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Norflox TZ Tablet : Uses, Side Effects, Substitute & Dosages


What Is Norflox TZ?

Norflox TZ belongs to the class of quinolone antibiotics. It helps inhibits the continuous growth of bacteria and parasites thus preventing bacterial infections. Also, Norflox TZ is prescribed for the treatment of bacterial infections in the stomach, skin, urinary tract and vagina.

Norflox TZ is manufactured by Cipla Limited and is an over-the-counter medicine. However, it is advised to consult a doctor before consuming Norflox TZ to avoid interactions.

Norflox TZ consists of Tinidazole and Norfloxacin as main ingredients. These ingredients are found to be effective in the treatment of different types of bacterial infections.

Basically, Norflox TZ is an anti-bacterial drug strictly used for the treatment of bacterial infections of brain, skin or GI tract. Norflox TZ is not advised to be used for the treatment of viral infections. Patients should ensure that the course of Norflox TZ is completed. Stopping the course of Norflox TZ may result in resurfacing of the bacterial infections.


Nature of Norflox TZ- Antibiotic
Composition of Norflox TZ-   Norfloxacin and Tinidazole
Uses of Norflox TZ- Urinary tract infections, vaginal infections and skin infections
Side-effect of Norflox TZ- Constipation, weakness, gas, cramps
Precautions of Norflox TZ- People with issue of seizure and epilepsy should not use the Norflox. 


 What is the Uses and benefits of Norflox TZ?

Norflox TZ belongs to the class of antibiotics and is found to be effective in the prevention and treatment of bacterial infections. The salts present in Norflox works by inhibiting the growth of bacteria as well as killing them. 

Here is a list of conditions that the Norflox TZ is used for:

Vaginosis: It is a bacterial infection in which there is an overgrowth of bacteria in the vagina. The overgrowth is caused by Lactobacillus species. Tinidazole present in the medicine helps in the prevention and treatment of this condition.

  • Amebiasis: It is a parasitic infection that affects the liver. Amebic liver abscess is caused by Entamoeba histolytica. Norflox TZ is prescribed to treat the condition.
  • Trichomoniasis: The tablet is used in the treatment of trichomoniasis. It is a sexually transmitted disease and is caused by Trichomonas vaginalis.
  • Gastrointestinal infections: These infections occur due to parasites or bacteria which result in inflammations in the gastrointestinal tract. The gastrointestinal tract includes intestine and stomach. Norfloxacin is prescribed to patients showing symptoms of gastrointestinal infections; such as vomiting, abdominal pain, diarrhea, etc.
  • Sexually Transmitted Diseases: The infection occurs due to bacteria and parasites. The infection is transmitted through sexual contact.

These are some of the major issues where Norflox is found to be effective; however, it is not an exclusive list. Also, some of the above conditions may occur due to viral infections as well, and in that case use of Norflox TZ is not recommended.


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Side Effects of Norflox TZ:

Apart from the intended effects, Norflox TZ tends to show certain undesired effects as well. These side effects may or may not be serious, but it is advised that patients inform the doctors when such side effects are experienced.

Some of the undesired effects which have been reported by the patients include the following:

  • Abdominal swellings
  • Abnormal blood count
  • Anal or rectal pain
  • Blurred vision
  • Breathing difficulty
  • Body ache
  • Constipation
  • Cough
  • Chills
  • Change in taste
  • Dizziness
  • Dry mouth
  • Sour stomach
  • Weakness
  • Gas
  • Headache
  • Indigestion
  • Loss of appetite
  • Nausea
  • Tendon rupture
  • Vomiting
  • Abdominal cramps
  • Itching
  • Mouth ulcer or Myasthenia gravis
  • Mood swings


The above-mentioned list is not an exclusive list; any discomfort experienced after consuming Norflox TZ should be brought to the attention of the doctor.


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Common Dosage of Norflox TZ:

The dosage is prescribed on the basis of the severity of the infection, age, gender and other clinical conditions. It is advised to share all the medical details with the medical practitioner before using Norflox TZ. Usually, the recommended dosage of Norflox is 1 tablet per 12 hours. In the case of children, Norflox TZ should be administered only after consulting a medical practitioner.
The course of Norflox TZ should be completed even if an individual experiences improvement in the health condition after first few doses. Not completing the course of Norflox TZ may result into development of drug-resistant bacteria. If Norflox TZ is being consumed as an over the counter medicine, then all the directions should be read carefully before the consumption of Norflox. In the case of a missed dose, Norflox should be taken as soon as possible. However, if it is time for the next dose then the usual schedule should be followed and in no case one should overdose on the Norflox TZ. In case an overdose is suspected, it is advised to seek medical help as soon as possible.


Composition and Nature of Norflox TZ:

Norflox TZ consists of the following two main ingredients:

Norfloxacin 400 mg: It is a synthetic antibacterial agent which belongs to the class of fluoroquinolone antibiotics. Norflox TZ is used to fight undesired bacteria in the body. The drug is found to be effective in the treatment of bacterial infections of the prostate, urinary tract, etc. 

Tinidazole 600 mg: The drug belongs to the category of antibiotics. The drug works by inhibiting the growth of bacteria and parasites. Hence, it is found to be effective in the treatment of trichomoniasis, vaginosis, parasite infections such as amoebiasis and giardiasis. 

Lactobacillus (120 million cells) is another salt used in this medicine and it belongs to the category of the bacterium. It helps in breakdown of food. Norflox TZ is prescribed to patients suffering from diarrhea, as lactobacillus assists in the absorption of nutrients from the food.


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How Norflox TZ Tablet Works?

The ingredients Norfloxacin and Tinidazole belong to the class of Fluoroquinolone antibiotics; they stop the DNA synthesis of the bacteria and ultimately kill the bacteria. The ingredients present in Norflox TZ work together to prevent growth of the bacteria in the body.

Lactobacillus in Norflox TZ restores the balance of good bacteria that gets disturbed either due to the infection of the intestine or use antibiotic medicines.


How to take the Norflox TZ Tablet?

  • The Norflox TZ tablet should be administered orally.
  • Norflox TZ should be swallowed whole and should not be chewed, broken or crushed before the consumption.
  • It is advised to take Norflox TZ on an empty stomach or 2 hours before the meal.
  • For best results, Norflox TZ should be taken at regular intervals to maintain a certain amount of drugs in the body.
  • Discontinuing the course of Norflox TZ may increase the risk of development of drug-resistant bacteria, thereby rendering the drug inefficient.


When is Norflox TZ Tablet prescribed?

Norflox TZ is prescribed in the following conditions:

  • Anemia
  • Nose infection
  • Bacterial infections
  • Stomach infection
  • Chest infections
  • Diarrhea
  • Ear infection
  • Eye infection
  • Lung infection
  • Sinusitis
  • Prostate infection
  • Parasitic infections
  • Sexually transmitted diseases
  • Skin infections
  • Intestinal infections
  • Infections in blood
  • Urinary tract infections
  • Sexually transmitted diseases
  • Reproductive organ infection
  • Lungs infection


The list is not an exclusive and the medicine might be used for conditions other than the ones mentioned above. A medical practitioner should be consulted before using Norflox TZ as there are some parasitic infections as well. 


Precautions and Warnings: When to avoid Norflox TZ?

The person suffering from any of the below mentioned conditions must not use the Norflox TZ tablet. The conditions are:

  • Any clinical condition such as seizure, muscle weakness, liver diseases, kidney diseases and heart diseases should be informed well in advance to the medical practitioner.
  • Patients with a medical history of tendon rupture are advised to avoid Norflox TZ.
  • Patients with history of allergy to Norflox TZ or any of its ingredients should inform to a doctor at the time of prescribing Norflox TZ.
  • In case Norflox TZ is to be administered in children; a doctor should be consulted in advance.
  • Norflox TZ should be avoided by pregnant women in their 2nd and 3rd trimester.
  • Ongoing medications should be shared with a medical practitioner in advance.
  • Norflox TZ should be avoided by lactating women as it can pose a severe risk to the baby.
  • Use of alcohol along with Norflox TZ may result in symptoms such as rapid heartbeat, low blood pressure, nausea, etc.
  • Exposure to sunlight or ultraviolet rays should be avoided.
  • It is advised not to operate heavy machinery or drive after consuming Norflox TZ.


Norflox TZ Substitutes:

Medicines that have the same composition, nature and course of action can be used as a substitute of Norflox TZ. Some of the most common substitutes are mentioned below:

S.No.Name of the MedicineManufacturing Company
1. AlfloxAlkem Laboratories Ltd. 
2. Alflox DpsAlkem Laboratories Ltd.
3.BacigylAristo Pharmaceuticals Ltd
4.BiofloxinBiochem Pharmaceutical Industries Ltd
5.EnterofloxDey’s Medical Stores (Mfg) Ltd
6.FloxLark Laboratories (I) Ltd
7. GyraxKlar Sehen Pvt. Ltd
8.HarfloxTaurus Laboratories Pvt. Ltd.
9.Harflox DpsTaurus Laboratories Pvt. Ltd.
10. NoriletDr. Reddys Laboratories Ltd.
11.LoxoneMicro Labs Ltd. 
12.UrofloxTorrent Pharmaceuticals Ltd. 


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Norflox TZ Interactions:

Norflox TZ when taken along with some other medicines, specific food items, etc. may result in several types of interactions including drugs interaction, lab interaction and disease interaction. 

Here is a list of interactions:

Drug interactions: Norflox TZ when taken along with other drugs can lead to neutralization of effect of either of the drugs. In some cases, it may result in undesired effect and worsening of the present clinical condition.

Hence, it is advised to inform the doctor about all the ongoing drugs including herbal and vitamin supplements.

Anti-coagulants: Anti-coagulant drugs are used for blood thinning. If an individual is using anti-coagulants, then a medical practitioner should be informed regarding the same.

Interaction of both the medicines may result in unwanted effects.

Birth control pills: If a woman is using contraceptive pills, then a medical practitioner should be informed regarding the same before Norflox TZ is prescribed. Use of birth control pill while using antibiotics may interfere with the effectiveness of the antibiotic.

Interaction of both medicines might lead to the reduced effectiveness of antibiotics.

Analgesics:These drugs are used as pain relievers. The drug should not be combined along with Norflox TZ, as Norflox TX reduces the metabolism of the analgesics.

Antipyretics: It is used for reducing fever and providing relief from pain. Drugs belonging to the category of antipyretics when combined with Norflox TZ lose their metabolism.

Hence, it is advisable to avoid the consumption of both at the same time.

Amantadine:Norflox TZ when combined along with Amantadine can increase the severity of QT prolongation. Hence, a doctor should be aware of Norflox TZ if it is in use.

Aluminum hydroxide:Drugs containing aluminum hydroxide as one of the salts when taken along with Norfloxacin decreases the absorption of Norfloxacin. Thus, the effectiveness of Norfloxacin is reduced.

Hence, it is advised to avoid the consumption of Norflox TZ.

Disease interactions: Norflox TZ when taken in case of a specific health condition may worsen the present clinical conditions. This may result in some other health conditions as well. Hence, it is advised to inform the medical condition.

Norflox TZ might interact with the following diseases:

Tendon rupture: The condition is also termed as Tendinitis. Use of Norflox TZ in this condition increases the risk of development of tendon rupture or tendinitis. This condition can affect hand, shoulder, ankle and other parts of the body.

The risk is higher in the case of people with age 60 years and above. People with a medical history of kidney, lung or heart transplant are susceptible to tendon rupture when on the course of Norflox TZ.

If symptoms of any such conditions are experienced, then it is advised to consult a doctor and seek medical assistance.

Central nervous system disorders: If an individual is suffering from CNS disorder, then the use of Norflox TZ should be avoided. It may result in hallucinations, anxiety, restlessness, tremors and confusions.

If any of the above mentioned side-effects are experienced, patients are advised to seek medical assistance as soon as possible. Also, it is advised to avoid the consumption of chocolates, energy drinks, coffee or any caffeine-containing product.

QT Prolongation: In case of any kind of chest discomfort, use of Norflox TZ should be avoided. Also, it is advisable to conduct cardiac functioning test if there is a medical history of heart diseases and Norflox TZ is being consumed.

Impaired liver: In case of a patient with a medical history or present condition of liver impairment, use of Norflox TZ should be strictly avoided. Use of Norflox TZ poses a severe risk of liver enzymes.

Colitis: If an individual experiences conditions such as diarrhea, blood in stools, abdominal pain, etc. after consumption of Norflox TZ, then its use should be strictly avoided.

Also, in case of gastrointestinal concerns, it is advised to inform a medical practitioner in advance before starting the course of Norflox TZ. It is advised to drink plenty of water to avoid dehydration.

Alcohol: Use of alcohol should be avoided while using Norflox TZ as it may result in worsening of the present medical condition. Also, it may cause drowsiness, sleepiness and dizziness.

Food interactions: It is advised to avoid the use of Dairy products as it may lead to certain undesired effects. To avoid any such interaction, it is advised to keep a gap of 2 hours between consumption of dairy products and Norflox TZ.


Medicines to be avoided while consuming Norflox TZ:

Here is a list of medicines that should be avoided while consuming Norflox TZ:

  • Acetaminophen
  • Caffeine
  • Cetirizine
  • Ascorbic acid
  • Ciprofloxacin
  • Warfarin
  • Omeprazole
  • Clozapine
  • Montelukast
  • Pyridoxine
  • Cholecalciferol
  • Cyclosporine
  • Dexamethasone
  • Glyburide
  • Hydroxychloroquine
  • Eszopiclone
  • Methylprednisolone
  • Tizanidine
  • Metoprolol
  • Montelukast
  • Nystatin
  • Omeprazole
  • Prednisone
  • Pregabalin
  • Probenecid
  • Pyridoxine
  • Ropinirole
  • Saxagliptin
  • Tacrine
  • Theophylline
  • Thyroid desiccated
  • Ubiquinone


Variants of Norflox TZ:

Norflox TZ is available in the following variations:

Medicine Composition
Norflox 400 tablet/ Norflox Lb- Norfloxacin 400
Norflox Oz Lb tablet- Ornidazole (500 mg) + Norfloxacin (400 mg) +Lactobacillus (NA)
Norflox Lb 200 mg Tablet- Norfloxacin (200 mg)
Norflox 100 mg Tablet Dt- Norfloxacin 100 mg
Norflox 0.30 % Eye/ Ear drops- Norfloxacin (0.30 %)


Norflox TZ Price in India

Norflox TZ INR 66.75/ 10 Tablets


Know the Storage of Norflox TZ Tablet:

  • Norflox TZ should be stored at room temperature.
  • Norflox TZ should be kept in an airtight container.
  • It should not be exposed to direct heat and light.
  • Norflox TZ should be kept away from the reach of children and pets.
  • It is advised not to flush or pour Norflox TZ in the drain. Doing so can result in environmental pollution.
  • If Norflox TZ has expired, then it should be disposed properly. A pharmacist should be consulted regarding the disposal instructions.



When should Norflox TZ Tablet be avoided?

Norflox TZ should be avoided in the following conditions:

Allergy: If an individual is allergic to any of the ingredients of Norflox TZ, it is advisable to avoid medicine.

Myasthenia gravis: Individuals with a history or family history of weakness and rapid fatigue of muscles under voluntary control should avoid Norflox TZ.

Diabetic patients: Any patient with a trace of diabetes should avoid the use of Norflox TZ. A doctor should be informed about the condition in advance.

Heart diseases: Patients with an existing or past medical condition of the heart should avoid the use of Norflox TZ. Patients should inform the doctor about their condition well in advance.


Norflox TZ  Tablet  FAQs:


1) Is Norflox TZ addictive in nature?

Ans: In case of Norflox TZ, no such tendency has been reported yet. Addictive or controlled substances are categorized under II-IV schedule by the government. Individuals should look for nay such category on the packaging.


2) Can a person drive after taking Norflox TZ Tablet?

Ans: No, it is not safe to drive a vehicle after consuming this Norflox; as Norflox is known to cause drowsiness and dizziness upon consumption.


3) Is the use of Norflox TZ tablet safe during Pregnancy or Breastfeeding?

Ans: No, use of Norflox TZ is not safe for breastfeeding women as it poses a severe risk to the newborn child.


4) Can one have alcohol with Norflox TZ?

Ans: No, it is not suggested to consume Norflox TZ along with alcohol. The alcohol interaction increases the health risk and may lead to adverse side effects.


5) What if a dose of Norflox TZ is missed?

Ans: If by chance a dose is missed, it is advisable to consume Norflox TZ as soon as possible. But if it is time for the next dose, the missed dose can be skipped for the next scheduled dose. It is advised not to take multiple doses.


6) Can one use Norflox TZ to treat the common cold?

Ans: No, Norflox TZ tablet is not recommended to be consumed for the treatment of viral infections such as common cold. Norflox TZ tablet is effective for bacterial infection and should be strictly avoided for viral infections.


7) Can Norflox TZ tablet be used to treat stomach infection?

Ans: Yes, it can be used to treat stomach infections. The lactobacillus in Norflox TZ tablet also helps to treat diarrhea and indigestion to a great extent.


8) Is the use of Norflox TZ Tablet safe during Pregnancy?

The consumption of Norflox TZ Tablet should be avoided in case of pregnant women, specifically in their 2nd and 3rd trimester. In case of emergency, a doctor should be consulted for a suitable alternative to Norflox TZ.


9) Are there any special tips to keep in mind while using the Norflox TZ tablet?

An individual who is consuming Norflox TZ tablet may find needle-shaped crystals in the urine. This happens due to an overdose of Norflox TZ. It is advisable to drink plenty of water to avoid such conditions.


10) Is it safe to discontinue the course of Norflox TZ tablet if the symptoms improve?

No, even if the symptoms disappear, a full course of the Norflox TZ tablet should be completed. Not doing so might lead to worsening of the present condition and high risk of growth of drug-resistant bacteria.


11) Is the Norflox TZ Tablet banned in India?

No, the Norflox TZ tablet is not banned in India. It is easily available in the drug store.


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Last updated on : 25-02-2019

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