Wysolone is a steroid medicine manufactured by Pfizer Ltd. which is prescribed for the treatment of several disorders, including allergic reactions, eye disorders, Asthma, skin disorders, rheumatic disorder, and Nephrotic syndrome.
Nature of Wysolone Tablet : Steroid medicine
Composition of Wysolone Tablet: Prednisolone
Uses and Benefits of Wysolone Tablet: Blood infections, eyes inflammation, respiratory diseases, rheumatoid arthritis, skin disorders
Precautions: Consume with food, patients with allergy to steroids must avoid, patients with conditions like cirrhosis, peptic ulcers, diabetes mellitus, kidney problems, hypertension or heart disorders must avoid
The Wysolone works by inhibiting the action of certain hormones in the body which lead to inflammation and provides symptomatic relief of Lupus, Psoriasis, Asthma, and other such disorders.
Corticosteroids present in the body are responsible for reducing inflammation. The active ingredient present in Wysolone is Prednisolone which gets absorbed in the bloodstream and enhances the level of corticosteroids in the body.
Uses and Benefits of Wysolone:
Wysolone is used in the symptomatic treatment of several disorders and diseases like
Immune system disorders
Idiopathic Thrombocytopenic Purpura
Toxic Epidermal Necrolysis
Chronic Lymphocytic Leukaemia
Irritable Bowel Syndrome
Rheumatic Heart Disease
Juvenile Rheumatoid Arthritis
Patients who have severe allergic reactions leading to swelling of eyes and other reactions are commonly prescribed Wysolone.
Patients with skin disorders or respiratory diseases leading to inflammatory responses can also consume Wysolonemedicine.
Patients with Rheumatoid Arthritis may also be prescribed Wysolone.
Other diseases where Wysolone may be administered include blood disorders, gastrointestinal disorders, or cancer.
As a steroid, Wysolone may cause a number of side-effects. If taken in the correct dosage, the side-effects are usually minimal and go away once the course of the medicine is complete. However, if side-effects do not fade away, or become worse, then the patient should seek medical attention as soon as possible. Most side effects occur with high doses and due to prolonged use. Unless unavoidable, Wysolone should not be stopped abruptly, it should be decreased gradually.
Common side-effects of consuming Wysolone include:
Altered menstrual cycle
Increased risk of infection
Increased hair growth
High blood pressure
Redness of skin
Scars on skin
Delayed wound healing
High level of glucose in the body
Life-threatening side effects of Wysolone:
Anaphylaxis - A very serious allergic reaction
Arachnoiditis - Inflammation of the spinal cord
Meningitis - Inflammation of the spinal cord and brain
Vasculitis - Inflammation of the blood vessels
Bleeding in stomach and intestines
Other side-effects of Wysolone:
While mood swings are common, the patient should be seek immediate medical attention in case the mood swings are frequent and recurring.
The medicine may lead to symptoms of psychotic disorder, in which case the patient requires immediate medical attention.
Wysolone should only be consumed on the advice of a doctor. The doctor will prescribe a dosage on the basis of the patient’s health and present condition. The practitioner may have to study the medical history of the patient to decide whether or not to prescribe Wysolone. The tablets should not be chewed or swallowed entirely. It should be allowed to dissolve briefly in the mouth with water if needed. Here are some of the doses that the doctor may prescribe to different patients:
Wysolone Dosage For adults
The doctor may recommend a tablet of 200mg per day for an entire week, followed by a dose of 80 mg every day for approximately 30 days.
Wysolone Dosage For children -
Initially, a dose of 0.14 mg – 2 mg may be prescribed per day depending upon the severity of the condition.
Wysolone Dosage for children suffering from Nephrotic Syndrome
A dose of 60 mg divided into 3 doses may be given every alternate day for four consecutive weeks.
Wysolone Dosage for children suffering from Asthma
1 – 2 mg of dose may be prescribed in the form of single or divided doses for 3 to 10 days.
Wysolone Dosage for adults suffering from Collagenosis
Initially, the doctor may begin by prescribing a dose of 5-15 mg per day, after which depending upon the patient’s improvement the dose may be increased or decreased.
Wysolone Dosage for adults suffering from Rheumatoid Arthritis
A dose of 10-15 mg per day may be prescribed by the doctor for patients suffering from Rheumatoid Arthritis.
Wysolone Dosage for adults suffering from Lymphoma
A dose of 15 to 60 mg per day may be prescribed till the time improvement in patient’s condition is not witnessed.
Wysolone Dosage for adults suffering from blood-related disorders
An initial dose of 15 – 60 mg per day may be prescribed by the doctor to the patients suffering from blood-related disorders.
First and foremost when a patient is prescribed Wysolone, he/she must read the medicine guide offered by the medicine company. If there are any doubts pertaining to the medication or dosage, it must be clarified after discussing with the doctor.
The Wysolone Tablet must be taken with food and not on empty stomach to avoid irritation in intestines. Also, the tablet has to be swallowed with or without water. Do not chew, split or break the tablet before eating. Depending upon the severity of the condition, the medicine is prescribed for a period of several day ranges. Initially, the doctor may start by prescribing a lower dose to comprehend its impact on the body and lower the side effects.
How Wysolone Tablet works?
Wysolone belongs to the group of steroidal drugs called glucocorticosteroids, Prednisolone is its active ingredient which can inhibit leukocyte infiltration at the site where inflammation has occurred. The medicine interferes with the mediators of the inflammatory response and suppresses the humoral immune response. It further possesses phospholipase A2 inhibitory proteins which control the biosynthesis of inflammation mediators like leukotrienes and prostaglandins. The compound restricts the accumulation of polymorphonuclear leukocytes and macrophages to reduce the release of vasoactive kinins (substances formed in the body in response to an injury).
Apart from treating inflammation, Wysolone has positive effects on the metabolism of the body and boosts the immune system as well.
When Wysolone is prescribed?
Wysolone Tablets are prescribed if a person is suffering from allergies, inflammation, autoimmune disease, skin and eye related problems and certain forms of cancer.
Specific conditions in which the Wysolone medicine is prescribed include -
Precautions and Warning - When to Avoid Wysolone?
Before a person starts consuming Wysolone, he/she must tell their doctor about any medical condition or on-going medication. This will help the doctor to evaluate if there will be any side effects or risks pertaining to the consumption of the medicine. Read on to know the precautions that must be taken while/before taking this medicine.
Wysolone should be consumed with food to ease the effects on the stomach.
Patients with fungal infections should avoid Wysolone.
Patients who are allergic to steroids or any of the ingredients of Wysolone should use a different medicine.
After prolonged use of high doses, risks of getting infections may be higher. If the patient develops persistent symptoms like fevers, wounds, coughs, painful urination or symptoms of the flu then the patient should seek medical advice.
Patients with pre-existing health issues such as Cirrhosis, Peptic Ulcers, thyroid problems, Diabetes Mellitus, kidney problems, hypertension or heart disorders, depression, or any muscle disorder, are not recommended to use Wysolone. The patient should inform the doctor at the earliest and stay informed about the side effects. The doctor may suggest an altered dose that is suitable for the patient’s health.
Patients with a history of Psychoses, especially untreated disorders are also not recommended to consume this medicine as it may lead to adverse effects.
The use of this medicine may alter intraocular pressure (pressure of fluids inside the eyes).
Continuous use of Wysolone may raise the blood pressure and alter the sodium and potassium levels in the blood.
Use of this medicine in the first trimester of pregnancy may increase the risk of congenital abnormalities of lips and mouth of the unborn child. Its use may also lead to restricted growth of the foetus in the uterus and decrease birth weight.
The Wysolone may cause the stomach to bleed and the chances may increase in case a person who drinks or smokes regularly.
It is suggested that the people suffering from infectious diseases must be avoided as it may be contagious and worsen the patient’s condition.
Since wound healing becomes slow, care should be taken that no such activity is done that may cause any sort of injury, cut or bruise.
Younger patients may be more prone to the side effects of the Wysolone medicine.
Use of this medicine may increase blood pressure, water or salt retention and the secretion of potassium which may be a bit risky for patients suffering from congestive heart failure, kidney failure and high blood pressure.
Use of Wysolone may have an effect on the endocrine system leading to hormone suppression.
Substitutes of Wysolone:
The most common substitutes for Wysolone are
Omnacortil manufactured by Macleods Pharmaceuticals Pvt Ltd
Omnacortil Forte manufactured by Macleods Pharmaceuticals Pvt Ltd
Predone manufactured by Cipla Ltd
Mornipred manufactured by Zydus Cadila
Pred Forte manufactured by Allergan India Pvt Ltd
Kidpred manufactured by Abbott
Prednisolone Acetate manufactured by Alcon Laboratories
Emsolone manufactured by Medo Pharma
A number of other medicines may be unsafe to use concurrently with Wysolone, including –
Wysolone Interaction with alcohol –
The consumption of Wysolone tablets with alcohol induces sleepiness. The tablet may also cause seizures in some people. In case a person experiences loss of consciousness while on medication, the doctor must be consulted.
Wysolone Interaction with diseases –
Diabetes - In the case of diabetes the corticosteroids may raise the level of sugar in the body, therefore it is imperative to keep an eye on the blood sugar levels while on this medication.
Neurodegenerative Conditions - Patients taking anticholinesterase agents which are used for the treatment of conditions like Dementia, Alzheimer's, and Parkinson’s disease etc. may interact with Wysolone and cause severe weakness in the skeletal muscles.
Wysolone Interaction with Other medicines -
Azole antifungal agents: Use of Itraconazole and similar azole antifungal drugs must be avoided as the concentration of Wysolone in the body will become very high and may lead to a number of dangerous side-effects such as high blood sugar and swelling. In the case of children, the medicine may lead to problems in growth. Doctors may choose to prescribe an alternative (particularly for children) or adjust the dose of the medicine.
Gastrointestinal diseases: Wysolone should be used with caution by patients with gastrointestinal disorders. There is an increased risk of dangerous bleeding when Wysolone is taken for extended durations. Doctors may adjust the dosage.
Non-steroidal anti-inflammatory drugs: Physicians will advise against the consumption of Wysolone with non-steroidal anti-inflammatory drugs. The concurrent use of these may put the patients at high risks of gastrointestinal bleeding. The patient’s physician can best advise whether or not to use an alternative medication.
Ethinyl Estradiol: Consuming this medicine with Ethinyl Estradiol will increase the concentration of Wysolone in the body. The physician may choose to recommend a replacement or make dosage adjustments to Wysolone.
Antihypertensive: Consumption of Wysolone with most antihypertensive will decrease the concentration of antihypertensive, particularly if both are used together for longer than seven days. The patient may be prescribed an alternative, or the doctor may change the dose or the duration of Wysolone.
Fluoroquinolone: With concurrent consumption of Fluoroquinolone with Wysolone, the patient is at a constant risk of pain, or inflammation in their shoulder, ankle, hands, or thumbs. Elderly patients with a known history of kidney or heart disorders are at a greater risk. For better results and faster recovery of the patients, the doctor may change the medicine under close supervision.
Following are the variants of Wysolone-
Wysolone 5 Tablet DT
Wysolone 10 Dispersible Tablet
Wysolone 20 Tablet DT
Wysolone 30mg Tablet
Wysolone 40mg Tablet
Wysolone 5mg Tablet
Wysolone Tablet Suspension:
Prednisolone Acetate Suspension is a synthetic form of a corticosteroid hormone. It is used to treat conditions like severe allergies, Arthritis, immune system disorders, breathing problems etc. The medicine must be taken orally with food or milk as directed by the doctor. Several brands manufacture the liquid prednisolone, therefore read the dosage instructions carefully before consumption.
Wysolone should not be taken with Following Medicines:
Following are the medicines that must not be taken with Wysolone, as they may counter interact with other medicines and alter their effect. These interactions may harm the body and worsen the patient’s conditions. Here is a list of medication that must be avoided –
How to store Wysolone Tablet?
Following are the instructions for the proper storage of the Wysolone medicine:
The Wysolone should be stored at room temperature.
It must be stored away from places from where it can soak moisture like a bathroom or near the sink.
Wysolone is also recommended that the medicine must be kept away from direct sunlight and excessive heat.
Keep the Wysolone away from the reach of children and pets.
Do not open the pack until the medicine has to be consumed.
1) What is Wysolone used to treat?
Ans: The Wysolone is used to treat various inflammatory diseases.
2) What is Wysolone used for?
Ans: The Wysolone is used for the treatment of various diseases like Multiple sclerosis, Immune system disorders, Asthma, Arthritis, Nephrotic Syndrome, Idiopathic Thrombocytopenic Purpura, Chronic Lymphocytic Leukaemia, Dermatitis Herpetiformis, Osteoarthritis, Polymyositis, Psoriasis, Seborrheic Dermatitis, Rheumatic Heart Disease, Juvenile Rheumatoid Arthritis, Eye Discharge, Rheumatic Disorder etc.
3) What are the side effects of Wysolone Tablet?
Ans: Some of the side effects after the consumption of Wysolone include weight gain, abdominal pain, bone degradation, altered menstrual cycle, decreased libido, excessive sweating, fatigue, high blood pressure, redness of the skin, scars on the skin, delayed wound healing, increased risk of infection, increased hair growth etc.
4) Can a pregnant or breastfeeding patient use Wysolone?
Ans: No adverse reactions have been reported in babies who are being breastfed by patients using Wysolone. However, the medicine may cause severe health problems in unborn child and therefore pregnant mothers must take this medicine after consultation with their doctor.
5) What happens if a person takes an overdose of Wysolone?
Ans: An overdose of Wysolone may prove to be harmful to the body. In the case of long-term intoxication, it is imperative to consult a doctor. Vomiting and gastric lavage may help to reduce the toxic effects of the Wysolone if there is no relief immediately consult a doctor.
6) Does Wysolone Tablet cause severe mood swings?
Ans: Yes, continuous consumption of Wysolone leads to behavioral and mood changes including depression, insomnia, euphoria and other personality changes.
7) How to dispose of the expired Wysolone?
Ans: Read the disposal instructions given on the Wysolone pack and follow them.
8) How long a person can safely take Wysolone Tablet?
Ans: There is no such definite answer for this. The Wysolonemust only be taken with a proper description from a doctor. The extent of taking a medication will depend on the patient's condition and the pace of his/her recovery.