Safi: Uses, Benefits, Side Effects, Dosage & Price

Safi is commonly used for the treatment of Acne, Skin disorders, Skin diseases, Eczema, Reduced appetite, Dermatologic diseases, Colic constipation, Obesity, Diabetes, and Azoospermia. It is known to control and prevent the diseases to a great extent, if not cure them completely.

The most commonly reported use of syrup is to cure Acne. It is available in syrup form. It is found to be most effective for acne and other skin related conditions. The formulation helps remove impurities from blood and enhance blood circulation.


Uses and Benefits of Safi:

Safi has several uses. They are used for the treatment, prevention and cure of the following diseases and conditions:

  • Acne
  • Skin disorders
  • Skin disease
  • Eczema
  • Reduced appetite
  • Dermatologic diseases
  • Colic constipation
  • Obesity
  • Scorpion sting
    Skin Care
  • Snake bite
  • Dropsy
  • Myalgia
  • Arthralgia
  • Bronchitis
  • Inflammations

Read More: Dabur chyawanprash Uses | Levosulpiride uses  | Sinarest Uses

Safi Price in India:

Medicine Variants                                                                       Price

Hamdard Safi Blood Purifier Syrup (200 ml)                          INR 95

Hamdard Safi Blood Purifier Syrup (500 ml)                          INR 180

Read More: Nimesulide Price | Nicotex Price

Side Effects of Safi:

The use of safi is not without side-effects . Some of the side-effects may be serious, though it is not common and may go away once the course of the medicine is complete.

  • Skin Irritation
  • Muscle fatigue
  • Diarrhoea
  • Burning of skin
  • Vomit
  • Irritation
  • Emesis
  • Drowsiness

As per studies conducted, 30 out of 117 users have reported side-effects post using Hamdard.  The side-effects are of short-term nature most of the times.  Skin irritation is the most commonly reported side effect. It is advisable to consult a doctor in the event you suffer from any discomfort or prolonged side-effects post using the medicine.

Read More: Combiflam Side Effects | Ecosprin Side Effects | Septilin Side Effects

Composition and Nature of Safi:

It is contains the following active components:

  • Senna - 160.45 MG
  • Ipomea Turpethum - 25.45 MG
  • Rosae - 24.77 MG
  • Dalbergia Sissoo - 13.40 MG
  • Santalum Album - 11.36 MG
  • Giloya - 14.09 MG
  • Terminalia Chebula - 22.04 MG
  • Curcuma Zedoaria - 11.36 MG
  • Swertia Chirata - 17.38 MG
  • Cassia Occidentalis - 13.40 MG
  • Gorakmundi - 15.45 MG
  • Gentiana Kurroo - 16.13 MG
  • Vastu Shastra - 22.72 MG
  • Colocasia Esculenta - 15.45 MG
  • Neem - 19.43 MG
  • Tulsi - 13.40 MG
  • Zedoary Root - 11.36 MG
  • Berberis Aristata - 9.43 MG
  • Smilax Ovalifolia - 11.36 MG
  • Prosopis Juliflora - 42.84 MG
  • Evolvulus Alsinoides - 14.09 MG
  • Sharpunkha - 18.06 MG
  • Ushba Maghrabi - 5.68 MG
  • Bacopa Monnieri - 9.09 MG
  • Cassia Absus - 9.09 MG
  • Chlorophytum Borivilianum
  • Shora Desi - 227.27 MG
  • Milleh Firangi - 1.250 GM
  • Dalbergia Sissoo
  • Vastu Shastra
  • Smilax Ovalifolia
  • Prosopis Juliflora
  • Evolvulus Alsinoides
  • Ushba Maghrabi
  • Cassia Absus
  • Shora Desi
  • Milleh Firangi

Common Dosage of hamdard Safi:

The dosage of the safi must be as per doctor’s or pharmacist’s advice.  You can also refer to product package for recommended dosage.

  • The recommended dose of the medicine is:
  • Adults: 10 ml
  • Children: ¼ or ½ of the normal dose i.e. 5 ml
  • It is should be measured from a standard weighing cup.
  • It is should be taken with warm water, and number of dose should not exceed more than twice a day.

Read More: Azithral 500 Dosage | Meftal Spas Dosage

How to take Safi syrup?

  • It can be taken at any time of the day; however, it is suggested to consume it at a fixed interval of time on regular basis.
  • Also, It should be taken in early morning as it also acts as a laxative.
  • Taking the medicine early in the morning helps an individual overcome the stool issues.
  • If not taken in morning hour, then the medicine should be taken half an hour before lunch and dinner.
  • The syrup should be consumed along with warm water.

Safi Suspension:

It is available in syrup form in different specifications. Mostly it includes 200 ml and 500 ml.

How does hamdard Safi Works?

Safi works with the help of histamine, acetylcholine, cholecystokinin, and prostaglandins. It has healing properties and can fight against many diseases due to the presence of alkaloids. Safi contains anti-inflammatory properties and doesn’t allow effects on gastric mucosa.

The properties of the Safi perform functions such as:

  • Reducing duration of fever
  • Reducing duration of infection
  • Antiseptic activity
  • Inhibiting the growth of bacteria, fungi and virus
  • Strong antimicrobial action against both gram positive as well as gram negative bacteria
  • Decreasing pain and swelling
  • Decreasing irritation and anxiety
  • Increasing desire to walk and reducing swelling of joints
  • Helping in anti-cancer action
  • Helping in the treatment of various diseases and ailments
  • Improving the growth of hair
  • Providing strength to the brain and memory, and reducing depression
  • Preventing damage to the liver by modifying body’s immune response
  • Raising libido and sexual vigour
  • Reducing sodium channel activity and increasing pain relief
  • Blocking alpha-1 adrenergic receptor and controlling blood pressure and blood flow to the heart

Medicine not to be taken with Safi:

There are some medicines when taken along with Safi, interferes with the working of the drug. These medicines either alter the effects of Hamdard and worsen the condition; or nullify the effect of either of the medicine.

Here is a list of medicine that should be avoided while consuming the medicine:

  • Warfarin
  • Insulin
  • Lithium
  • Aspirin
  • Heparin
  • Glipizide
  • Dalteparine
  • Azathioprine
  • Glyburide
  • Prednisone
  • Clopidogrel
  • Cyclosporine
  • Enoxaparin
  • Basiliximab
  • Daclizumab
  • Chlorpropamide
  • Glimepiride
  • Rosiglitazone
  • Mycophenolate
  • Sirolimus
  • Pentobarbital
  • Cytochrome P450 enzymes
  • Tacrolimus
  • Tolbutamide
  • Ticlopidine

Precautions and Warnings: When To avoid Safi?

Just as some properties of Safi can make you vulnerable to side-effects.  Some side-effects may cause more damage under certain conditions. It is advisable to avoid using the medicine under following conditions:

  • Autoimmune disorder
  • Breastfeeding
  • Diabetes
  • Pregnancy
  • Planning to get pregnant

Read More: Ecosprin 75 Precautions | Nicip plus Precautions

Substitutes of Safi:

Some substitutes for the drug are:

  • Pravek Safrakt
  • Pravek Safrakt Pack of 2
  • Vasu Uva Acnovin
  • Jiva Neem
  • IMC Aloe Blood Purifier
  • Zandu Lalima Blood and Skin Purifier

Hamdard Safi Interactions:

The effects of a Safi might change if you use it with other drugs or over-the-counter medicines. This may either increase the risk of side-effects or the drug might not work properly.

The medicine may interact with the following drugs:

  • Aspirin
  • Azathioprine
  • Basiliximab
  • Chlorpropamide
  • Clopidogrel
  • Cyclosporine
  • Cytochrome P450 enzymes
  • Daclizumab
  • Dalteparin
  • Enoxaparin


What is Hamdard Safi?

Safi Syrup is Ayurvedic manufactured by Hamdard. It is prescribed as a blood purifier and its main ingredients are naturally available herbs including Tulsi, Neem and Chirata. These ingredients help in keeping the skin clean, smooth and toxin free. It is prescribed for acne and skin disorders usually.

1) Is Safi safe to consume or apply during pregnancy?

Ans: It may cause side-effects or make the side-effects more severe during pregnancy. Hence, it is advisable to avoid consumption of this syrup during pregnancy.  However, do consult your physician for case specific recommendations.

2) Is Safi Syrup safe to consume or apply during breastfeeding?

Ans: The Syrup may cause side-effects or make the side-effects more severe during breastfeeding. However, it is advisable that you discuss the risks and benefits with your doctor.

3) Can I use Safi for acne and skin related disorders?

Ans: It is most commonly used for treatment of acne and skin orders. Please consult with your doctor first before you use the drug to treat acne or skin disorders.

4) How long do I need to use Safi before I see improvement of my conditions?

Ans: Based on surveys done, 1 month and 1 week is the most common duration before you can see improvements in your condition. However, the results vary from person to person. It is advisable that you consult with your physician to understand how long you need to use Safi.

5) At what frequency do I need to use Safi?

Ans: The most common frequency of using Safi is once a day or twice a day. However, it is recommended that you consult your doctor to understand how often you need to take this.

6) Should I consume Safi on empty stomach, before food or after food?

Ans: It is mostly consumed after meals. However, it is best to take the doctor’s advice on how you should consume this.

7) Is Safi Syrup addictive in nature?

Ans: Medicines that have potential of addiction or can lead to habit formation are categorized as controlled substances. You will have to check the product package to understand if this medicine falls under any such special categorizations. Also, it is always advisable to avoid making the body too dependent on medicines without the advice of a doctor.

8) Is it safe to drive or operate heavy machinery after consuming Safi?

Ans: A person must not drive or operate any heavy machinery after consuming safi which makes him drowsy, dizzy or causes any kind of immediate side-effect in his body. If this drug causes any such side-effect on you, please do not drive or operate heavy machinery post consuming it.

9) Can it be stopped immediately or do I have to slowly wean off consumption?

Ans: Please consult with your doctor on this as some medicines do produce a rebound effect and therefore have to be weaned off slowly.

10) What are the advantages of Safi?

Ans: Safi contains Chirata, Neem and Tulsi as its main ingredients. These ingredients help fights acne and mitigate pimples by making the skin toxin free. It is also found to be beneficial for thyroid and liver and removes the toxins that cause skin issues.

11) How does blood purifier works while having safi?

Ans: The blood purifier works by cleansing the blood and entire lymph system; along with maintaining balance. Several herbs present in the purifier helps to stimulate T cells function and enhance the count of white blood cells, clean toxins from the blood and reduce inflammation.

12) When should I drink Safi?

Ans: It is an Ayurvedic medicine which helps remove toxins from the blood. Hence, you can drink this syrup for digestive concerns such as bloating, infection, and constipation. It is also helps in weight loss, skin problems and promotes metabolism.

13) Does Safi clear pimples?

Ans: Yes, the syrup clears pimples.Safi is a natural blood purifier for skin and flushes out all toxins from the body; thereby it helps cure pimples.

14) How to use Safi?

Ans: It should be taken twice a day along with warm water. It is advised to take the drug half an hour before lunch and dinner.

15) How often do I need to take safi?

Ans: The frequency of Safi dosage varies according to the condition of the person. For an individual suffering from constipation the medicine should be consumed twice a day with warm water. In case of other conditions, it should be taken with a cup of water, milk or fruit juice at least for 20 days.

16) Can we take Safi during the period?

Ans: Yes, This can be taken during the period. However, it is advised to drink plenty of water in this duration or else adverse reaction may start in the body.

17) Does Safi delay periods?

Ans: Safi is known to clean the blood and regularize the period. However, if not used properly it might result in electrolyte imbalance leading to delay in periods.

18) What are the ingredients of Safi Syrup?

Ans: Safi is a Unani medicine which contains natural herbs as its main ingredients. Some of the herbs used in the medicine include chiraita, shahtra, neem, zarambad, giloy, shora desi, senna, sandal surkh, mundi and tulsi. These ingredients exhibit anti-inflammatory, antimicrobial and antiviral property.

19) Is Hamdard Safi syrup recommended for glowing skin?

Ans: Safi syrup helps remove the toxin from the blood thereby clears pimples and acne. If used regularly it can result in glowing skin.

20) Is Hamdard Safi syrup safe for consumption by a child?

Ans: It is safe for children above 12 years. However, it is advised to ask apediatrician before providing the medicine to children.

21) Is Hamdard Safi syrup recommended for constipation?

Ans: Yes, Safi syrup is found to be effective for constipation.

Read More: Becosules | Becadexamin | Azee 500 | Serratiopeptidase

Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

User Comments (4)



Fri Apr 05 2019

Has Saafi got any aresenic or lead ? I have been taking it for over 15 years


Amamata salihu

Fri Jun 21 2019

Any improvement? I want to go for the drug but am scared



Sun Apr 21 2019

can i take safi in the condition of RoA



Thu May 02 2019

can i take safi with apple cider vineaga ? can i take safi with Garcinia Cambodia tablets



Fri Jul 12 2019

is it ok to take safi while taking Hypertension medicine like Larsatas and Atenalol?


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