Primolut N Tablet: Uses, Side Effects and Dosage

Primolut N tablet is a synthetic form of progestin, and its function is similar to female hormone progesterone. This medicine is used to treat disorders related to menstruation and abnormal vaginal bleeding caused in women because of hormonal imbalance.

It is used as a form of birth control for preventing unwanted or unplanned pregnancies.

Primolut N Tablet

Composition and Nature of Primolut N Tablet:

Primolut N tables consist of an active ingredient, norethistherone, a synthetic composition of the female hormone, progesterone. Each tablet contains 5 milligrams of norethistherone.

Uses and Benefits of Primolut N Tablet:

Primolut N is used primarily used to treat abnormal vaginal bleeding and menstrual disorders. It is also used as a contraceptive emergency tablet.

Side Effects of Primolut N Tablet:

Some of the severe and rare side effects include:

  • Blurred vision or loss of vision
  • Blood particles in cough
  • Breathing difficulty
  • Yellowing of eyes and skin
  • Crushing or sharp chest pain
  • Swallowing difficulty

Other side effects include:

  • Breast enlargement
  • Irregular menstrual periods
  • Trouble with sleep
  • Facial hair growth
  • Depressed mood
  • Allergic skin reaction
  • Fainting and dizziness

Read More: Sinarest Side Effects | Stemetil Side Effects

Primolut N Dosage

The dosage must the followed as per the doctor's instructions and can vary. In case a dose is missed one must take the medicine as soon as one remembers.

However, in cases of overdose, contact the doctor right away. The symptoms of an overdose include vaginal bleeding, nausea, and vomiting etc.

How Primolut N Works:

Progesterone is responsible for the development of the lining of the womb or endometrium that is required for pregnancy. The body produces progesterone during the menstrual cycle causing the lining to be flushed out.

If a fertilized egg does not get attached to the womb's lining when the menstrual cycle ends it results in the progesterone level in the body to decrease. As a result, the body sheds this lining during the menstruation.

However, in the event that the egg gets fertilized then it gets attached to the womb lining during the end of the monthly cycle and the progesterone level in the body remains high. It also helps keep the womb healthy during pregnancy.

Norethistherone acts like progesterone and helps regulate the growth of the womb and the shedding of the womb lining. This synthetic compound helps treat menstrual disorders like painful periods, endometriosis, irregular period, and PMS.

Precautions and Warnings Related To Primolut N Tablet:

Pregnant and breast-feeding women are not recommended to take this medicine and must consult the doctor if consuming this medicine. Also, women who are planning for pregnancy in the foreseeable future must avoid use of this medicine.

Some general warnings that need to be kept in mind include:

  • Depression: The use of this medicine may cause varying levels of depression and must be carefully prescribed; if depressive episodes become severe or frequent discontinue taking the medicine.
  • Blood clotting disorder: The use of this medicine may cause thromboembolism i.e. blood clots in deep veins or arteries.
  • Fluid retention: The use of this medication may cause fluid retention and caution must be taken by those with a history of kidney impairment, migraine, asthma, and epilepsy.
  • Use in children: The medicine is not advised to be prescribed to women prior to menarche.
  • Smoking: Those with a history of smoking are advised to consult the doctor before taking this medication as it may have adverse effects on them.
  • Surgery: The use of this medicine must be stopped 4 days prior to planned surgery or immobilization that is prolonged.
  • Other medicines: The use of this medicine might lead to interactions with other medicines and hence a doctor must be consulted before taking it.

Substitutes of Primolut N Tablet:

Some of the substitutes for Primolut N include:

  • Covafem 5 mg tablet
  • Gynaset 5 mg tablet
  • Norgest 5 mg tablet
  • Regestrone 5 mg tablet
  • Norlut 5 mg tablet

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Drug interactions differ from one individual to the other. However, one must check possible interactions of Primolut N with a doctor before taking this medicine.

The interaction of this medicine with alcohol is unknown but it is advisable to consult the doctor before taking this medicine.

The medicine may also interact severely with the following medicines:

  • Mycophenolate Mofetil
  • Tranexamic Acid
  • Phenyotin
  • Griseofulvin
  • Carbamzepine
  • Phenobarbital

The medicine may interact moderately with the following medicines:

  • Insulin
  • Divalproex
  • Aminophyline
  • Clarinthromycin

When the medicine reacts with the disease Hepatic neoplasms it affects patients with liver tumours severely and hence individuals diagnosed with liver tumours need to exercise caution before taking this medication.

Frequently Asked Questions (FAQs):

1) Can Primolut N be consumed by a pregnant woman?

Ans: No, the medicine is not intended to be consumed by women who are pregnant

2) Can this medicine be consumed by breastfeeding mothers?

Ans: No, this medicine is not safe to be consumed by mothers who are breastfeeding.

3) Can this medicine be taken as a contraceptive and for heavy as well as irregular periods?

Ans: Yes, this medicine can be used as a contraceptive. It can also be used to treat painful, irregular, or heavy periods. However, before using this medication one must consult a doctor.

4) How long should the medicine be used before patients start to see improvements in their condition?

Ans: According to patients using this medication they have been able to see improvements on the day the medicine was taken or a day after consuming the medicine. However, patients are advised to meet the doctor and apprise them of how they are feeling to determine how long the medicine needs to be administered.

5) What is the frequency at which this medicine needs to be consumed?

Ans: According to users, the reported dosage ranges from once a day to three times a day. However, it is essential that patient's follow the doctor's advice on the dosage and frequency.

6) Should the tablet be consumed before or after meals?

Ans: According to users the tablet is consumed after meals by most. However, one should follow the instructions given by the doctor, especially the timing.

7) Is it safe to drive a vehicle or operate heavy machinery after taking the medicine?

Ans: Individuals who experience side effects like headaches, dizziness, drowsiness, or hypotension are advised not to operate heavy machinery or drive vehicles after taking the medicine. Also, patients are advised not to drink alcohol along with the medication as it can intensify the side-effects.

8) Can the consumption of the medicine be stopped immediately or should it be slowly weaned off?

Ans: Some medicines require to be tapered since they cannot be stopped immediately due to rebound effects. However, to be on the safe side one must consult the doctor before stopping medications.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

User Comments (4)



Sun Mar 31 2019

can this drug cause menstrual recycle, that is , if you are to see you period on the 18th - 03, can it change it to 10th- 04 ?



Wed Jul 03 2019

Can primolute n induce normal menstruation after two months of using contraceptive without menstruation



Fri Apr 05 2019

Can n tablet be taken after 5days of unprotected sex


Victoria Mgonja

Sat May 04 2019

I'm 31 years old for the past 6months I have been experiencing very severe abdominal pain during menstrual periods but the blood doesn't come out I used primolut n once and stopped and the following circle I was able to see little blood and the pain reduced for this month the problem is back again I have experienced very severe pain with no blood just spots of blood my question is should I use primolut n again and I'm expecting to be pregnant around August 2019



Tue Jun 18 2019

Can this drugs cause hot flushes?


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