Typhoid is caused by bacteria called Salmonella Typhi. Typhi Dot IgM test is done to check IgG and IgM antibodies against Salmonella typhi bacteria.
People with high fever for more than 3 days should go for this test. The test shows a positive response in around 2 to 3 days of the infection. It primarily identifies IgG and IgM antibodies.
The level of IgM indicates infection in the body and on the other hand, IgG identifies remote infection. This test is performed by general physicians or doctor to identify typhoid disease.
Procedure involved in Typhidot IgG/IgM test
The doctor or a specialist might ask the patient about the symptoms, medical history and any kind of antimicrobial treatment
The surface or area, from where the blood is to be withdrawn, is cleaned with the help of an antiseptic
The blood test is conducted by the specialist with the help of Venipuncture in which blood is taken from the veins
The specialist then applies a bit of pressure on the area for an easy flow of blood
Cotton or gauze is used to stop bleeding
Blood is then transferred to the laboratory within two hours of collection.
Why get tested?
Typhidot IgG/IgM test is performed to check typhoid bacteria in the body of the patient. It is an indirect solid phase immunochromatographic that is used to detect and differentiate IgG and IgM antibodies against Salmonella typhi in the human blood, plasma or serum. The result of the test gives positive or a negative reaction to antibodies.
The effectiveness of the test has shown specificity and sensitivity of 86% and 95% respectively. It has a decent diagnostic value among children with typhoid fever. Early productions of antibodies are mainly IgM in nature. If in case, IgM antibodies are detected instead of IgG or both IgM and IgG in the test then it may be a sign of recent infection.
This test includes
The test is performed by the general physician or doctor when a patient reports fever for 4 days or for a week. Patient has to give blood sample for the test
Before the test, the general physician advise the patient to stop taking medicines as it can affect the test
Some of the common medicines that people should not take are antacids, laxatives, and water pills
It is imperative to inform the doctor about any other symptoms or health issues before the test
People who have recently taken international trip should also inform the doctor
The patient should inform the doctor about the time period of fever and symptoms