Nexito Plus Tablet: Uses, Side Effects, Composition, Price & Dosages

Nexito Plus Tablet is used for the treatment of a host of mental health problems, particularly anxiety, panic, and Major Depressive Disorders. Nexito Plus is also used for the treatment of various illnesses such as seizures. It is known as anti-epileptic and anti-seizure.

Nature of Nexito Plus Tablet: Anti-anxiety and anti-convulsant
Composition of Nexito Plus Tablet: Clonazepam, Escitalopram
Uses of Nexito Plus Tablet: Anxiety disorder, Treatment of panic attack, depression , major depressive order, Agitation, Treatment of panic disorder
Side effects of Nexito Plus Tablet: Drowsiness, dry mouth, skin rash , dizziness , insomnia.weight loss or weight gain, constipation, vertigo, dull headache, ejaculation disorder, memory loss, appetite loss and more.
Precautions of Nexito Plus Tablet: Liver-related disorder, Narrow-angle glaucoma, allergic reactions to Benzodiazepine, irregular heartbeat, difficulty in sitting and more.
Nexito Plus Tablet

Nexito Plus Tablet contains Clonazepam and Escitalopram as active ingredients. Nexito Plus is manufactured by well-known pharmaceutical company Sun Pharma in India.

Uses and Benefits of Nexito Plus:

Nexito Plus works by increasing the serotonin content of the brain and is thus used to treat many neurological and mental health disorders that are suspected to be caused by a low level of serotonin.

  • Nexito Plus is used in the treatment of panic disorders, Major depressive disorder, Anxiety disorders
  • Nexito Plus Tablet is also used to treat problems that cannot yet be classified as disorders according to the DMV, including anxiety, depression, and agitation that is severe enough to impair quality of life or normal functioning.
  • Nexito Plus is used for the treatment of seizure disorder

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Side Effects of Nexito Plus:

Nexito Plus has several commonly occurring side-effects that are usually not very severe. Common but low-impact side-effects may include general drowsiness, headache or low-level fatigue, insomnia, skin rash, dizziness, and constipation .

  • Patients may also face ejaculation disorder or dampening of the libido from Nexito Plus
  • Some patients may become confused
  • Some patients may experience adverse reaction that leads to vomiting
  • Patients may also have blurry vision or abnormal eye movements
  • Long-term use of Nexito Plus may cause dependency

While this is intended to help with depression, it may work contrary to indications in certain patients. Some patients may feel more depressed or become strongly suicidal. Such patients should be monitored closely, and the doctors should be informed immediately in case any signs of ill-effects are noted. The patient should not stop the medication without doctor’s consent as it may cause severe adverse effects.

Other Uncommon side effects of Nexito Plus Tablet are:

  • Rashes
  • Itching
  • Disturbed sleep
  • Taste disturbance
  • Loss of hair
  • Enlarged pupils
  • Visual disturbance
  • Fainting
  • Ringing in the ears
  • Agitation
  • Nervousness
  • Panic attack
  • Confusion state

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Common Dosage of Nexito Plus:

The dosage of Nexito Plus may vary widely, depending on the medical condition, the overall health of the patient, the longevity of their condition, their age, and many other factors. It may take some trial and error before the doctor finds the most appropriate dosage to help the patient without causing any side-effects.

On no account should any patient consider self-treatment with Nexito Plus or any similar medicines. They should also neither increase their dosage without informing their physician nor should they stop taking Nexito Plus Tablet without medical supervision.

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Composition & Nature of Nexito Plus:

Nexito Plus has two active ingredients; Escitalopram and Clonazepam.

Nexito Plus Price in India:

  • A strip of 10 tablets:  81.00 INR

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When Nexito Plus is prescribed?

  • Panic attacks: Nexito Plus Tablet is very effective in the prevention and management of panic attacks related to episodes of anxiety if present.
  • Seizure disorder: Nexito Plus is used in the prevention and management of the different type of seizures.
  • Sleep disorders: Nexito Plus Tablet is very effective in the treatment of a specific sleep disorder known as REM Sleep Behaviour Disorder

How to use Nexito Plus?

It is advisable to consult a doctor for the appropriate dosage of Nexito Plus. Don’t take less than or more than the prescribed dose. Nexito Plus Tablet is well absorbed if taken orally. Nexito tablet can be taken with or without food.

Nexito Plus should be swallowed whole with plenty of fluids. Don’t crush, chew or break the tablet. It is advisable not to stop Nexito Plus in between or before the course of the therapy is completed. Consult a doctor before doing so. Nexito Plus should not be used as an over the counter drug. It is recommended to consult a doctor before taking Nexito Plus Tablet.

How Nexito Plus works?

Nexito Plus Tablet works by improving the activity of serotonin in the brain, which is believed to have a strong effect on mood. Nexito Plus Tablet works by enhancing the activity of gamma-aminobutyric acid (GABA) neurotransmitter which is responsible for the activity of serotonin.

Warnings/Precautions- When to avoid Nexito Plus Tablet?

  • Patients who are allergic to the Benzodiazepine group of drugs should not take Nexito Plus, which is a sub-group of this family.
  • Patients with a history of the liver are advised to not use Nexito Plus.
  • Patients using Nexito Plus are warned not to drive vehicles or use heavy machinery as it may cause drowsiness.
  • Alcohol and other drugs should not be taken while using Nexito Plus, as the combination may have a strong ill effect on the health of the patient.
  • Patients with a history of seizures may find that their seizures are getting worse. They should consult their doctor for an appropriate course of action.
  • If taking Nexito Plus Tablet causes difficulty in sitting or urination, then the patient should inform their doctor immediately and discuss their options.
  • If the patient feels that their breathing is irregular, they are having trouble breathing, or that their heartbeat is not regular, and then they may be having an allergic reaction or a bad side-effect. The patient should be monitored and the doctor should take action.
  • Patients with pre-existing respiratory problems may not be able to take Nexito Plus Tablet and will need monitoring and periodic readjustment of dosage if they do use it.
  • Nexito Plus is not recommended for use if the patient has Acute Narrow-Angle Glaucoma in particular, whereas those with Open Angle Glaucoma usually don’t face any issues.
  • Avoid abrupt discontinuation of this drug so as to prevent any existing problem from becoming overwhelming. It may also result in withdrawal symptoms including (but not limited to) seizures, mood swings, appetite problems, and others.
  • In rare cases, usually, patients with a history of substance abuse problems, the use of Nexito Plus Tablet may cause addiction. Patients who have had a substance abuse problem previously, particularly that left untreated advised to get a consultation from their physician regarding their options.
  • Long-term use may reduce the effectiveness of Nexito Plus, and patients may need higher doses or a different medicine.

Nexito Plus Interactions:

All drugs interact differently and its effect varies from person to person. It is advisable to check all the possible interactions with the doctor before starting any medication.

Interaction with Alcohol:

Consumption of alcohol is not recommended during treatment with Nexito Plus as it may increase the risk of serious side effects including drowsiness, dizziness, difficulty concentrating, breathing difficulties, etc.

Interaction with Medicine:

There are various medicines that should not be taken with Nexito Plus to avoid adverse reactions:

  • Lithium
  • Carbamazepine
  • Tryptophan
  • Buprenorphine, disulfiram
  • Moclobemide (used to treat depression).
  • Selegiline (used to treat Parkinson’s disease).
  • The antibiotic linezolid
  • Doxycycline, Erythromycin, Itraconazole
  • Theophylline.
  • Sumatriptan (used to treat migraine)
  • Tramadol (used to treat severe pain).
  • Cimetidine, omeprazole
  • Butyrophenone classes of antipsychotic agents
  • Ticlopidine
  • Warfarin, dipyridamole, and phenprocoumon
  • Mefloquin (used to treat Malaria),
  • Imipramine, desipramine, bupropion, clomipramine, fluvoxamine and nortriptyline (used to treat depression)
  • Neuroleptics (medicines to treat schizophrenia, psychosis)
  • Flecainide, propafenone, and metoprolol (used in cardiovascular diseases)
  • Risperidone, thioridazine, and haloperidol (antipsychotics).
  • Medicines that decrease blood levels of potassium or magnesium
  • Non-selective monoamine oxidase inhibitors (MAOIs) containing phenelzine, iproniazid, isocarboxazid, nialamide, and tranylcypromine as active ingredients
  • St. John’s Wort (Hypericum perforatum) – an herbal remedy used for depression.
  • Acetylsalicylic acid and non-steroidal anti-inflammatory drugs (medicines used for pain relief or to thin the blood, so-called anticoagulant).

Interaction with Disease:

  • Closed-Angle Glaucoma: Nexito Plus is not recommended for use in patients with a known history of Closed-Angle Glaucoma. The usage of Nexito Plus Tablet may increase the risk of worsening of the patient's condition. It is advisable to consult a doctor and replace the drug with a suitable alternative.
  • Seizure disorders : Nexito Plus should be taken with extreme caution in patients with a known history of seizure disorders. The usage of Nexito Plus Tablet may increase the risk of worsening of the patient's condition. If the patient develops seizures or if there is an increase in the frequency of seizures in patients with a previous diagnosis of epilepsy, it is advisable to consult a doctor and replace the drug with a suitable alternative.
  • Respiratory disorders: Nexito Plus Tablet must be taken with caution in patients with a known history of respiratory disorders. The consumption of the drug may worsen the patient's condition. Close monitoring of lung function is recommended for such patients. It is advisable to consult a doctor and replace the drug with a suitable alternative.

Substitutes for Nexito Plus:

Common substitutes using Escitalopram and Clonazepam in the treatment of neurological or mental health disorders include:

  • Citajoy Tablet which is manufactured by Wings Biotech Ltd
  • Es Ok Plus Tablet manufactured by Eisai Pharmaceuticals India Pvt Ltd

They have the same composition as Nexito Plus and are equally effective in many cases.

Medicines that should not be taken with Nexito Plus Tablet:

Listed below are some of the medicines that should not be taken as combination with Nexito Plus tablet:

  • Lithium
  • Butyrophenone classes of antipsychotic agents
  • Carbamazepine
  • Tryptophan
  • Buprenorphine, disulfiram
  • Moclobemide (used to treat depression).
  • Selegiline (used to treat Parkinson’s disease).
  • The antibiotic linezolid
  • Doxycycline, Erythromycin, Itraconazole
  • Theophylline.
  • Sumatriptan (used to treat migraine)
  • Tramadol (used to treat severe pain).
  • Cimetidine, omeprazole
  • Ticlopidine
  • Warfarin, dipyridamole, and phenprocoumon
  • Mefloquin (used to treat Malaria),
  • Imipramine, desipramine, bupropion, clomipramine, fluvoxamine and nortriptyline (used to treat depression)
  • Neuroleptics (medicines to treat schizophrenia, psychosis)
  • Flecainide, propafenone, and metoprolol (used in cardiovascular diseases)
  • Risperidone, thioridazine, and haloperidol (antipsychotics).
  • Medicines that decrease blood levels of potassium or magnesium
  • Non-selective monoamine oxidase inhibitors (MAOIs) containing phenelzine, iproniazid, isocarboxazid, nialamide, and tranylcypromine as active ingredients
  • St. John’s Wort (Hypericum perforatum) – an herbal remedy used for depression.
  • Acetylsalicylic acid and non-steroidal anti-inflammatory drugs (medicines used for pain relief or to thin the blood, so-called anticoagulant).

How to store Nexito Plus?

  • Store Nexito Plus in a cool and dry place away from heat, sunlight, and moisture.
  • Don’t freeze or refrigerate Nexito Plus.
  • Don’t flush Nexito Plus Tablet until instructed.
  • Keep Nexito Plus away from the reach of the children.
  • Keep Nexito Plus Tablet away from pets.

FAQs

1) What is Nexito Plus used to treat?

Ans: Nexito Plus belongs to the class of anti-epileptic and anti-seizure drugs. Nexito Plus Tablet is used to treat mental health problems; particularly anxiety, panic, and Major Depressive Disorders. It is also used for the treatment of various illnesses such as seizures.

2) What is Nexito Plus Tablet used for?

Ans: Nexito Plus tablet is used to prevent and treat conditions such as

  • Anxiety
  • Major depressive disorder
  • Treatment of seizure disorder
  • Agitation
  • Panic disorder
  • Treatment of panic disorder
  • Anxiety disorder
  • Depression

3) What are the side effects of Nexito Plus?

Ans: Listed below are the various side effects of Nexito Plus, if any of these are experienced please consult a doctor.

  • Constipation
  • Drowsiness
  • Weight loss or gain
  • Vertigo
  • Dull headache
  • Ejaculation disorder
  • Insomnia
  • Dry mouth
  • Skin rash
  • Dizziness

Other Uncommon side effects of Nexito Plus Tablet are:

  • Rashes
  • Itching
  • Fainting
  • Ringing in the ears
  • Agitation
  • Nervousness
  • Panic attack
  • Confusion state
  • Disturbed sleep
  • Taste disturbance
  • Loss of hair
  • Enlarged pupils
  • Visual disturbance

4) When to Avoid Nexito Plus Tablet?

Ans: Nexito Plus Tablet should be avoided or used with caution in following conditions to avoid adverse effects:

  • Patients with allergy to any of its components
  • History of epilepsy
  • Decreased level of sodium in the blood
  • Pregnant Woman
  • Breastfeeding women
  • History of glaucoma
  • Alcohol intoxication
  • Diabetics
  • Patients with severe kidney and liver disease
  • Patients with or have had an episode of abnormal heart rhythm
  • Heart diseases

5) Which medicine may interact with Nexito Plus?

Ans: Following are some of the medicine that may interact with Nexito Plus and may cause adverse effects:

  • Buprenorphine, disulfiram
  • Lithium
  • Butyrophenone classes of antipsychotic agents
  • Carbamazepine
  • Tryptophan.
  • Sumatriptan (used to treat migraine)
  • Tramadol (used to treat severe pain).
  • Cimetidine, omeprazole
  • Ticlopidine
  • Warfarin, dipyridamole, and phenprocoumon
  • Mefloquin (used to treat Malaria),
  • Moclobemide (used to treat depression).
  • Selegiline (used to treat Parkinson’s disease).
  • The antibiotic linezolid
  • Doxycycline, Erythromycin, Itraconazole
  • Theophylline
  • Non-selective monoamine oxidase inhibitors (MAOIs) containing phenelzine, iproniazid, isocarboxazid, nialamide, and tranylcypromine as active ingredients
  • St. John’s Wort (Hypericum perforatum) – an herbal remedy used for depression.
  • Acetylsalicylic acid and non-steroidal anti-inflammatory drugs (medicines used for pain relief or to thin the blood, so-called anticoagulant).
  • Imipramine, desipramine, bupropion, clomipramine, fluvoxamine and nortriptyline (used to treat depression)
  • Neuroleptics (medicines to treat schizophrenia, psychosis)
  • Flecainide, propafenone, and metoprolol (used in cardiovascular diseases)
  • Risperidone, thioridazine, and haloperidol (antipsychotics).
  • Medicines that decrease blood levels of potassium or magnesium.

6) Does Nexito Plus have any addictive aptitude?

Ans: No, addictive aptitude has been reported yet.

7) Is there any food item that should be avoided while consuming Nexito Plus Tablet?

Ans: No, there is no particular food item that should be avoided while taking Nexito Plus. It is suggested to consult a doctor before the intake of Nexito Plus.

8) Can I take Nexito Plus with alcohol?

Ans: No, it’s better not to take the Nexito Plus with alcohol. Consumption of medicine with alcohol may cause liver damage. It is advisable to consult a doctor before administering Nexito Plus.

9) What are the storage requirements for Nexito Plus Tablet?

Ans: Following are the storage requirements for Nexito Plus:

  • Store Nexito Plus in a cool and dry place.
  • Don’t freeze or refrigerate.
  • Don’t flush until instructed.
  • Keep it away from the reach of the children.
  • Keep it away from pets.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

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