Naxdom 250 is not addictive. To be on a safer side, it is advised to read the packaging of the medicine for all the related information.

9) Is it safe to consume alcohol while on the course of Naxdom 250?

Ans: No, drinking alcohol while on the course of the medicine is not recommended as it may increase the risk of adverse effects such as dizziness and headache. The interaction reduces the absorption of Naxdom 250 by the body, and it may also cause some stomach bleeding. Hence, it is advisable that you must refrain from consuming alcohol while you use Naxdom 250 tablet.

10) Has Naxdom 250 been found to affect the liver-related functions?

Ans: Patients suffering from impaired liver function must exercise caution when consuming Naxdom 250, as it can cause unwanted side effects. The physician may ask the patient to take this medicine in small amounts.

11) Is Naxdom 250 used for treating headache or migraine?

Ans: No, Naxdom 250 does not cure migraine, but it can control migraine attacks by decreasing the symptoms of prostaglandins that are responsible for causing pain.

12) Is it safe to stop the course of medication on my own or should doctor’s advice be followed?

Ans: Naxdom 250 should not be discontinued unless advised by the doctor. Since it is a prescription drug, it is advised to stop the course of the medication only after consulting your doctor.

13) Can I consume alcohol during the course of Naxdom 250?

Ans: Yes, drinking alcohol in moderation does not cause any harm. However, high doses or long-term use of the medicine can cause irritation in the stomach lining, and drinking excessive alcohol can be harmful.

14) What is the recommended dose of Naxdom 250?

Ans: If you are taking Naxdom 250 for menstrual pain, without a prescription; then it is suggested to take 2 tablets, 250 mg on the first day and 250 mg after 6-8 hours, on the same day. One should not take more than 3 doses of Naxdom 250 tablet in a day.

15) Is Naxdom 250 banned in India?

Ans: No, Naxdom 250 tablet is readily available in India.

16) How should I take Naxdom 250 tablet?

Ans: The medicine should be taken with meals or after meals as it helps in avoiding indigestion and abdominal pain. While this is the common dosage instruction for this medicine; the doctor’s advice should be followed to avoid side effects.

17) What are the medicines that can negatively interact with Naxdom 250 mg tablet?

Ans: Mentioned below is the list of medicines that can negatively interact with Naxdom 250mg Tablet:

  • Adefovir
  • Betrixaban
  • Bromocriptine
  • Diltiazem
  • Fluoxetine
  • Gatifloxacin
  • Ketoconazole
  • Phenelzine
  • Selegiline

18) What will happen if I consume an expired dose of the medicine?

Ans: Taking a single dose of an expired medicine will not cause any harm. However, if by mistake a patient takes an expired medicine, he or she should immediately consult a doctor. Patients should always check the expiry dates written on the packaging of the medicine before consumption.

19) What are the possible contraindications associated with the administration of Naxdom 250?

Ans: People hypersensitive to the following conditions should not administer this medicine:

  • Peptic ulcer
  • Gastrointestinal bleeding
  • Congestive heart failure
  • Pregnancy
  • Gastrointestinal blockage
  • Gastrointestinal hemorrhage

20) What are the important things to keep in mind while using Naxdom 250 tablet?

Ans: Mentioned below are some of the important things to keep in mind while taking this medicine:

  • It is advised not to take this medicine to treat an acute attack of migraine.
  • Avoid consumption of alcohol as it may cause drowsiness.
  • Take this medicine as prescribed by the doctor even if you notice an improvement in your symptoms.

21) Does Naxdom 250 tablets have any adverse effects on kidneys?

Ans: The medicine should be used with caution by patients suffering from kidney diseases, as it can worsen the symptoms. Hence, it is advised that patients suffering from kidney related ailments should use this medicine only after consulting a doctor.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

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