Oflox OZ Tablet: Uses, Side Effects, Composition & Dosages

Oflox OZ is a fluoroquinolone antibiotic medicine which is used to treat common infectious diseases like pneumonia, chronic bronchitis, gonorrhea, plague, anthrax, gingivitis, pelvic inflammatory disease etc.

Nature of Oflox OZ: Antibiotic
Composition of Oflox OZ: Ofloxacin (200mg) + Ornidazole (500mg)
Uses of Oflox OZ: Urinary tract infection, ear infection, gonorrhea, and skin infections.
Side effects of Oflox OZ: Nausea, loss of appetite, dizziness, headache, allergic skin reaction, abdominal pain.
Precautions of Oflox OZ: People with epilepsy, multiple sclerosis, myasthenia gravis, and hypersensitivity should avoid this medicine.
Oflox OZ Tablet

This antibiotic drug works by inhibiting the production of certain enzymes in the bacteria that are responsible for cell growth. This prevents the infection from growing, thereby curing the symptoms associated with the condition. Oflox OZ is manufactured in India by Cipla Ltd.

Uses and Benefits of Oflox OZ:

Oflox OZ is an anti-bacterial medicine which is majorly used to cure mild to severe bacterial infections. Oflox OZ also treats the following health conditions and infections:

  • Throat infection
  • Stomach infection
  • Infection in the Urinary Tract
  • Vaginal Infection
  • Skin Infection
  • Nose Infection
  • Ear Infection
  • Infections of the genitals in female
  • Infection of the soft tissue
  • Lung Infection
  • Gonorrhea
  • Bronchitis
  • Hearing loss
  • Ringing in ears
  • Protozoan infections
  • Respiratory infections
  • Sexually transmitted diseases
  • Tuberculosis
  • Typhoid fever
  • Urinary tract infections
  • Discharge from the Urethra or Vagina
  • Bacterial infections by inflammation of the peritoneum
  • Periodontitis
  • Diarrhea
  • Dysentery
  • Gingivitis
  • Pelvic inflammatory disease

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Side Effects of Oflox OZ:

Apart from the intended effects of the medicine, some medicines may result in side effects when consumed. Oflox OZ is no exception. Consumption of Oflox OZ tablet may result in side effects that may or may not be life threatening; however, it is important to consult a doctor when an adverse effect is experienced. Some of the commonly reported side effects of Oflox OZ are mentioned below:

  • Nausea
  • Vomiting
  • Allergic skin reaction
  • Abdominal pain
  • Exhaustion
  • Sleepiness
  • Numbness
  • Tremors
  • Diarrhea
  • Headache
  • Dizziness
  • Insomnia
  • Hallucinations
  • Leucopenia and Eosinophilia
  • Vaginitis
  • Dysgeusia
  • Tendon damage and rupture
  • Anorexia
  • Photosensitivity
  • Hypersensitivity reactions
  • Seizures
  • Anaphylaxis
  • Neurological reactions
  • Abnormal taste
  • Vertigo
  • Fits
  • Loss of appetite

Some people may face serious side effects of Oflox Oz-like brain disorders, kidney problems, tendonitis, myasthenia gravis, epilepsy, bone disorders etc. In such conditions, it is advisable to contact the doctor immediately.

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Common Dosage of Oflox OZ:

This medicine is available in the form of tablets. The dosage of Oflox OZ depends on the health condition, age, gender, weight and medical history of the patient. Strict guidelines of the doctor are advised to be followed by the patients while consuming these tablets. The tablet should be swallowed whole without crushing, chewing or breaking.

  • Missed Dose : A missed dose of Oflox OZ must be taken as soon as it is remembered. If the missed dose is remembered when it is almost time for the next dose, then the missed dose should be skipped and the next scheduled dose should be consumed. Patients should not take an extra dose in order to make up for the missed dose.
  • Overdose : In case of suspicion of an overdose, it is advised to seek immediate medical attention in order to avoid any adverse effects.

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Composition and Nature of Oflox OZ:

Oflox OZ tablets are antibiotic in nature. Oflox OZ tablet consists of the following active ingredients:

  • Ofloxacin (200mg) : This active ingredient works by preventing the bacterial cells from dividing, thereby killing the bacteria.
  • Ornidazole (500mg) : This ingredient inhibits the growth of parasites and anaerobic bacteria that cause infections.

Read More: Aspirin Composition | Cefixime Composition

Oflox OZ Tablet Price in India

Name Price
Oflox OZ Tablet (Strip of 10 Tablets) INR 136.40/-

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When is Oflox OZ Prescribed?

Oflox OZ is an antibiotic medicine which is prescribed to cure parasitic and bacterial infections. It is also used to cure gastrointestinal infections such as acute diarrhea, dysentery, gynecological infections, lung infections, and urinary infections. Oflox OZ works by inhibiting the growth of microorganisms which kill the infection-causing bacteria. As a combination medicine, Oflox OZ tablet is also prescribed for the treatment of diarrhea of mixed infection in case of adult patients only. This medicine is not recommended to be consumed by patients less than 18 years of age.

How to Use Oflox OZ ?

It is advised to follow the directions written on the package of the medicine or as advised by the doctor. The tablet must be swallowed whole, without crushing or breaking or chewing. For better absorption, it is suggested to take Oflox OZ tablet with food. Taking the medicine on an empty stomach can result in problems in the stomach.

How does Oflox OZ Tablet work?

Oflox OZ tablet is a combination drug consisting of the two active ingredients –

  • Ofloxacin
  • Ornidazole

Ofloxacin tablet helps kill the bacteria by preventing the bacterial cells from dividing and multiplying. Ornidazole kills parasites and anaerobic bacteria that cause infections by damaging their DNA. Together, the infection is treated effectively.

Warnings/Precautions: When to avoid Oflox OZ Tablet:

A few health conditions which affect the administration and effects of Oflox OZ are:

  • Alcohol: Symptoms like flushing, increased heartbeat, nausea, thirst, chest pain, and low blood pressure are commonly observed when alcohol is taken with Oflox OZ.
  • Pregnancy and Breastfeeding: Oflox OZ tablet may be unsafe for pregnant females and hence it is advised to consult the doctor before administering the medicine. In the case of lactating mothers, there is no medical information available for the use of Oflox OZ tablet and hence consultation with the doctor is necessary.
  • Kidney and Liver-Related Problems: Oflox OZ is safe to be consumed by people suffering from kidney related problems. In the case of patients suffering from liver-related disorders, it is advised to use the medicine with caution. It is advised to consult the doctor before administering Oflox OZ.
  • Driving and Operating Heavy Machinery: Oflox OZ can cause dizziness and blurred vision, and hence driving should be avoided and heavy machinery should not be operated after consuming this medicine.
  • Allergic Reactions: If a person is allergic to the ingredients of Oflox OZ, then they are advised to avoid using the medicine.

Health conditions under which administration of Oflox OZ is advised only after doctor’s consultation are:

  • Epilepsy
  • Multiple Sclerosis
  • Myasthenia Gravis
  • Hypersensitivity

Oflox OZ Tablet Substitutes:

Medicines with the same composition and nature can be used as substitutes of Oflox OZ tablet. The following substitutes of Oflox OZ tablet can be used as alternatives of this medicine:

  • Tobradex tablet manufactured by Novartis Pharmaceuticals Corporation
  • Vigamox tablet manufactured by Alcon Laboratories Inc.
  • Besivance manufactured by Bausch and Lomb Inc.
  • Loobid tablet manufactured by Cachet Pharmaceuticals Pvt. Ltd.
  • O2 tablet manufactured by Medley Pharmaceuticals
  • Ornof tablet manufactured by Aristo Pharmaceuticals Pvt. Ltd.
  • Brakke tablet manufactured by Franco-Indian Pharmaceuticals Pvt. Ltd.
  • Zanocin OZ tablet manufactured by Sun Pharmaceutical Industries Ltd.
  • Oflomac OZ tablet manufactured by Macleods Pharmaceuticals Pvt. Ltd.
  • Nor-Metrogyl Plus tablet manufactured by Lekar Pharma Ltd.
  • Orni-O tablet manufactured by Zydus Cadila
  • Zil-O tablet manufactured by Abbott
  • Ordent tablet manufactured by Dr. Reddy’s Laboratories Ltd.
  • Oflotas OZ tablet manufactured by Intas Pharmaceuticals Ltd.
  • Saril tablet manufactured by Shreya Life Sciences Pvt. Ltd.
  • Ornamac tablet manufactured by Macleods Pharmaceuticals Pvt. Ltd.
  • Zorno tablet manufactured by FDC Ltd.
  • Oson O tablet manufactured by Unison Pharmaceuticals Pvt. Ltd.
  • Normet tablet manufactured by Zuventus Healthcare Ltd.
  • Mahacef OZ tablet manufactured by Mankind Pharma Ltd.

Oflox OZ Tablet Interactions:

Medicines when combined with certain drugs, food items, and beverages, or when taken in case of pre-existing health conditions, can lead to interactions. These interactions can alter the effects of the medicine or worsen the conditions of the patients.

Interaction with drugs

Oflox OZ when combined with the following medicines may result in drug-to-drug interaction.

  • Acetaminophen
  • Amiodarone
  • Anisindione
  • Bupropion
  • Metrizamide
  • Mifepristone
  • Saquinavir
  • Vecuronium
  • Warfarin
  • Anti-psychotics
  • Azithromycin
  • Disopyramide
  • Dofetilide
  • Hydroquinidine
  • Ibutilide
  • Quinidine
  • Sotalol
  • Tricyclic Anti-Depressants

Interaction with Diseases

Effects of Oflox OZ tablet in the following health conditions vary depending on the person’s age, weight, gender, and other factors. It is advised to consult the doctor before administering Oflox OZ in the following health conditions:

  • Central Nervous System Disorders : Patients with a history of seizure disorder and other abnormalities of the central nervous system are advised to use Oflox OZ with extreme caution to avoid further complications. Tremors, restlessness, anxiety, confusion, hallucinations etc. should be reported to the doctor immediately to adjust the dose or suggest an alternative.
  • Gastrointestinal Diseases : Patients with a history of gastrointestinal diseases, particularly colitis, are advised to inform the doctor about their condition. Oflox OZ is administered with extreme caution in such patients to avoid further complications. Incidences of severe diarrhea, abdominal pain, blood in stools etc. are to be reported to the doctor immediately to make necessary adjustments in the medicine dose as may be required.
  • QT Prolongation : Risks of health complications are higher in patients with a history of QT prolongation, heart diseases, and electrolyte disbalance, especially in elderly patients. In case of discomfort in the chest, heart palpitations, etc. the doctor should be informed on priority. The doctor may monitor the functioning of the heart and vital signs closely and suggest appropriate dose adjustment or replacement.
  • Kidney Disease : Patients with kidney related disorders are at an increased risk of serious side effects of Oflox OZ tablet. Doctor will closely monitor the kidney function during the entire course of this medicine. Doctors will make the necessary dose adjustment and prescribed suitable alternative to this medicine.

Interaction with Alcohol

Consumption of alcohol is not recommended during the administration of Oflox OZ as it may affect mental alertness and interfere with activities like driving and operation of heavy machinery.

Medicines not to be taken with Oflox OZ:

The following medicines are not advised to be taken with Oflox OZ:

  • Acetaminophen
  • Amiodarone
  • Anisindione
  • Bupropion
  • Metrizamide
  • Mifepristone
  • Saquinavir
  • Vecuronium
  • Warfarin
  • Anti-psychotics
  • Azithromycin
  • Disopyramide
  • Dofetilide
  • Hydroquinidine
  • Ibutilide
  • Quinidine
  • Sotalol
  • Tricyclic Anti-Depressants

Oflox OZ Variant:

  • Oflox OZ 200mg/500mg Infusion (bottle of 100ml infusion)
  • Oflox OZ Suspension (bottle of 30ml suspension)

Oflox OZ Suspension Form:

  • Oflox OZ Suspension (bottle of 30ml suspension)

Oflox OZ Storage:

In order to store Oflox OZ and ensure its efficacy, it is advised to store the medicine in the container or pack it came in and keep the same tightly closed. Store the medicine according to the instructions given on the pack or label of the medicine.

  • It is advised to store Oflox OZ at room temperature, away from direct sunlight and heat. The ideal temperature for storing Oflox OZ is below 25 degrees Celsius.
  • Keep Oflox OZ away from children and pets.
  • Do not use Oflox OZ after the expiry date mentioned on the label.

Oflox OZ Tablet FAQs:

1) Can Oflox OZ tablet be used in treating inflammation of the peritoneum?

Ans: Yes, Oflox OZ tablet is very useful in treating this condition. However, it is advised to administer the dose only after doctor’s consultation.

2) What are the special dietary instructions during the administration of Oflox OZ tablet?

Ans: It is advised to avoid the consumption of milk and dairy products during the administration of Oflox OZ.

3) Can Oflox OZ tablet be used to treat viral infections?

Ans: No, Oflox OZ tablet can only be consumed to treat bacterial infections. It is advised to consult the doctor for appropriate medicine in case of any viral infections.

4) Is Oflox OZ tablet habit forming?

Ans: Oflox OZ tablet is not categorized under the schedule H or X and hence it is not a habit-forming medicine.

5) Is it safe to consume alcohol with Oflox OZ tablet?

Ans: No, alcohol is not advised to be consumed during the course of Oflox OZ tablet. The interaction of medicine with alcohol may increase the side effects or cause low blood pressure or excessive drowsiness.

6) What is the onset of action of Oflox OZ tablet?

Ans: The effects of Oflox OZ tablet are visible within one to three hours of administration of the dose.

7) What is the duration of effect of Oflox OZ tablet?

Ans: The effect of the medicine lasts for an average duration of 24 hours.

8) Can I take higher than the recommended dose of Oflox OZ tablet?

Ans: No, taking a higher than the prescribed dose of Oflox OZ tablet increases the risk of side effects. Increased severity of the symptoms which are not relieved by the recommended dose should be brought to the notice of the doctor.

9) Can Oflox OZ tablet be stopped once symptoms are relieved?

Ans: No, it is advised to continue Oflox OZ tablet even after the symptoms are relieved. One should consult the doctor regarding the continuation of the medicine once symptoms are cured.

10) Can Oflox OZ tablet increase the risk of tendinitis or tendon rupture?

Ans: Yes, use of Oflox OZ may increase the risk of developing tendinitis or tendon rupture during the administration of the medicine or even after months of consumption. The condition affects the shoulders, hands, ankles, or other parts of the body. Elderly patients are at a higher risk, as well as patients having undergone kidney, heart or lung transplant. People on corticosteroids like dexamethasone, methylprednisolone, or prednisone should report any unusual symptoms to the doctor.

11) Can Oflox OZ tablet be administered to people suffering from multiple sclerosis?

Ans: Multiple sclerosis is a neuro-degenerative disorder of the brain. The medicine should be used with extreme caution in patients suffering from this condition. Based on the doctor’s prescription, appropriate dose adjustment or replacement with a suitable alternative may be necessary based on the clinical condition.

12) What effects does Oflox OZ tablet have in patients with photosensitivity?

Ans: The medicine makes a person more sensitive to sunlight or tanning. It is advised to use sunscreen and wear protective clothing to avoid adverse reactions from the sunlight during the administration of this medicine.

13) What are the specific contraindications associated with Oflox OZ tablet?

Ans: The use of Oflox OZ is considered to be harmful in patients with the following health conditions:

Known allergy to Ofloxacin or to Ornidazole or any medicine which belongs to the quinolone or nitroimidazole group of antimicrobial agents.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

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