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Prothiaden 25 MG Tablet: Uses, Side Effects, Composition & Dosages

This medicine is famous in the pharmaceutical circle as an anti-depression tablet, though its use is not limited to this. It is also used for the control, treatment and prevention of anxiety disorders and neuropathic pain. This medicine form is often resorted when the other medicines fail to show any positive response in the patients of depression. It is manufactured in India by Abbott India Ltd.


Composition and Nature of Prothiaden 25 MG Tablet:

Composition and nature of Prothiaden 25 MG Tablet is quite humble. It only contains one predominant ingredient (salt): Dosulepin (25 MG).


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Uses of Prothiaden 25 MG Tablet:

The uses of Prothiaden Tablet are numerous and not restricted to just one or two. It is widely used not for only the treatment, but also for the prevention and control of the below mentioned bodily conditions:

  • Depression
  • Anxiety Relief
  • Anxiety Disorder
  • Neuropathic Pain
  • Mood Fluctuations
  • Despair feeling


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Side-Effects of Prothiaden 25 MG Tablet:

This is a strong medicine. It has some side effects, which can be countered if taken special care and precaution. The major side effects of the Prothiaden Tablet are:

  • Blurred Vision
  • Hypotension
  • Weight gain
  • Constipation
  • Fluctuation of BP
  • Fluctuating Heartbeats
  • Excessive Sleepiness
  • Urination Difficulties
  • Drowsiness
  • Changes in the levels of libido
  • Dry mouth
  • Excessive Sweating
  • Numbness in the arms and feet
  • Intestinal obstruction
  • Mental Confusion
  • Slurred Speech


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Dosage of Prothiaden 25 MG Tablet:

There is no fixed dosage of Prothiaden Tablet. Different patients are recommended the intake of the medicine very differently. As this is an anti-depressant, you will not be able to see its effect immediately. It may take around 20-50 days to observe all the positive effects of this medicine on the body.


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How Prothiaden 25 MG Tablet works?

The ingredient of the Prothiaden Tablet is known to fluctuate or mainly increase the activity of chemical messengers in the brain. This helps to control and regulate the depression moods of the patient.


Warnings and Precautions Related to Prothiaden 25 MG Tablet:

Although the drug is found to be very effective, it has the power to produce some harmful side effects also after interacting with certain diseases, foods, and drugs. There are a few precautions for Prothiaden Tablet usage. One must not use Prothiaden Tablet, if one is suffering from any of the following bodily conditions:

  • Bipolar Disorder (Manic Phase)
  • Heart Attack/Disorders
  • Allergy
  • Liver Disease
  • MAQI (Monoamine oxidase inhibitors)
  • Epilepsy
  • Prostate Problems
  • Difficulty is urination

Prothiaden 25 MG Tablet must be avoided:

  • If you are already taking monoamine oxidase inhibitor tab.
  • Even after stopping the use of monoamine oxidase inhibitor, do not use it for at least 14 days.
  • Inform the doctor that you are using Prothiaden 25 MG Tablet if you are about to use any anesthetic medicine.


Substitutes for Prothiaden 25 MG Tablet:

There are many substitutes of Prothiaden Tablet that have the exact same composition as that of Prothiaden Tablet. The major known and famous substitutes of Prothiaden Tablet are:

  • Doth (Orchid Chemicals and Pharmaceuticals)
  • Do-Re-Me (Intas Pharmaceuticals)
  • Dothip (Micro Labs)
  • Exodep (Sun Pharma Lab)


Prothiaden 25 MG Tablet Interactions:

Many a drugs have a tendency to interact with certain medicines, food or diseases. This interaction produces some harmful side effects. To save yourself from such side effects, this is highly recommended that you must learn all the interactions of the medicine beforehand. Some known interactions of the Prothiaden Tablet are:

Interactions With Diseases:

  • Heart Diseases
  • Glaucoma
  • Bipolar Disorder

Interactions With Medicines:

  • Flavoxale
  • Ephedrine
  • Hydrochlorothiazide
  • Diazepam
  • Phenobarbital
  • Guanethidine
  • Chlorpromazine
  • Ephedrine
  • Selegiline
  • Cisapride

Interactions With Alcohol:

Prothiaden Tablet is known to interact with alcohol. With alcohol, the medicine can produce some severe side effects like excessive drowsiness, impaired vision and movement, less ability to concentration etc.




1) When can one expect to see the effects of Prothiaden Tablet on his/her body?

Ans: We can say that the effect of this medicine on the body is cumulative. We can observe some positive effects of Prothiaden Tablet in 3-4 weeks after one starts its intake. The medicine is somewhat sleep inducing, and this effect is visible in an hour.


2) How long is the effect of Prothiaden Tablet remains on the body?

Ans: The effect of Prothiaden Tablet remains active on the body for about 6 weeks. However, the reaction to the Prothiaden Tablet varies for different patients.


3) Is it safe to use Prothiaden Tablet with alcohol?

Ans: No, it is not recommended to take Prothiaden Tablet with alcohol. It is because, with alcohol it produces some major side effects like confusion, drowsiness, blurred vision etc.


4) Is it safe to drive or work on a heavy machinery immediately after taking Prothiaden Tablet?

Ans: No, it is not recommended at all. Actually, Prothiaden Tablet have some sleep inducing effect. So any task which requires high mental alertness must be avoided at all costs. You even need to contact a doctor if you feel excessive drowsiness.


5) Is it safe to use Prothiaden Tablet for the pregnant/breastfeeding mothers?

Ans: No, the consumption of Prothiaden Tablet is not recommended for the pregnant/breastfeeding mothers unless utterly necessary. Never take such tablets on your own. Consult your doctor first before taking any medicine.


6) Is the nature of Prothiaden Tablet addictive?

Ans: No the nature of the Prothiaden Tablet has not been found to be addictive at all. Neither the users have reported any addictive nature, not any government organization.


7) Can the consumption of the Prothiaden Tablet be stopped abruptly after one sees improvement in his/her condition?

Ans: No, you must not stop the intake of any medicine abruptly, as some medicines have some rebound effects if stopped abruptly. Doctor’s discretion and words for the dosage should be considered final.


8) Which is the correct time to take Prothiaden Tablet- with food, after the food or before food:

Ans: The correct time to take Prothiaden Tablet is after the food. However, Doctor’s discretion and prescription must be considered final in this case.


9) Which are the major diseases for the treatment of which Prothiaden Tablet is generally used?

Ans: Generally, it is used for the treatment of depression and anxiety disorder


10) For how many times a day Prothiaden Tablet is generally prescribed to be taken by the doctors?

Ans: Though, the prescription varies for different patients, however commonly the doctors prescribes it to be taken once a day or once a week.


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Last updated on : 27-12-2018

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