Signoflam Tablet: Uses, Side Effects, Dosage & Price

With the kind of lifestyle people lead nowadays it is often that they complain of various pains across the body. This may be due to various factors like lack of sleep, food, water, or rest, but the number of people suffering from even minute pains is very large. As a result, there are a lot of medicines that have been made available to help relieve people of the same, and one such medicine is Signoflam .

Signoflam Tablet

Uses and Benefits of Signoflam:

Signoflam is used to provide relief from pain occurring due to conditions like headache, musculoskeletal pain, painful menses, and mild migraine. Signoflam Tablet is also given to people with painful rheumatic conditions like osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis. Apart from this, some of the other times is can be used are:

  • Pain during Menstruation
  • Bone and Joint Pains
  • Sore throat
  • Ear infections
  • Arthralgia
  • Toothache
  • Cold
  • Muscle Pain
  • Osteoarthritis
  • Pain caused by nonarticular rheumatism
  • Headache
  • Fever
  • Post Surgery Pain
  • Rheumatoid Arthritis
  • Spondylitis
  • Periarthritis of scapulohumeral
  • Swelling
  • Bloating
  • Ear pain
  • Lumbago
  • Flu
  • Migraine
  • Blood clots
  • Ischiadynia

Read More: Monticope Uses | Bgr 34 Uses

Side Effects of Signoflam:

While most dangerous side effects of Signoflam Tablets are of rare occurrence, they can still be serious in nature. Here is a list of side effects that may arise due to consumption, so that patients can stay alert against them:

If a patient gets any allergic reactions due to Signoflam, they must contact the doctor immediately.

Read More: Aciloc 150 mg Side Effects | Domstal 10 mg Side Effect

Common Dosage of Signoflam:

Signoflam Tablet should be taken in the dose and at the time that is suggested by the physician. Signoflam should be swallowed as whole, and the patient must not chew, crush, or break it for any reason. Completing the dose is crucial to ensure  condition could continue worsening. It should be remembered that  if a patient is under any other kind of medication, they should inform the physician of the same. Sometimes, suffering from some other health issues can lead to susceptibility to side effects, so informing the doctor of any such conditions is important. For best results, Singnoflam should be consumed with food or immediately after eating.

If a dose of Signoflam is missed, then Signoflam Tablet should be taken as soon as one remembers, but if it is too close to the next dosage time, then it should be skipped. If an overdose occurs, then call the doctor immediately.

Read More: Drotin Dosage | Grilinctus Dosage

Composition and Nature of Signoflam:

Signoflam Tablet is made up of Aceclofenac (100 mg), Paracetamol (500 mg) and Serratiopeptidase (15 mg). It is prescribed when any other single painkiller fails to provide much relief from pain. Signoflam is manufactured by Lupin Ltd and comes in the form of a tablet. It is a non-steroidal anti-inflammatory drug (NSAID).

Read More: Domstal 10 mg Composition | Aciloc 150 mg Composition

Precautions and Warnings- When to Avoid Signoflam Tablet:

Alcohol must be avoided during Signoflam dosage period, as interactions could lead to liver damage. The drug’s interaction in women who are pregnant or lactating is unknown, so it is best to consult the physician. There is also limited data regarding consumption by kidney and liver patients, so they should also make a trip to the doctor’s office before deciding to take Signoflam.

Consuming Signoflam Tablet can make patients feel dizzy and affect their vision, and if that is the case, they should avoid driving. As an extension, they should also not use heavy machinery when under dosage and feeling these symptoms.

Read More: Precautions and Warnings of Montair Fx | Precautions and Warnings of Mobizox

Substitutes of Signoflam Tablet:

Some of the substitutes for Signoflam Tablets are:

  • Ibugesic Asp 100 mg/325 mg/15 mg tablet (manufactured by Cipla Ltd)
  • Rexonac SP (Rexion Healthcare Pvt Ltd)
  • Willgo SP tablet (Panacea Biotec Ltd)
  • Acutec SP tablet (Glebit Laboratories)
  • Voltanec SP 100 mg/325 mg/15 mg tablet (Cipla Ltd)
  • Movace SP tablet (Alkem Laboratories Ltd)
  • Vivian A Plus (Lincoln Pharmaceuticals Ltd)
  • Ultiflam SP tablet (Skymax Life Science Pvt Ltd)
  • Seraheal tablet (Ipca Laboratories Ltd)
  • Acevah PS 100 mg/325 mg/15 mg tablet (Abbott India Ltd)
  • Tremendus-SP tablet (Grandcure Healthcare Pvt Ltd)
  • Lysonac Asp (El-Dorado Bio-Tech Pvt Ltd)
  • Bignac SP tablet (Ronyd Healthcare Pvt Ltd)
  • Zubol SP (Diverse Health Services)

Read More: M2 Tone Substitutes | Lobate GM Substitute

Signoflam Tablet Interactions with Other Drugs:

Drug interactions could change the workings of any prior medication and can also increase the risk of any serious side effects. It is best not to start, stop, or change dosage of any medication unless patients have got approval from their doctor. they should not consume Signoflam if they are consuming the following drugs:

  • Aspirin
  • Lithium
  • Corticosteroids
  • Digoxin
  • Clopidogrel
  • Antihypertensives
  • Dalteparin
  • Aliskiren

Patients should also avoid Signoflam Tablet if they have any of the following conditions:

  • Problem with stomach or duodenal bleeding (like an ulcer)
  • Heart conditions
  • High blood pressure /blood clotting problems

Read More: Interactions with limcee | Interactions with levolin

Signoflam Tablet Price in India

  • Signoflam P -100mg/500mg Strip of 10 Tablet – Rs. 37.5
  • D-Signoflam: Tube of 30gm Gel – Rs. 119.85
  • Signoflam Tablet: Strip of 10 Tablets - Rs. 97.85

Read More: Acnestar Gel Price | Aldactone Price

How Signoflam Tablet works?

Signoflam three components (Aceclofenac, Paracetamol, Serratiopeptidase) help in relieving pain. Aceclofenac and Paracetamol (Acetaminophen) block the secretion of specific chemical messengers in the brain which can cause pain and fever. Serratiopeptidase destroys bad proteins around the inflammation site, which helps promote healing. Signoflam also blocks effects of cyclooxygenase (COX) enzymes, which create chemical prostaglandins at the area of damage or injury, and this can lead to pain, inflammation and swelling. Blocking of COX eases pain and reduces inflammation.

How to use Signoflam Tablet?

Take the dose of Signoflam as advised by the doctor. Signoflam should be consumed orally. Don’t swallow, chew or break the tablet. Signoflam can be taken with meals. Patients should make sure that Signoflam is not taken on an empty stomach or else they might face severe health issues. For the best results of Signoflam, the patients should make sure that Signoflam is taken on regular intervals or as prescribed by the doctor so that the level of medicine in the body is maintained. Don’t stop Signoflam Tablet in between or else it might lead to severe side effects and symptoms and patients may need to start the dose again.

When is Signoflam Tablet prescribed?

Signoflam is prescribed for providing relief from pain in some of the conditions like migraine, headache and musculoskeletal pain.

  • Rheumatoid arthritis: Signoflam can be used to treat symptoms like body pain; stiffness and swelling that are associated with Rheumatoid arthritis
  • Osteoarthritis: Signoflam can be used to treat symptoms like painful and tender joint pain that are associated with Osteoarthritis.
  • Ankylosing spondylitis: Signoflam can be used to treat symptoms like pain and stiffness that are associated with Ankylosing Spondylitis.

Signoflam Tablet is prescribed to the patient in the conditions mentioned below:

  • Pain in the ear
  • Pain due to rheumatoid arthritis
  • Ankylosing spondylitis
  • Osteoarthritis
  • Headache
  • Gynaecological pain
  • Joint pain
  • Tooth pain

Is Banned Signoflam Tablet in India?

Signoflam is legal in India and the sale of this medicine is not banned. Signoflam Tablet is available on the prescription of the doctor and patients should not self-medicate under any circumstances.

Medicines not to be taken with Signoflam Tablet:

Patients’ currently consuming different medications or are under any kind of therapy should disclose the information to the doctor before starting the course of Signoflam. There may be some medicines that might interact with Signoflam Tablet and show side effects. The doctor should also be informed about the vitamin, herbal supplement and drugs been consumed by the patients, beforehand. This will help the doctor in giving the patients the right substitutes of the Signoflam, thus preventing drug interaction.

Here is the list of drugs that interact with Signoflam tablet.

  • Ibuprofen
  • Juxtapid mipomersen
  • Heparin
  • Enoxaparin
  • Diclofenac
  • Aspirin
  • Dalteparin
  • Naproxen
  • Prilocaine
  • Teriflunomide
  • Leflunomide
  • Ketoconazole
  • Warfarin

How to Store Signoflam Tablet?

  • Make sure that you don’t keep Signoflam in the direct sunlight or heat.
  • Keep Signoflam tablets away from children and pet.


1) Can Signoflam Tablet be stopped immediately, or do I have to gradually end consumption?

Ans: Some medicines need to be slowly weaned off as they could have rebound effects. It is best to consult your doctor for body-specific recommendations since it depends on your specific condition.

2) Is Signoflam Tablet addictive?

Ans: Signoflam is not addictive, generally. Addictive medicines normally come under schedule H or X in India. Read the package information carefully before using to gain information regarding the same.

3) Will Signoflam Tablet usage help with GERD?

Ans: No. Signoflam Tablet isn’t going to help with anything related to GERD, but you can perhaps use an antacid after consulting a gastroenterologist .

4) Can I use substitutes if Signoflam Tablet is unavailable?

Ans: Yes, one can use substitutes when the Signoflam is unavailable, but this must be done only after consulting the physician.

5) What are the substitutes that can be used for Signoflam?

Ans: One should only take substitutes if Signoflam is not available. Some substitutes that can be used are Ibugesic Asp, Willgo SP tablet, Ultiflam SP tablet, Bignac SP tablet, and more.

6) How much time does Signoflam Tablet takes to show its effect?

Ans: You can see the effect of Signoflam Tablet in one to three hours after taking it orally.

7) Can I take Signoflam Tablet with alcohol?

Ans: No, you should not take Signoflam with alcohol as it can have severe side effects. It is advisable to discuss with the doctor if you drink alcohol so that the doctor can give you a better medical guidance and provide with alternative medicines in some cases.

8) Can I have Signoflam Tablet if I am pregnant?

Ans: No, you should not take Signoflam Tablet if you are pregnant. If it is urgent then we advise you to consult your doctor.

9) What precautions should I take before taking Signoflam Tablet?

Ans: It is advisable to inform your doctor about any kind of medication or therapy that you are going through. You should also take the dosage after reading the instruction and also according to the guidance given by the doctor.

  • Signoflam should not be consumed in the conditions mentioned below:
  • Severe cardiac impairment
  • Breastfeeding
  • History of gastric ulceration
  • Pregnancy
  • Gastrointestinal disorders
  • Avoid driving or operating heavy machinery after taking Signoflam Tablet
  • Patients recovering after a surgery
  • Bleeding disorders
  • Avoid using it if allergic to Paracetamol

10) Can I use Signoflam used for joint and muscles pain?

Ans: Yes, you can use Signoflam for bones and joint pain as it is used by the patients for such conditions. However, make sure that you consult your doctor and take Singnoflam only after proper prescription. There are chances that you might have serious health issues if you have taken Signoflam without prescription of the doctor.

11) How long do I need to continue the dose of Signoflam tablet in case I see improvement in the body?

Ans: You should not stop the dose even if you see the improvement because there are chances that you might have symptoms in the next few days. So, it is better to complete the dosage of Singnoflam Tablet. In case if you want to stop on an immediate basis then consult your doctor and discuss the same.

12) When should I avoid the consumption of Signoflam?

Ans: Signoflam should not be consumed in the following cases:

  • If you are allergic to any of the component in Signoflam.
  • If you are allergic to Non-steroidal Anti-inflammatory drug (NSAID) or Aspirin like Diclofenac.
  • Don’t take if you have taken any NSAID in past and have faced symptoms like an asthma attack, itchy red bumps, irritation on nose or bleeding in the stomach.
  • Kidney or liver disease
  • Stomach or intestine ulcer
  • Breathing problem
  • Bleeding or blood clotting disorder

13) What are the tips for taking Signoflam Tablet?

You should drink a decent amount of water to reduce indigestion and stomach irritation. You should take the Signoflam tablet with milk or food to avoid stomach upset. Complete the dosage and if in case you still have the symptoms then don’t start the course of Signoflam again or else it may increase the chances of stomach bleeding.

14) Is Signoflam a painkiller?

Ans : Yes, Signoflam is an analgesic and antipyretic drug which is used to treat mild to moderate pain. It can be used in treating various conditions such as joint pain, fever, headache, painful rheumatic arthritis, ear pain, toothache, bloating sore throat etc.

15) What is Signoflam Tablet used for?

Ans : Signoflam belongs to a class of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). It can be used for treating, preventing and controlling symptoms and conditions such as ear pain, headache, toothache, painful rheumatic arthritis, fever, joint pain, fever, sore throat, bloating etc.

16)  How to take Signoflam Tablet?

Ans : The dose of Signoflam is decided by the doctor after examining the patients’ medical history and current medication, if any. The tablet has to be swallowed whole, and should not be broken, crushed or chewed. It is advised to continue the prescribed course of Signoflam and not to stop it once the patient starts feeling better. It is advisable that Signoflam tablet should be consumed after meals.

17) Is Signoflam safe to use during breastfeeding?

Ans . Signoflam is not recommended for use during breastfeeding. It is suggested to consult the doctor before taking this medicine.

18) What are the reported allergic reactions after administering Signoflam tablet?

Ans: Signoflam tablet should not be taken if the patient suffered from listed below allergic reaction:

  • Allergic to the ingredients of the medicine
  • Bleeding disorders
  • Acute rhinitis
  • Active peptic ulcer
  • Asthma
  • Blood coagulation disorders

19) Can I use Signoflam tablet in the treatment of toothache?

Ans : Yes, Signoflam tablet can be used in the treatment of toothache. It is a painkiller which belongs to a class of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) used to treat mild to moderate pain.

20) Can I use Signoflam tablet for the treatment of piles?

Ans : No, Signoflam tablet can’t be used for the treatment of piles. It is advisable not to self-medicate, consult a doctor.

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Last updated on : 26-09-2019

Disclaimer : Docprime doesn’t endorse or take any guarantee of the accuracy or completeness of information provided under this article and these are the views strictly of the writer. Docprime shall not be held responsible for any aspect of healthcare services administered with the information provided on this article.

User Comments (3)



Wed Feb 06 2019

Does Signoflam Tablet reduces headache?



Wed Feb 06 2019

What are age limits for consumption of Signoflam Tablet?



Tue May 07 2019

Can I use Signoflam to treat Bicep Tendonitis ?


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