Pantosec D SR Capsule: Uses, Side Effects, Composition, Price & Dosages

Pantosec D SR is manufactured and marketed by Cipla Limited. It belongs to the family of dopamine antagonists. It is associated with the treatment of gastrointestinal disorders like acidity, flatulence, ulcers, nausea, and vomiting. It comes in the form of capsules, tablets and injections.

Nature of Pantosec D SR Capsule: Dopamine Antagonist
Uses of Pantosec D SR Capsule: Excessive acid secretion in the stomach, Intestinal ulcers, Acid reflux, Heartburn, Intractable nausea and vomiting, Bloating,
Inflammation of the oesophagus, Treatment for symptoms associated with diabetic and idiopathic gastroparesis
Composition of Pantosec D SR Capsule: Domperidone and Pantoprazole
Side Effects of Pantosec D SR Capsule: Diarrhoea, Abdominal pain, Flatulence, Dizziness, Rashes, Dry Mouth, Headache, Skin rashes, Increased chances of fractures
Precautions: Hypersensitivity, Kidney and liver diseases, blockage in the intestine, Electrolyte disturbance, Congestive heart failure, Osteoporosis
Pantosec D SR Capsule

The drug acts on the upper digestive tract, aiding the food to move quickly through the digestive system and thereby suppressing symptoms of nausea, vomiting and bloating.

Uses and Benefits of Pantosec D SR:

Pantosec D SR Capsule sustained-release capsule/tablet is used to provide relief from gastrointestinal disturbances. Use of Pantosec D SR is recommended for treatment of intestinal or stomach ulcers, flatulence, acidity and extreme nausea or vomiting. A few other uses of Pantosec D SR are:

  • Pantosec D SR is used in the treatment of Erosive Esophagitis. It neutralizes excessive acid which is responsible for ulceration and inflammation of the oesophagus.
  • It is prescribed for the treatment of Gastroesophageal Reflux Disease.
  • Pantosec D SR is also prescribed to alleviate gastric symptoms related to idiopathic or diabetic gastroparesis.
  • Pantosec D SR is effective in controlling extreme nausea and vomiting.
  • It provides relief from discomfort associated with flatulence and belch.
  • It provides symptomatic relief in gastric disorders due to Zollinger-Ellison Syndrome and similar hypersecretory conditions.
  • Pantosec D SR eases the symptoms arising from gastric mobility disorders.

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Side Effects of Pantosec D SR:

Apart from the intended effects of the medicines, they are bound to show some side effects in some cases. These side effects may or may not be life-threatening, but in case patients experience side effects after consuming the medicine, they should seek immediate medical attention. Some of the side effects are mentioned below:

  • Skin rash , pruritus, and itching
  • Myxedema or swelling of face, eyelids, tongue and rarely of extremities.
  • Breathlessness and chest pain
  • Dizziness and convulsions
  • Hot flushes and change of menstrual cycle
  • Increased thirst and dry mouth
  • Tachycardia or bradycardia
  • Painful and tender breasts
  • Galactorrhoea or abnormal breast milk production without stimulation
  • Gynecomastia or breast development in men
  • Low libido
  • Diarrhoea or constipation
  • Conjunctivitis and blurred vision

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Common Dosage of Pantosec D SR:

Pantosec D SR Capsule dosage is determined by the physician on the basis of type and intensity of disorder that an individual is suffering from. The general oral Pantosec D SR dosage for adults is 1 capsule daily. It is not recommended for children below 2 years or weighing less than 35 kg.

  • Missed Dosage: Take the missed dose as soon as it is remembered. However, it is recommended not to take the missed dose if it is almost the time for the next dose.
  • Over Dosage : Over dosage of Pantosec D SR may result in serious side effects. Rush immediately to a doctor, if over dosage is suspected. Increased heartbeat, tremors, confusion and drowsiness are a few symptoms of over dosage.

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Composition & Nature of Pantosec D SR:

Pantosec D SR Capsule is a dopamine antagonist drug. Each capsule is composed of the following active ingredients:

  • Domperidone-30 mg: It is a dopamine D2 receptor antagonist which works without the involvement of the Central Nervous System. It is a derivative of Benzimidazole and has a similar molecular structure as that of antipsychotic drugs like Haloperidol.
  • Pantoprazole-40 mg: Pantoprazole is a proton pump inhibitor. It is a lipophilic weak base which neutralizes excessive acid. Chemically, pantoprazole is a substituted Benzimidazole.

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Pantosec D SR Price in India:

  • Pantosec D SR Capsule (10 Capsules):  INR 114

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When Pantosec D SR is Prescribed?

Pantosec D SR Capsule is classified as a Dopamine Antagonist and is used to treat stomach or intestinal ulcers, excess acid in the stomach, acid reflux, and intractable nausea and vomiting. Doctors may also prescribe this medicine to cure a few other conditions, such as inflammation in the oesophagus, difficulty in swallowing and heavy bloating.

How to use Pantosec D SR Capsule?

Follow the directions as directed by the doctor or as prescribed on the label. Do not increase or decrease the dosage without consulting the doctor. Swallow it as a whole. Do not chew, crush or break it. Usually, this medicine is taken half an hour before food.

How Does Pantosec D SR Work?

Pantosec D SR 30/40 mg capsule/tablet works by blocking the dopamine receptors. This action decreases the production of acid in the stomach.

  • Domperidone: Domperidone facilitates faster movement of food through the oesophagus. This prevents backflow and doesn’t allow the food to stay in the same place for a prolonged duration. It exerts gastrokinetic effects and blocks Dopamine receptors. By doing so, the sensation of nausea and sickness is blocked.
  • Pantoprazole: It is a proton pump inhibitor. Pantoprazole inhibits gastric acid production by binding covalently to the H+/K+ ATP pump on gastric parietal cells in the stomach. The binding doesn’t allow gastric acid production for a period of up to 24 hours.

Warnings/Precautions- When to avoid Pantosec D SR Capsule?

While consuming Pantosec D SR Capsule, following points must be kept in mind:

  • Hypersensitivity: Pantosec D SR is not recommended for patients with any kind of allergy to Dopamine Antagonist. Avoid the usage of the drug if the patient has a hypersensitivity to Domperidone or Pantoprazole.
  • Kidney Disease: Pantosec D SR shows severe side effects in patients with an impaired kidney. It should be used with extra care and caution in patients having a known history of kidney related disorder. Appropriate adjustment to the dose and close monitoring of kidney function are required in such cases.
  • Liver Disease: Pantosec D SR shows adverse effects in the patients with any liver-related disorder. It should be used with extra care and caution in patients having a known history of liver disease. Appropriate adjustment to the dose and close monitoring of liver function parameters are required in such cases.
  • Pregnancy: Use of this medicine in pregnant women should be avoided unless potential benefits outweigh the risks.
  • Breastfeeding: This medicine should be avoided by the ladies during their lactation period as it may mix with blood thereby can harm the infant.

A few other points that should be considered are:

  • Prolonged use of Pantosec D SR may lead to bacterial overgrowth in the gastrointestinal tract.
  • Consumption of alcohol during Pantosec D SR treatment may increase stomach acid leading to severe side effects.

Substitutes for Pantosec D SR:

Following drugs can be used as for Pantosec D SR:

  • Pantakind-DSR Capsule from Mankind Pharma Limited.
  • Pantodac DSR Capsule by Zydus Cadila.
  • Jopan DSR capsule by Dr Johns Labs.
  • Nupenta DSR capsule from Macleods Pharmaceuticals Private Limited.
  • Pantofer DSR Tablet by Biophar Lifesciences.

Pantosec D SR Capsule Interactions:

Interaction with drugs:

Using Pantosec D SR in combination with other over the counter medicines, herbal medicines and vitamin supplements can increase the risk of side effects. Pantosec D SR is known to negatively interact with the following drugs:

  • Amiodarone
  • Amprenavir
  • Atazanavir
  • Atropine
  • Antacids
  • Aprepitant
  • Clarithromycin
  • Fluconazole
  • Diltiazem
  • Erlotinib
  • Fosamprenavir
  • Erythromycin

interactions with Disease:

If an individual is suffering from any of the below-mentioned health condition, it is advised to consult a medical practitioner before using Pantosec D SR.

  • Pregnancy
  • Lactation
  • Renal Dysfunction
  • Liver Impairment

Interaction with alcohol:

Mixing alcohol with Pantosec D SR of alcohol may increase stomach acid leading to severe side effects. It is advised to avoid alcohol during the duration of the medicine.

Pantosec D SR Variants:

Variants of Pantosec are:

  • Pantosec D SR Capsules
  • Pantosec 40 mg Tablet
  • Pantosec D
  • Pantosec IV 40 mg Injection

Medicines that should not be taken with Pantosec D SR Capsule:

Mixing two or more medicines may change how the drug works and may increase the risk of side-effects. A few drugs that should not be taken with Pantosec D SR are:

  • Indinavir
  • Itraconazole
  • Itraconazole,
  • Ketoconazole
  • Voriconazole
  • Warfarin
  • Nefazodone
  • Nelfinavir
  • Ritonavir
  • Posaconazole
  • Methotrexate
  • Pantoprazole
  • Saquinavir
  • Telithromycin
  • Verapamil

How to Store Pantosec D SR?

It is advisable to store the medicine in a cool and dry place away from the reach of children and pets. The packaging of the medicine must be kept intact in order to maintain its effect when being administered.


1) How many minutes before a meal should I take Pantosec D SR Capsule?

Ans: Pantosec D SR should be taken 15-30 minutes before having a meal.

2) I am suffering from a cirrhotic liver. Is it safe for me to take Pantosec D SR when I get heartburn?

Ans: No, several adverse effects on the liver by Pantosec D SR Capsule SR has been reported. It is not advisable to use this medicine in case of any liver-related disorders. If you are experiencing heartburn, consult a doctor before taking any medicine.

3) Can I take Pantosec D SR Capsule with alcohol?

Ans: Combining Pantosec D SR with alcohol can cause adverse ill-effects. Thus, it is not advisable to combine Pantosec D SR with alcohol.

4) Is Pantosec D SR safe to consume by a pregnant woman?

Ans: It is always advisable for the expecting mothers to avoid the use of Pantosec D SR Capsule as the drug show adverse effect on the fetus. If it is necessary to use the medicine, consult a doctor first.

5) Is Pantosec D SR Capsule safe for lactating females?

Ans: It is always recommended for lactating mothers to avoid the use of Pantosec D SR as the drug may mix with blood and pass on to the baby. If it is necessary to use the medicine, consult a doctor first.

6) What is the normally recommended dosage of Pantosec D SR for an adult?

Ans: The normally prescribed dosage of Pantosec D SR Capsule for adults is 1 capsule daily. However, the dosage may vary from patient to patient on the basis of type and intensity of disorder that an individual is suffering from.

7) How does Pantosec D SR work?

Ans: Pantosec D SR is a dopamine antagonist that works by blocking the dopamine receptors to reduce to amount of acid production.  It mainly targets the production of the bad acid that travels up the stomach, causing, indigestion, heartburn, and gastro-oesophagal reflux or GERD.

8) What is Pantosec D SR used for?

Ans: Pantosec D SR Capsule is a dopamine antagonist that is used to treat intestinal or stomach ulcers, acid reflux and excessive acid secretion. In some cases, it may also be prescribed to provide relief in conditions like inflammation in the oesophagus, difficulty in swallowing and heavy bloating.

9)What are the optimal storage conditions of Pantosec D SR Capsule?

Ans: It should be stored at room temperature (15-30 degree Celsius), away from direct light and moisture.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

User Comments (1)


Rattan deep Singh

Thu Apr 18 2019

Hi there i am taking one capsule daily from last few years . I cant eat anything without eating pantosec Dsr .i suffer from gastric and heart burns if i dont take it . Is it safe to take it on daily basis . My doc said you have to eat it until u go through a surgery of hernia,


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